{"id":857,"date":"2019-02-21T09:20:16","date_gmt":"2019-02-21T01:20:16","guid":{"rendered":"http:\/\/www.puriactives.com\/en\/?page_id=857"},"modified":"2019-02-21T09:44:58","modified_gmt":"2019-02-21T01:44:58","slug":"platform-technology","status":"publish","type":"page","link":"http:\/\/www.puriactives.com\/en\/?page_id=857","title":{"rendered":"Platform Technology"},"content":{"rendered":"<div id=\"pl-857\"  class=\"panel-layout\" ><div id=\"pg-857-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-857-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-857-0-0-0\" class=\"so-panel widget widget_siteorigin-panels-postloop panel-first-child panel-last-child\" data-index=\"0\" >\n\n\t\t\n\t\t\n<article id=\"post-1250\" class=\"post-1250 post type-post status-publish format-standard hentry category-news\">\n\n\t\n\t<div class=\"entry-main\">\n\n\t\t\n\t\t<header class=\"entry-header\">\n\t\t\t\n\t\t\t<h1 class=\"entry-title\"><a href=\"http:\/\/www.puriactives.com\/en\/?p=1250\" title=\"Permalink to NanoActive BENZYL URSOLATE\" rel=\"bookmark\">NanoActive BENZYL URSOLATE<\/a><\/h1>\n\n\t\t\t\t\t\t\t<div class=\"entry-meta\">\n\t\t\t\t\tPosted on <a href=\"http:\/\/www.puriactives.com\/en\/?p=1250\" title=\"23:20\" rel=\"bookmark\"><time class=\"entry-date\" datetime=\"2026-05-13T23:20:32+08:00\">05\/13\/2026<\/time><\/a><time class=\"updated\" datetime=\"2026-05-13T23:20:32+08:00\">05\/13\/2026<\/time> <span class=\"byline\"> by <span class=\"author vcard\"><a class=\"url fn n\" href=\"http:\/\/www.puriactives.com\/en\/?author=2\" title=\"View all posts by L, Y\" rel=\"author\">L, Y<\/a><\/span><\/span> \t\t\t\t<\/div><!-- .entry-meta -->\n\t\t\t\n\t\t<\/header><!-- .entry-header -->\n\n\t\t\t\t\t<div class=\"entry-content\">\n\t\t\t\t<h2>The Next-Generation Dermal Architect: Precision-Delivered Triterpenoid for Profound Skin Rejuvenation<\/h2>\n<h2>1. Product Overview<\/h2>\n<p>In the pursuit of ultimate skin longevity, unlocking the full potential of natural triterpenoids has been a long-standing challenge due to their inherent insolubility and limited skin penetration.<\/p>\n<p><b>NanoActive BENZYL URSOLATE <\/b>represents a breakthrough in active ingredient bio-engineering. By synergizing targeted molecular modification (benzyl esterification of ursolic acid) with advanced sub-micron encapsulation technology, we have created a highly bioavailable, potent, and stable anti-aging active. It fundamentally restores Extracellular Matrix (ECM) homeostasis, offering unparalleled firming, anti-wrinkle, and skin-redensifying benefits.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-e31c2abe255e1abb6dd5321cca9d8c24~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778685445-0-0-8e16ce2c1c035b4e3b2b8d40d7236714&amp;bizSceneCode=article_draft&amp;expiration=1778685445&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"785\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-e31c2abe255e1abb6dd5321cca9d8c24~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778688846&amp;auth_key=1778688846-0-0-e140616c69b3375d61d3929e2be8dffc&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2038034316882604221\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-8be696618ee9e271d68b8ebcb3bacb1c~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778688846&amp;auth_key=1778688846-0-0-a08ab84a69348a0dfa79c781d172f471&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>2. The Science: Mechanism of Action<\/h2>\n<p>Standard ursolic acid struggles to cross the stratum corneum. NanoActive BENZYL URSOLATE overcomes this through a dual-action optimization strategy:<\/p>\n<ul>\n<li>Molecular Prodrug Strategy: The attachment of a benzyl group enhances the lipophilicity of the ursolic acid core. Upon penetrating the skin, endogenous epidermal esterases gradually cleave the ester bond, ensuring a sustained and controlled release of the active aglycone directly within the dermal-epidermal junction (DEJ).<\/li>\n<li>Nanostructured Lipid Delivery: Encapsulated within a phospholipid-based nanocarrier system (&lt; 100 nm), the active is shielded from premature degradation. The biomimetic lipid bilayer structure merges seamlessly with the stratum corneum intercellular lipids, facilitating deep transfollicular and intercellular penetration.<\/li>\n<li>ECM Remodeling &amp; Pathway Regulation: Once delivered to the fibroblasts, it acts as a robust inhibitor of Matrix Metalloproteinases (specifically MMP-1 and MMP-9) and human leukocyte elastase (HLE). Simultaneously, it upregulates the synthesis of Collagen I, Collagen III, and ceramides, reversing chronological and photo-induced structural degradation.<\/li>\n<\/ul>\n<h2>3. Key Efficacy Highlights<\/h2>\n<ul>\n<li>Profound Wrinkle Reduction: Visibly diminishes the depth and volume of crow&#8217;s feet and nasolabial folds by restructuring the dermal fiber network.<\/li>\n<li>Enhanced Skin Biomechanics: Significantly improves skin elasticity and firmness, combating gravity-induced sagging.<\/li>\n<li>Barrier Restoration: Stimulates endogenous ceramide production, reinforcing the skin&#8217;s natural lipid barrier and reducing Transepidermal Water Loss (TEWL).<\/li>\n<li>Inflammaging Defense: Exhibits potent anti-inflammatory properties by modulating COX-2 pathways, soothing micro-inflammation that accelerates cellular aging.<\/li>\n<\/ul>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-a9662d7b9752009bffb34be856a6833a~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778685445-0-0-7d04c7f679d5a26c8e64e47bdccf2ee4&amp;bizSceneCode=article_draft&amp;expiration=1778685445&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"750\" data-rawheight=\"1125\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-a9662d7b9752009bffb34be856a6833a~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778688846&amp;auth_key=1778688846-0-0-7ac7a349015fd160e92143c06a9c4696&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2038034316882604221\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-34b2c9031e89fcd3bbb90b91a367cc51~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778688846&amp;auth_key=1778688846-0-0-c13c51f8c576c951341b14b51fe7d75d&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>4. Technical Data &amp; Formulation Guidelines<\/h2>\n<p>Designed with the formulator in mind, NanoActive BENZYL URSOLATE integrates seamlessly into modern cosmetic chassis.<\/p>\n<ul>\n<li>INCI Name: Water, Glycerin, Caprylic\/Capric Triglyceride, Phospholipids, Benzyl Ursolate<\/li>\n<li>Appearance: Translucent to slightly opalescent fluid.<\/li>\n<li>Solubility: Water-dispersible (forms stable nano-emulsion).<\/li>\n<li>Recommended Usage Level: 1.0% \u2013 5.0%<\/li>\n<li>pH Stability Range: 4.5 \u2013 6.5<\/li>\n<li>Formulation Advice: Add during the cooling phase (below 45\u00b0C) to preserve the integrity of the liposomal structures. Avoid high-shear homogenization after addition. Compatible with most emulsifiers, polymers, and other anti-aging actives (e.g., Peptides, Niacinamide).<\/li>\n<\/ul>\n<h2>5. Ideal Applications<\/h2>\n<ul>\n<li>Intensive Anti-Aging Serums &amp; Ampoules<\/li>\n<li>Skin Contouring and Firming Creams<\/li>\n<li>Post-Procedure Barrier Repair Lotions<\/li>\n<li>Premium Eye Care Formulations<\/li>\n<\/ul>\n<p>Elevate your formulations with the precision of science. Contact our technical sales team for in-vivo efficacy data, clinical brochures, and sample requests.<\/p>\n<p><img src=\"https:\/\/picx.zhimg.com\/80\/v2-e23d9ff3e08406b89a6ed2ba5f539959_720w.png\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"608\" data-watermark=\"original\" data-original-src=\"https:\/\/picx.zhimg.com\/v2-e23d9ff3e08406b89a6ed2ba5f539959.png\" data-watermark-src=\"https:\/\/pic1.zhimg.com\/v2-6ceac7fbbc30412642e4fef9a0015526.png\" data-private-watermark-src=\"\" \/><\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div><!-- .entry-content -->\n\t\t\n\t\t\n\t<\/div>\n\n<\/article><!-- #post-1250 -->\n\n\t\n\t\t\n<article id=\"post-1248\" class=\"post-1248 post type-post status-publish format-standard hentry category-news\">\n\n\t\n\t<div class=\"entry-main\">\n\n\t\t\n\t\t<header class=\"entry-header\">\n\t\t\t\n\t\t\t<h1 class=\"entry-title\"><a href=\"http:\/\/www.puriactives.com\/en\/?p=1248\" title=\"Permalink to PuriActives\u00ae Ursolene&#x2122; BZ\" rel=\"bookmark\">PuriActives\u00ae Ursolene&#x2122; BZ<\/a><\/h1>\n\n\t\t\t\t\t\t\t<div class=\"entry-meta\">\n\t\t\t\t\tPosted on <a href=\"http:\/\/www.puriactives.com\/en\/?p=1248\" title=\"22:53\" rel=\"bookmark\"><time class=\"entry-date\" datetime=\"2026-05-13T22:53:20+08:00\">05\/13\/2026<\/time><\/a><time class=\"updated\" datetime=\"2026-05-13T22:53:20+08:00\">05\/13\/2026<\/time> <span class=\"byline\"> by <span class=\"author vcard\"><a class=\"url fn n\" href=\"http:\/\/www.puriactives.com\/en\/?author=2\" title=\"View all posts by L, Y\" rel=\"author\">L, Y<\/a><\/span><\/span> \t\t\t\t<\/div><!-- .entry-meta -->\n\t\t\t\n\t\t<\/header><!-- .entry-header -->\n\n\t\t\t\t\t<div class=\"entry-content\">\n\t\t\t\t<h2>Precision-Engineered Triterpenoid: The Cornerstone of Deep Dermal Rejuvenation &amp; Structural Reconstruction<\/h2>\n<h2>The Botanical Bottleneck<\/h2>\n<p>Natural pentacyclic triterpenes like Ursolic Acid possess exceptional biological activities, but face severe cosmetic limitations:<\/p>\n<p>Extremely poor lipophilicity restricts formulation versatility.<\/p>\n<p>Low skin penetration limits clinical bioavailability.<\/p>\n<p>High propensity to crystallize destabilizes emulsions.<\/p>\n<p>The Solution: By introducing a benzyl group, we fundamentally shift the molecule&#8217;s partition coefficient, creating a highly bioavailable, oil-soluble powerhouse.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-8c6b13f607c938d4859a1e9c42cb467b~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778683894-0-0-d805f3664662bb57aea0f010447755f3&amp;bizSceneCode=article_draft&amp;expiration=1778683894&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"879\" data-rawheight=\"622\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-8c6b13f607c938d4859a1e9c42cb467b~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-3c438a4dc826827e0fe9fa5ed19dbea2&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-bbde791795275bc41295e10b6124ead2~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-4b19d53d80b947cfd005bc3d3d9b0f1d&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Mechanism of Action<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-e4aaf86ab6878f836b2a62f38c400c34~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778683894-0-0-f3586c3f678bace0c1d4717f5ae43a03&amp;bizSceneCode=article_draft&amp;expiration=1778683894&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"391\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-e4aaf86ab6878f836b2a62f38c400c34~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-43367c4ce59fff14139ed25bb86717e6&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-7ddf4ab5eccea4e0d7958a69a2fcb0cc~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-bb6c637bfa4e1830dd7da0a32c98d357&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Bioavailability Shift<\/h2>\n<p>The structural transformation from Ursolic Acid to Ursolene&#x2122; BZ is rooted in a fundamental alteration of the lipid-water partition coefficient.<\/p>\n<p>This precise structural modification transforms a traditional botanical extract into a pharmaceutical-grade, oil-soluble active that seamlessly crosses the stratum corneum to reach deep dermal targets.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-9a36d37c6d7a288a385f33c2dae60314~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778683894-0-0-cd9b78436b619d6e739ae203fa720b2a&amp;bizSceneCode=article_draft&amp;expiration=1778683894&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1055\" data-rawheight=\"254\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-9a36d37c6d7a288a385f33c2dae60314~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-00426cdaa904bfb3e32816081b5f9041&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-0db26ca095137c84e849e8f8cf82450d~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-502950e9cee4a187e6dae0ef2c4e9ecf&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>In Vitro Efficacy<\/h2>\n<h2>Dermal Architecture Support<\/h2>\n<p>Our rigorous efficacy testing matrix demonstrates statistically significant improvements compared to vehicle and unmodified free ursolic acid controls.<\/p>\n<p>Tested on primary human fibroblasts at 10 \u03bcM concentration (p &lt; 0.01). The dramatic reduction in UV-induced elastase activity ensures the preservation of the skin&#8217;s vital recoil capacity.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-eb3ab9c2fb1740943b3e9909d8ff2b07~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778683894-0-0-754f5e9a3faf58fe911b91164f6d9132&amp;bizSceneCode=article_draft&amp;expiration=1778683894&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"764\" data-rawheight=\"700\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-eb3ab9c2fb1740943b3e9909d8ff2b07~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-8f3a1075f08ad09c6cef3d354fdd0780&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-7d93be552f894f917b1c2ede36e5a66e~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-8eaf0a61148dd23c9a76dab0c7a1ab30&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>In Vivo Clinical Results<\/h2>\n<p>A double-blind, placebo-controlled clinical study on 30 female volunteers (aged 45-65), applying a 0.2% PuriActives\u00ae Ursolene&#x2122; BZ cream twice daily for 28 days.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-4f3e43a967cf6d3a0958a5b636981da5~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778683894-0-0-3af41ff284effcb938280c7da451b54c&amp;bizSceneCode=article_draft&amp;expiration=1778683894&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"267\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-4f3e43a967cf6d3a0958a5b636981da5~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-3b206ee65fe94f3b9177e58d82c0d9c3&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-ee4bc083a8ae6cff2640f4982fc1426c~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-edb40b2121c591c3d25c7038aaea7acf&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Stability Comparison<\/h2>\n<p>Comparative analysis of formulation stability and lipid solubility scores (measured as a relative percentage of an ideal oil-soluble active profile).<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-7476c95ba7f61bb97f0f3c01828797dc~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778683894-0-0-f13149565d6f415641c2a1534dae33aa&amp;bizSceneCode=article_draft&amp;expiration=1778683894&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"330\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-7476c95ba7f61bb97f0f3c01828797dc~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-568129933584e0a27103da1c829c39e8&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-55f845b9ec37ebecc55d6ab2bcf7652e~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-1d03ef384d91fe5353ddcc68de62fbf7&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Technical Guidelines<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-80ad58b2b2907bca646fcb07d7bb59f8~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778683894-0-0-356dbada741a8677e9ede876669dbcbb&amp;bizSceneCode=article_draft&amp;expiration=1778683894&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"486\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-80ad58b2b2907bca646fcb07d7bb59f8~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-0b4aab188ba589cd29cd0ba361de6cf7&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-e170acf4e8c8a245c60313cd24e84be7~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-cf1f54ed6b0938f3750f1a86c0bef250&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Sustainable Sourcing<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-cb746e56f0f2429e979d8876b95d5944~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778683894-0-0-d2b1bc069515ead4a32310d9a9a4d1ef&amp;bizSceneCode=article_draft&amp;expiration=1778683894&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"482\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-cb746e56f0f2429e979d8876b95d5944~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-d6143e3eeabfd7daef8fbcaceddb3915&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-a7e1aced591f64d7efb7be4fd08b830e~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-b5243872aa1ba9cd658972cf56648f47&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Target Applications<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-6661c58cfd526bcc9251395bf13ec25d~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778683894-0-0-7ecec78433bf1e33febe335670fd8b6b&amp;bizSceneCode=article_draft&amp;expiration=1778683894&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"546\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-6661c58cfd526bcc9251395bf13ec25d~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-27c53e88f845e0c1bf7bb103e5ac36c2&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-466711ddd78b8f7c6faee7c0a0f9a38b~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778687243&amp;auth_key=1778687243-0-0-9ec99bd187d4f8ed7c78b9e03afb1181&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>The perfect synergy of a naturally derived core and rational structural design, bridging the gap between pharmaceutical-grade precision and cosmetic applicability.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-e23d9ff3e08406b89a6ed2ba5f539959~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778683894-0-0-7fb6b570f51b21a1cb48f24870671f0b&amp;bizSceneCode=article_draft&amp;expiration=1778683894&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"608\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-e23d9ff3e08406b89a6ed2ba5f539959~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778687242&amp;auth_key=1778687242-0-0-6770b9747cc49fa6dae067ad50b7c4f7&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2038027592738006745\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-6ceac7fbbc30412642e4fef9a0015526~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778687243&amp;auth_key=1778687243-0-0-a1bf9ed60d21a706536d6e52179ef2e6&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div><!-- .entry-content -->\n\t\t\n\t\t\n\t<\/div>\n\n<\/article><!-- #post-1248 -->\n\n\t\n\t\t\n<article id=\"post-1246\" class=\"post-1246 post type-post status-publish format-standard hentry category-news tag-anti-free-radicals tag-nano-liposomal-haematococcus-astaxanthin-anti-oxidation tag-resists-uva\">\n\n\t\n\t<div class=\"entry-main\">\n\n\t\t\n\t\t<header class=\"entry-header\">\n\t\t\t\n\t\t\t<h1 class=\"entry-title\"><a href=\"http:\/\/www.puriactives.com\/en\/?p=1246\" title=\"Permalink to PuriActives\u00ae Ursolene&#x2122; BZ (Benzyl Ursolate)\" rel=\"bookmark\">PuriActives\u00ae Ursolene&#x2122; BZ (Benzyl Ursolate)<\/a><\/h1>\n\n\t\t\t\t\t\t\t<div class=\"entry-meta\">\n\t\t\t\t\tPosted on <a href=\"http:\/\/www.puriactives.com\/en\/?p=1246\" title=\"19:55\" rel=\"bookmark\"><time class=\"entry-date\" datetime=\"2026-05-12T19:55:44+08:00\">05\/12\/2026<\/time><\/a><time class=\"updated\" datetime=\"2026-05-12T19:55:44+08:00\">05\/12\/2026<\/time> <span class=\"byline\"> by <span class=\"author vcard\"><a class=\"url fn n\" href=\"http:\/\/www.puriactives.com\/en\/?author=2\" title=\"View all posts by L, Y\" rel=\"author\">L, Y<\/a><\/span><\/span> \t\t\t\t<\/div><!-- .entry-meta -->\n\t\t\t\n\t\t<\/header><!-- .entry-header -->\n\n\t\t\t\t\t<div class=\"entry-content\">\n\t\t\t\t<h2>Precision-Engineered Triterpenoid: The Cornerstone of Deep Dermal Rejuvenation &amp; Structural Reconstruction<\/h2>\n<h2>1. Product Overview<\/h2>\n<p>While natural pentacyclic triterpenes (like Ursolic Acid) are renowned for their exceptional biological activities, their cosmetic application has historically been bottlenecked by extremely poor lipophilicity, low skin penetration, and formulation instability (propensity to crystallize).<\/p>\n<p>Enter PuriActives\u00ae Ursolene&#x2122; BZ (INCI: Benzyl Ursolate). By introducing a benzyl group to the ursolic acid backbone, we have fundamentally shifted the molecule&#8217;s partition coefficient ( log P). This precise structural modification transforms a traditional botanical extract into a highly bioavailable, oil-soluble powerhouse. It precisely targets the Extracellular Matrix (ECM) architecture, offering a definitive solution for intrinsic\/extrinsic aging, loss of elasticity, and compromised skin barriers.<\/p>\n<p>The Core Edge: The perfect synergy of a naturally derived core and rational structural design, bridging the gap between pharmaceutical-grade precision and cosmetic applicability.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-a835808829fc1b08d0f2207ea0733901~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778587040-0-0-d813b8c6a72dcff0a5a9016e706d932c&amp;bizSceneCode=article_draft&amp;expiration=1778587040&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"733\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-a835808829fc1b08d0f2207ea0733901~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778590124&amp;auth_key=1778590124-0-0-bbde99b3074356b191875becf6f07dcc&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2037620243862901844\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-5b0ee8c31f7007a9ae314acd52814831~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778590124&amp;auth_key=1778590124-0-0-c79287ebc0f27a394fe3aa3cb1a7d08c&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>2. Key Biological Pathways &amp; Mechanism of Action<\/h2>\n<p>PuriActives\u00ae Ursolene&#x2122; BZ operates through a multi-target mechanism, mitigating tissue senescence at the cellular level:<\/p>\n<p>MMP Modulation &amp; ECM Protection: Acts as a potent competitive inhibitor of Matrix Metalloproteinases (specifically MMP-1 and MMP-9), halting the enzymatic degradation cascade of collagen and elastin networks.<\/p>\n<p>Fibroblast Activation via TGF-\u03b2 Pathway: Stimulates the transforming growth factor-beta (TGF-\u03b2) signaling pathway, upregulating COL1A1 and COL3A1 gene expression to drive the de novo synthesis of structural proteins.<\/p>\n<p>Inflammaging Mitigation: Suppresses the cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) pathways, interrupting the chronic micro-inflammatory cascades that accelerate tissue aging.<\/p>\n<p>Epidermal Lipid Biosynthesis: Upregulates serine palmitoyltransferase (SPT) activity, driving endogenous ceramide production to fortify the stratum corneum barrier.<\/p>\n<h2>3. Proven Efficacy (In Vitro &amp; In Vivo Highlights)<\/h2>\n<p>Our rigorous efficacy testing matrix demonstrates statistically significant improvements compared to vehicle and unmodified free ursolic acid controls.<\/p>\n<p>In Vitro: Dermal Architecture Support<\/p>\n<ul>\n<li>+ 42% Increase in Pro-collagen I synthesis (Primary human fibroblasts, at 10\u03bcM, ).<\/li>\n<li>&#8211; 65% Reduction in UV-induced elastase activity, effectively preserving skin recoil capacity.<\/li>\n<\/ul>\n<p>In Vivo Clinical Study: Facial Micro-Topography (28-Day Study)<\/p>\n<p>A double-blind, placebo-controlled clinical study on 30 female volunteers (aged 45-65), applying a 0.2% PuriActives\u00ae Ursolene&#x2122; BZ cream twice daily.<\/p>\n<p>\u25cf Wrinkle Depth (Ra): Significant reduction of 21.4% in the periocular region.<\/p>\n<p>\u25cf Skin Density: Ultrasound imaging revealed a +15% increase in dermal echogenicity, indicating structural redensification of the dermis.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-002669c1ad8a8f1ee3a5fcb845988048~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778587040-0-0-1a6ab4cb16d3e34247e697f804f196cc&amp;bizSceneCode=article_draft&amp;expiration=1778587040&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"721\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-002669c1ad8a8f1ee3a5fcb845988048~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778590123&amp;auth_key=1778590123-0-0-6d46a3220b801222b36e028d9ae78c93&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2037620243862901844\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-7b8bd53aebf38f1b038a7447d3846dcd~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778590123&amp;auth_key=1778590123-0-0-a81969833564cca798bf6ef84e81bfb2&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>4. Formulation &amp; Technical Guidelines<\/h2>\n<p>PuriActives\u00ae Ursolene&#x2122; BZ is engineered for the ultimate formulator experience. Its esterified structure completely circumvents the notorious crystallization issues of free ursolic acid, enabling the creation of highly stable, cosmetically elegant emulsions.<\/p>\n<p>\u25cf INCI Name: Benzyl Ursolate<\/p>\n<p>\u25cf Appearance: White to off-white crystalline powder<\/p>\n<p>\u25cf Solubility: Soluble in cosmetic esters (e.g., Caprylic\/Capric Triglyceride, Squalane), ethanol, and glycols. Insoluble in water.<\/p>\n<p>\u25cf Recommended Usage Level: 0.05% \u2013 0.30%<\/p>\n<p>\u25cf Formulation Integration: Add to the heated oil phase ( 70~80\u2103 ) and stir until fully dissolved before emulsification.<\/p>\n<p>\u25cf Optimal pH Range: 4.5 \u2013 6.5<\/p>\n<h2>5. Sustainability &amp; Purity<\/h2>\n<p>PuriActives\u00ae Ursolene&#x2122; BZ is derived from upcycled apple pomace and rosemary extract precursors, synthesized via a highly efficient, atom-economical esterification process. We guarantee an ultra-high purity active (HPLC \uff1e 95%) while minimizing our environmental footprint.<\/p>\n<p>Recommended Applications:<\/p>\n<p>\u25cf Premium Anti-Aging Night Creams<\/p>\n<p>\u25cf Intensive Barrier Repair Serums<\/p>\n<p>\u25cf Dermo-cosmetics (Post-Procedure Care)<\/p>\n<p>\u25cf Sun Recovery &amp; &#8220;Anti-Inflammaging&#8221; Formulations<\/p>\n<p><img src=\"https:\/\/pic1.zhimg.com\/80\/v2-784a7abdf5a4ee03a4545155ca8b6a16_720w.png\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"405\" data-watermark=\"original\" data-original-src=\"https:\/\/pica.zhimg.com\/v2-784a7abdf5a4ee03a4545155ca8b6a16.png\" data-watermark-src=\"https:\/\/pica.zhimg.com\/v2-dab2e47a3203f96cc5c28ce277dc3693.png\" data-private-watermark-src=\"\" \/><\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div><!-- .entry-content -->\n\t\t\n\t\t\n\t<\/div>\n\n<\/article><!-- #post-1246 -->\n\n\t\n\t\t\n<article id=\"post-1243\" class=\"post-1243 post type-post status-publish format-standard hentry category-news tag-bioactive-ingredients tag-nano-liposomal-haematococcus-astaxanthin-anti-oxidation\">\n\n\t\n\t<div class=\"entry-main\">\n\n\t\t\n\t\t<header class=\"entry-header\">\n\t\t\t\n\t\t\t<h1 class=\"entry-title\"><a href=\"http:\/\/www.puriactives.com\/en\/?p=1243\" title=\"Permalink to NanoActive DHM\" rel=\"bookmark\">NanoActive DHM<\/a><\/h1>\n\n\t\t\t\t\t\t\t<div class=\"entry-meta\">\n\t\t\t\t\tPosted on <a href=\"http:\/\/www.puriactives.com\/en\/?p=1243\" title=\"23:59\" rel=\"bookmark\"><time class=\"entry-date\" datetime=\"2026-05-10T23:59:24+08:00\">05\/10\/2026<\/time><\/a><time class=\"updated\" datetime=\"2026-05-10T23:59:24+08:00\">05\/10\/2026<\/time> <span class=\"byline\"> by <span class=\"author vcard\"><a class=\"url fn n\" href=\"http:\/\/www.puriactives.com\/en\/?author=2\" title=\"View all posts by L, Y\" rel=\"author\">L, Y<\/a><\/span><\/span> \t\t\t\t<\/div><!-- .entry-meta -->\n\t\t\t\n\t\t<\/header><!-- .entry-header -->\n\n\t\t\t\t\t<div class=\"entry-content\">\n\t\t\t\t<h2>NanoActive DHM Epigenetic Youth Restorer &amp; DNA Methylation Inhibitor<\/h2>\n<h2>1. PRODUCT IDENTIFICATION<\/h2>\n<ul>\n<li>Product Name: NanoActive DHM<\/li>\n<li>Trade Name: NanoActive DHM by PuriPharm<\/li>\n<li>INCI Name: Water, Glycerin, Caprylic\/Capric Triglyceride, Ampelopsis Grossedentata Extract, Phospholipids, Tocopheryl Acetate.<\/li>\n<li>Botanical Source of Active: Ampelopsis grossedentata(Vine Tea)<\/li>\n<li>Active Content: 9.5% &#8211; 10.5% (Ampelopsis Grossedentata Extract)<\/li>\n<\/ul>\n<h2>2. PRODUCT DESCRIPTION<\/h2>\n<p><b>NanoActive DHM <\/b>represents a paradigm shift in epigenetic anti-aging. Developed by PuriPharm Co. Ltd., it is the industry&#8217;s first cosmetically viable DNA methylation inhibitor. Utilizing advanced nanoliposomal technology, highly purified Dihydromyricetin (DHM) is encapsulated in a biomimetic phospholipid bilayer. This sophisticated delivery system overcomes the inherent instability and poor skin penetration of DHM, allowing for targeted delivery to the deep epidermis and dermis, fundamentally reversing cellular aging at the genetic transcription level.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-3a78be551c13a8b1b667ffe993dc6b88~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778428788-0-0-8a8c6acdc6a93cf13dee574892060cc5&amp;bizSceneCode=article_draft&amp;expiration=1778428788&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"748\" data-rawheight=\"1125\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-3a78be551c13a8b1b667ffe993dc6b88~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778432149&amp;auth_key=1778432149-0-0-60640b73f9b18c5155a2a8067f686e55&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2036957654174709233\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-8581f13eb14fe913b362f204c1b65293~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778432149&amp;auth_key=1778432149-0-0-2ba0227e907e80484316a6a71b79fa21&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>3. MECHANISM OF ACTION<\/h2>\n<p>Environmental stressors (UV, pollution) and intrinsic aging lead to <b>hypermethylation <\/b>of DNA, which functionally &#8220;silences&#8221; essential youth and structural genes.<\/p>\n<ul>\n<li>Epigenetic Reversal: NanoActive DHM acts as a potent DNA methylation inhibitor, effectively removing age-induced methyl tags.<\/li>\n<li>Gene Reactivation: By modulating over 10,000 methylation sites, it reactivates silenced genes associated with the Extracellular Matrix (ECM), signal transduction, and autophagy.<\/li>\n<li>Targeted Delivery: The 50-150 nm liposomal spheres ensure enhanced transdermal absorption and a sustained-release profile, maximizing biological availability and minimizing potential irritation.<\/li>\n<\/ul>\n<h2>4. TECHNICAL SPECIFICATIONS<\/h2>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-3aef2f4d2fbd50917d5c9fbb7916c0f7~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778428788-0-0-67659149315d4e28de03038ad5e55405&amp;bizSceneCode=article_draft&amp;expiration=1778428788&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"677\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-3aef2f4d2fbd50917d5c9fbb7916c0f7~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778432149&amp;auth_key=1778432149-0-0-46508c683f7dbc7b45d595c8ed30d2d0&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-62641cb9ab5401efc6883a2f5b2e40e3~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778432149&amp;auth_key=1778432149-0-0-7b7805f18941c0dd32b694172c92c424&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>5. EFFICACY &amp; CLINICAL DATA SUMMARY<\/h2>\n<ul>\n<li>Transcriptomic Upregulation: Significantly upregulates key structural genes including COL6A1 (Collagen Type VI), ITGB6, ITGA5, and VCL, restoring cellular anchorage and tissue firmness.<\/li>\n<li>3D Skin Equivalent Model: In a 6-week in vitrostudy utilizing 20\u00b5M DHM on mature 3D skin models, NanoActive DHM effectively reversed epidermal thinning. Epidermal thickness increased from 30\u00b5m (untreated mature control) to ~50\u00b5m, closely mirroring the baseline of young skin models (60\u00b5m). Statistical significance achieved (p = 0.00064).<\/li>\n<\/ul>\n<h2>6. FORMULATION GUIDELINES<\/h2>\n<p>NanoActive DHM is designed for ease of use in premium cosmetic formulations.<\/p>\n<ul>\n<li>Recommended Usage Level: 1.0% \u2013 5.0%<\/li>\n<li>Incorporation Phase: Add to the aqueous phase or during the cooling phase (below 45\u00b0C) for emulsions to maintain liposomal integrity.<\/li>\n<li>pH Compatibility: Stable within a final formulation pH range of 4.5 \u2013 7.5.<\/li>\n<li>Incompatibilities: Avoid high concentrations of strong ionic surfactants or extreme ethanol levels (&gt;20%) which may disrupt the lipid bilayer.<\/li>\n<li>Processability: Do not subject to intense, prolonged shear force (homogenization &gt; 3000 rpm for extended periods) after incorporation.<\/li>\n<\/ul>\n<h2>7. TARGET APPLICATIONS<\/h2>\n<ul>\n<li>Premium Anti-Aging Skincare: Serums, night creams, and eye treatments targeting chronological aging and photoaging.<\/li>\n<li>Medical Aesthetics Post-Care: Restorative formulations designed to prolong the effects of clinical treatments by maintaining epigenetic cellular health.<\/li>\n<li>Preventative Aging: Solutions targeting millennials\/Gen-Z exposed to urban pollution, stress, and lifestyle-induced epigenetic damage.<\/li>\n<\/ul>\n<h2>8. STORAGE &amp; SHELF LIFE<\/h2>\n<ul>\n<li>Storage Conditions: Store in a cool, dry place away from direct sunlight. Recommended storage temperature: 4\u00b0C &#8211; 25\u00b0C. Do not freeze. Keep containers tightly sealed when not in use.<\/li>\n<li>Shelf Life: 24 months from the date of manufacture under optimal storage conditions.<\/li>\n<\/ul>\n<p>Disclaimer: The information provided herein is based on our current knowledge and rigorous scientific testing. It is intended for informational purposes for cosmetic professionals and formulators. It is the responsibility of the formulator to ensure the stability, safety, and regulatory compliance of the final consumer product.<\/p>\n<p><b>PuriPharm Co. Ltd.<\/b>Pioneering Epigenetic Skincare SolutionsWebsite: www.puriactives.com | Email: service@puripharm.com<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/picx.zhimg.com\/80\/v2-784a7abdf5a4ee03a4545155ca8b6a16_720w.png\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"405\" data-watermark=\"original\" data-original-src=\"https:\/\/pic1.zhimg.com\/v2-784a7abdf5a4ee03a4545155ca8b6a16.png\" data-watermark-src=\"https:\/\/picx.zhimg.com\/v2-dab2e47a3203f96cc5c28ce277dc3693.png\" data-private-watermark-src=\"\" \/><\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div><!-- .entry-content -->\n\t\t\n\t\t\n\t<\/div>\n\n<\/article><!-- #post-1243 -->\n\n\t\n\t\t\n<article id=\"post-1238\" class=\"post-1238 post type-post status-publish format-standard hentry category-news tag-anti-free-radicals tag-nano-liposomal-haematococcus-astaxanthin-anti-oxidation\">\n\n\t\n\t<div class=\"entry-main\">\n\n\t\t\n\t\t<header class=\"entry-header\">\n\t\t\t\n\t\t\t<h1 class=\"entry-title\"><a href=\"http:\/\/www.puriactives.com\/en\/?p=1238\" title=\"Permalink to NanoActive DHM\" rel=\"bookmark\">NanoActive DHM<\/a><\/h1>\n\n\t\t\t\t\t\t\t<div class=\"entry-meta\">\n\t\t\t\t\tPosted on <a href=\"http:\/\/www.puriactives.com\/en\/?p=1238\" title=\"23:37\" rel=\"bookmark\"><time class=\"entry-date\" datetime=\"2026-05-06T23:37:59+08:00\">05\/06\/2026<\/time><\/a><time class=\"updated\" datetime=\"2026-05-06T23:38:32+08:00\">05\/06\/2026<\/time> <span class=\"byline\"> by <span class=\"author vcard\"><a class=\"url fn n\" href=\"http:\/\/www.puriactives.com\/en\/?author=2\" title=\"View all posts by L, Y\" rel=\"author\">L, Y<\/a><\/span><\/span> \t\t\t\t<\/div><!-- .entry-meta -->\n\t\t\t\n\t\t<\/header><!-- .entry-header -->\n\n\t\t\t\t\t<div class=\"entry-content\">\n\t\t\t\t<section data-layout-id=\"0\" data-pm-slice=\"0 0 []\">Scientific Breakthrough: Epigenetic Anti-AgingDeveloped byPuriPharmCo. Ltd.<\/p>\n<h2>1. Epigenetics and Skin Aging<\/h2>\n<h2>What is Epigenetics?<\/h2>\n<p>Epigenetics is the science studying how lifestyle and environmental factors influence gene expression.<\/p>\n<p>This process occurs without changing the underlying DNA sequence.<\/p>\n<p>Instead, it alters gene activity by turning genes &#8220;on&#8221; or &#8220;off&#8221; based on external stimuli.<\/p>\n<p>It provides a profound new target for anti-aging interventions by addressing the root causes of cellular decline.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-c481fd016bcefcb40cba891646fac13f~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-7f40cfd319fc60dd70da1489aaca3d3b&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"847\" data-rawheight=\"613\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-c481fd016bcefcb40cba891646fac13f~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-d495177523e831ee03b3a5a18a7dbe33&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2035502486463701166\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-0b6693512bdeda1ede2942f9c05956d8~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085211&amp;auth_key=1778085211-0-0-59e1105f03883df0c0ae17ca343e6ad5&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>The Identical Twins Study<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-37be7817dcdf76fb4e97db04ea82dd1d~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-2b68ac499280ddd4d18ba05075b86649&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"317\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-37be7817dcdf76fb4e97db04ea82dd1d~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-4892bafa8183c7aad336dd0d697bf9a5&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-28d83369b0dc155cf16200eed0998169~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-88407d44b71e83c21ca42f26889eb31b&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Primary Drivers of Skin Aging<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-74b4799ba0075bb03163dd60813bf280~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-440f8bfad67a03b29673bc1055093137&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"325\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-74b4799ba0075bb03163dd60813bf280~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-0629d2582edd409e0120cbc18e1b6f80&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-39f109b608cd6b7e52b3f86c9d40d49f~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-34febbd8a444ec73cdfe78a7a1aab438&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>The Process of DNA Methylation<\/h2>\n<p>Lifestyle and environmental factors influence gene expression primarily through DNA methylation.<\/p>\n<p>Methyl groups (epigenetic factors) attach to the DNA molecule.<\/p>\n<p>These methylation marks can activate or, more commonly in aging, improperly repress or &#8220;silence&#8221; specific genes.<\/p>\n<p>This makes the DNA inaccessible to the machinery that keeps cells youthful and functional.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-4cd8fa52ef6fe15091283bf693396b30~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-95e60952b3d8062c22b6335715246f3c&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"847\" data-rawheight=\"613\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-4cd8fa52ef6fe15091283bf693396b30~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-75c0debe29ced7781572c0d6c92ba0df&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-89626e13dbae9b1df62ab8776c9e18e2~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-1c0d2e1b2062d830e68b69eddbbf012a&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Hypermethylation and Aging<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-e4cc44e474434f36ea5db63919651346~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-7f9e0dc207b5aa3a62e5865f30ccb210&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"591\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-e4cc44e474434f36ea5db63919651346~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-d912c0b33728f0f4f8aad0a24750e45f&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-07918b10c84265de7f44c924314b2858~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-a3d061e28e317c084db5b50c80fae5c1&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>2. The DHM Breakthrough<\/h2>\n<p>Introducing Dihydromyricetin: The world&#8217;s first cosmetic DNA methylation inhibitor.<\/p>\n<h2>A Global Innovation<\/h2>\n<p>Dihydromyricetin (DHM)\uff1a<\/p>\n<p>NanoActive DHM features Dihydromyricetin, globally recognized as the first cosmetic ingredient scientifically proven to inhibit DNA methylation. This represents a paradigm shift, leading a completely new direction in epigenetic anti-aging interventions.<\/p>\n<h2>Mechanism of Action<\/h2>\n<p>Inhibit Methylation: DHM acts directly at the genetic level to regulate and inhibit the excessive DNA methylation patterns that accumulate over time.<\/p>\n<p>Reactivate Youth Genes: By removing these inhibitory methyl tags, DHM successfully reactivates silenced youth genes.<\/p>\n<p>Restore Vitality: This fundamentally delays cellular aging by returning skin cells to their peak functional state, rather than just treating surface symptoms.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-e9752ed026d39bcde440ce5c3439ead5~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-375a27baabaed82741dc49cb4c15989f&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"835\" data-rawheight=\"993\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-e9752ed026d39bcde440ce5c3439ead5~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-df155b2f63b2518c59d3b2247af39dd7&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-b32807086f0db8205332adc15edf4f24~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-66a37ff3bae0c166b6622b3c024464e0&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Natural Plant Source<\/h2>\n<p>NanoActive DHM is extracted exclusively from Ampelopsis Grossedentata, commonly known as Vine Tea.<\/p>\n<p>It belongs to the Vitaceae family, Ampelopsis genus.<\/p>\n<p>This specific plant is exceptionally rich in naturally occurring Dihydromyricetin.<\/p>\n<p>It provides a clean, sustainable, and highly potent botanical source for epigenetic anti-aging formulations.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-a665903c03c7421d9f98b4e0f18fa156~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-8722298af2f887e1ee48f8b7b982aeb3&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"847\" data-rawheight=\"613\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-a665903c03c7421d9f98b4e0f18fa156~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-15925c433d3dee9f921b2ab67034b454&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2035502486463701166\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-b8343e4250bd59dd0ab3838ed02c6536~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-aaeb0fcd855babe4d62ed57b4a71dd90&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Cultivation &amp; Extraction<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-3ef41298084e7303f4bf7ded4d64d0b8~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-15e2a4557cc2dde6b85ca25a36c0e022&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"448\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-3ef41298084e7303f4bf7ded4d64d0b8~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-32f111924ae41022a399428df61df80b&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-e198b4da4cb38f57d2f11e7cf0a0c14a~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-504b750f327b9c2b3501c5eedf74bc8f&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>3. Advanced Nanoliposome Technology<\/h2>\n<h2>Nanoliposome Principles<\/h2>\n<p>Definition: Nanoliposomes are microscopic vesicles composed of phospholipid bilayers that perfectly mimic the human cell membrane structure.<\/p>\n<p>Average Size: Ranging from 10 to 50 nm, they are perfectly sized to penetrate the skin barrier effectively.<\/p>\n<p>Encapsulation: They possess a high drug entrapment efficiency, capable of securely encapsulating both hydrophobic and hydrophilic active ingredients like DHM.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-f11e53cdbab1f052dc17dbeea2677c8f~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-37babdc4820da74e1973f1919b1e558d&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"961\" data-rawheight=\"1125\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-f11e53cdbab1f052dc17dbeea2677c8f~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085211&amp;auth_key=1778085211-0-0-d8000d549fe818f79c294bbc4efe72f2&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2035502486463701166\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-8825beea483b150bdf5171d363a2b377~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085212&amp;auth_key=1778085212-0-0-8867510cff3e9ba9cd0a526c16a2f768&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Technology Advantages<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-d0ccfc85d61023a14cf6e2fb74786bb3~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-7309292b097ae6bf616f3a4c11ffd1fe&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"375\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-d0ccfc85d61023a14cf6e2fb74786bb3~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-158f3dedfa9e0d0c646a0a7a4f65355f&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-d0b0eff4c022f42c7a5f077d8cf4f5e1~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-65f731359bc93edf92c2b205b4c7ad62&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>The Dual Breakthrough<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-c57dc0df1df9545832e21ffe5286349e~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-c181a2235179e7e6bbf040bcfc106d52&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"307\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-c57dc0df1df9545832e21ffe5286349e~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-85155ad7c53f946e6f993a748d1edf6a&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-9e255e2edd88ebb9621f40e8b5891645~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-04f776617129ce38f602abe749636f47&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>4. Clinical Efficacy and Validation<\/h2>\n<h2>DNA Methylation Impact<\/h2>\n<h2>Reversing the Clock<\/h2>\n<p>Under experimental conditions (20\u00b5M DHM over 6 weeks on a skin equivalent model), DHM treatment significantly affected over 10,000 methylation sites. It successfully induced a young epidermal DNA methylation pattern, restoring youthful epigenetic characteristics.<\/p>\n<h2>Epidermal Structure Improvement<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-e35d4ee95be739473c7098824119fcd2~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-ba9970719a91affad6b4382b3bc362d4&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"481\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-e35d4ee95be739473c7098824119fcd2~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-f73da744c7d2bf874808f5311bad2e6c&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-5e6e9ab4289b6d0b011bb7ff1637865d~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-3d4d8283e622b4f0dc5a5c45862bb239&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Reactivation of Youth Genes<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-71d7328b9e321d9af16e58807cbc308b~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-ea6a45bd0f2c26e4811630cdffed43a1&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"616\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-71d7328b9e321d9af16e58807cbc308b~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-1fd2543f7c78f4f7d206eeaf5474742f&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-ea9a121e7aceb573cdab78479606e022~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-8be57a41af90a7c138203fb8cf8c00c3&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>5. Market Application &amp; Value<\/h2>\n<h2>Competitive Advantage<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-f1e24741db114c7d85179aa15dcef701~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-68139e3761f48dfb677b1a66fe5adcbe&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"485\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-f1e24741db114c7d85179aa15dcef701~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-3382a0ff0cabb643bf65f86a3ac5ee6a&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-77c0e571eb938f8b75c23ba6d0d0c2c2~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-0e14569e6552ac83aed13f1978ede57b&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2>Target Market &amp; Applications<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-2548800d7db52658bb41f03834973491~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1778081875-0-0-8d962ae3a70799a500e04103e46d2bb3&amp;bizSceneCode=article_draft&amp;expiration=1778081875&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"361\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-2548800d7db52658bb41f03834973491~resize:0:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-f11bc2e5b964d7a40805bf198c3239e1&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-03d6267952b9ecc9d32d3cff73680734~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1778085210&amp;auth_key=1778085210-0-0-54bcd1bb9e4a98e121e80f88f3bd9b99&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><img src=\"https:\/\/pica.zhimg.com\/80\/v2-784a7abdf5a4ee03a4545155ca8b6a16_720w.png\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"405\" data-watermark=\"original\" data-original-src=\"https:\/\/pic1.zhimg.com\/v2-784a7abdf5a4ee03a4545155ca8b6a16.png\" data-watermark-src=\"https:\/\/picx.zhimg.com\/v2-dab2e47a3203f96cc5c28ce277dc3693.png\" data-private-watermark-src=\"\" \/><\/p>\n<\/section>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div><!-- .entry-content -->\n\t\t\n\t\t\n\t<\/div>\n\n<\/article><!-- #post-1238 -->\n\n\t\n\t\t\n<article id=\"post-1236\" class=\"post-1236 post type-post status-publish format-standard hentry category-news tag-anti-dandruff tag-smoothness\">\n\n\t\n\t<div class=\"entry-main\">\n\n\t\t\n\t\t<header class=\"entry-header\">\n\t\t\t\n\t\t\t<h1 class=\"entry-title\"><a href=\"http:\/\/www.puriactives.com\/en\/?p=1236\" title=\"Permalink to NanoActive&#x2122; DCP Advanced Liposomal Dimethylmethoxy Chromanyl Palmitate\" rel=\"bookmark\">NanoActive&#x2122; DCP Advanced Liposomal Dimethylmethoxy Chromanyl Palmitate<\/a><\/h1>\n\n\t\t\t\t\t\t\t<div class=\"entry-meta\">\n\t\t\t\t\tPosted on <a href=\"http:\/\/www.puriactives.com\/en\/?p=1236\" title=\"18:08\" rel=\"bookmark\"><time class=\"entry-date\" datetime=\"2026-05-02T18:08:21+08:00\">05\/02\/2026<\/time><\/a><time class=\"updated\" datetime=\"2026-05-02T18:08:21+08:00\">05\/02\/2026<\/time> <span class=\"byline\"> by <span class=\"author vcard\"><a class=\"url fn n\" href=\"http:\/\/www.puriactives.com\/en\/?author=2\" title=\"View all posts by L, Y\" rel=\"author\">L, Y<\/a><\/span><\/span> \t\t\t\t<\/div><!-- .entry-meta -->\n\t\t\t\n\t\t<\/header><!-- .entry-header -->\n\n\t\t\t\t\t<div class=\"entry-content\">\n\t\t\t\t<h2><b>Next-Generation Targeted Delivery for Flawless, Radiant Skin<\/b><\/h2>\n<h2><b>Product Overview<\/b><\/h2>\n<p>In the pursuit of safe and highly effective skin depigmentation, the delivery system is just as crucial as the active molecule itself. <b>NanoActive&#x2122; DCP<\/b> represents a paradigm shift in cosmetic skin brightening. By encapsulating the potent, photo-protective brightening agent\u2014Dimethylmethoxy Chromanyl Palmitate\u2014within an advanced nanoscale liposomal carrier, we have solved the traditional challenges of cutaneous penetration and active stability.<\/p>\n<p>Designed for premium anti-aging and skin-illuminating formulations, this branded ingredient offers unparalleled bioavailability. It delivers the active compound precisely to the basal layer where melanocytes reside, unleashing peak biological activity at the nanoscale (the <b>NanoActive&#x2122;<\/b> advantage).<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-70d2975b03cb2f1650fedff99f00d87e~resize:1440:q75.jpg?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1777716549-0-0-0b9f47329dd62e6990759d1411a861d7&amp;bizSceneCode=article_draft&amp;expiration=1777716549&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"720\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-70d2975b03cb2f1650fedff99f00d87e~resize:0:q75.jpg?source=1f5c5e47&amp;expiration=1777720011&amp;auth_key=1777720011-0-0-ffac230e18453a428f6723f51b5a22b2&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2033970724419937846\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-6e6a7403731bfee91d55a6603460406a~resize:1440:q75.jpg?source=1f5c5e47&amp;expiration=1777720012&amp;auth_key=1777720012-0-0-c8b3a3a8dd632516090060994c559120&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<h2><b>Technical Identity<\/b><\/h2>\n<ul>\n<li><b>Trade Name:<\/b> NanoActive&#x2122; DCP<\/li>\n<li><b>INCI Name:<\/b> Water (and) Glycerin (and) Phospholipids (and) Dimethylmethoxy Chromanyl Palmitate<\/li>\n<li><b>Appearance:<\/b> Translucent to clear pale yellow liquid<\/li>\n<li><b>Solubility:<\/b> Water-dispersible<\/li>\n<li><b>Recommended Usage Level:<\/b> 1.0% &#8211; 5.0%<\/li>\n<\/ul>\n<h2><b>The Science: Mechanism of Action<\/b><\/h2>\n<p>Our proprietary liposomal technology bridges the gap between biological potential and clinical efficacy through a dual-action mechanism:<\/p>\n<h3><b>1. The Active: Precision Tyrosinase Inhibition<\/b><\/h3>\n<p>At the core of <b>NanoActive&#x2122; DCP<\/b> is Dimethylmethoxy Chromanyl Palmitate, a clinically validated, non-cytotoxic molecule that effectively inhibits human tyrosinase\u2014the rate-limiting enzyme in melanogenesis. Unlike traditional agents like Hydroquinone, it exhibits no cellular toxicity and offers a significant photo-protective effect against UV-induced cellular damage, preventing premature photo-aging while correcting hyperpigmentation.<\/p>\n<h3><b>2. The Vector: Liposomal Transdermal Delivery<\/b><\/h3>\n<p>The human stratum corneum is a formidable barrier to hydrophobic molecules. Our advanced liposomes, composed of biocompatible phospholipids, mimic the skin\u2019s natural lipid bilayer.<\/p>\n<ul>\n<li><b>Enhanced Penetration:<\/b> The nanoscale vesicles effortlessly fuse with the cellular membranes of the epidermis, facilitating deep tissue penetration.<\/li>\n<li><b>Sustained Release:<\/b> The liposomal matrix provides a controlled, time-released effect, maintaining optimal active concentrations at the target site over an extended period.<\/li>\n<li><b>Superior Stability:<\/b> Encapsulation protects the active core from oxidation and formulation incompatibilities, ensuring maximum potency from the laboratory to the consumer.<\/li>\n<\/ul>\n<h2><b>Key Formulator Benefits &amp; Claims<\/b><\/h2>\n<ul>\n<li><b>Clean Beauty Compliant &amp; Self-Preserving:<\/b> Formulated entirely without conventional preservatives, this ingredient leverages an optimized, low-water-activity matrix for inherent microbiological stability. It perfectly aligns with strict &#8220;Clean Label&#8221; standards (e.g., Credo, Sephora Clean), reducing regulatory hurdles and formulation complexity for brand owners.<\/li>\n<li><b>Perfect Clear-System Compatibility:<\/b> Perfectly compatible with clear aqueous formulations. Its precise nanoscale dimensions evade Mie scattering, enabling the creation of completely transparent serums, high-performance toners, and ampoules without introducing turbidity.<\/li>\n<li><b>Exceptional Thermodynamic Stability:<\/b> Engineered for extreme resilience. <b>NanoActive&#x2122; DCP<\/b> withstands rigorous Freeze-Thaw Cycle Tests without demulsification, phase separation, or significant particle size growth, guaranteeing robust shelf-life and global supply chain reliability.<\/li>\n<li><b>Visible Brightening &amp; Tone Evening:<\/b> Significantly reduces the appearance of age spots, melasma, and post-inflammatory hyperpigmentation (PIH).<\/li>\n<li><b>Photo-Protection &amp; Anti-Aging:<\/b> Fights reactive oxygen species (ROS) and protects cells from UV-mediated damage.<\/li>\n<li><b>Unmatched Safety Profile:<\/b> Non-irritating, non-sensitizing, and free from the cytotoxic side effects associated with conventional lightening agents.<\/li>\n<li><b>Formulation Elegance:<\/b> Easy to incorporate into aqueous phases at the end of the manufacturing process (cold processable).<\/li>\n<\/ul>\n<h2><b>Cosmetic Applications<\/b><\/h2>\n<p>Ideal for premium dermatological and cosmetic formulations aimed at global skin tone improvement:<\/p>\n<ul>\n<li>Intensive Brightening Serums &amp; Essences<\/li>\n<li>Clear Aqueous Toners and Micellar Waters<\/li>\n<li>Anti-Dark Spot Targeted Treatments<\/li>\n<li>Daily Radiance Creams and Lotions<\/li>\n<li>Anti-Aging &amp; Photo-Protection Formulations<\/li>\n<\/ul>\n<h2><b>Formulation Guidelines<\/b><\/h2>\n<ul>\n<li><b>Incorporation:<\/b> Add to the cooling phase of emulsions (below 40\u00b0C) or directly into the aqueous phase of gels and serums under gentle stirring.<\/li>\n<li><b>pH Stability:<\/b> Optimal performance within a pH range of 4.5 to 7.0.<\/li>\n<li><b>Compatibility:<\/b> Compatible with most cosmetic ingredients; avoid high shear forces post-addition to maintain liposome integrity. Excellent suitability for clear or transparent formulations.<\/li>\n<\/ul>\n<p><i>Disclaimer: The information provided is for educational and B2B formulation purposes. Final product claims must be validated by the brand owner according to local cosmetic regulations.<\/i><\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-784a7abdf5a4ee03a4545155ca8b6a16~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1777716549-0-0-daed185c8ad599d017936a30137469bb&amp;bizSceneCode=article_draft&amp;expiration=1777716549&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"405\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-784a7abdf5a4ee03a4545155ca8b6a16~resize:0:q75.png?source=1f5c5e47&amp;expiration=1777720010&amp;auth_key=1777720010-0-0-24f09d23209a195fba938f2439591626&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2033970724419937846\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-dab2e47a3203f96cc5c28ce277dc3693~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1777720011&amp;auth_key=1777720011-0-0-786e4df44cc5ec1e7feb8c3501c2ef6e&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div><!-- .entry-content -->\n\t\t\n\t\t\n\t<\/div>\n\n<\/article><!-- #post-1236 -->\n\n\t\n\t\t\n<article id=\"post-1228\" class=\"post-1228 post type-post status-publish format-standard hentry category-news tag-anti-dandruff tag-anti-oxidation\">\n\n\t\n\t<div class=\"entry-main\">\n\n\t\t\n\t\t<header class=\"entry-header\">\n\t\t\t\n\t\t\t<h1 class=\"entry-title\"><a href=\"http:\/\/www.puriactives.com\/en\/?p=1228\" title=\"Permalink to NanoActive DMC\" rel=\"bookmark\">NanoActive DMC<\/a><\/h1>\n\n\t\t\t\t\t\t\t<div class=\"entry-meta\">\n\t\t\t\t\tPosted on <a href=\"http:\/\/www.puriactives.com\/en\/?p=1228\" title=\"00:41\" rel=\"bookmark\"><time class=\"entry-date\" datetime=\"2026-04-30T00:41:44+08:00\">04\/30\/2026<\/time><\/a><time class=\"updated\" datetime=\"2026-04-30T00:44:35+08:00\">04\/30\/2026<\/time> <span class=\"byline\"> by <span class=\"author vcard\"><a class=\"url fn n\" href=\"http:\/\/www.puriactives.com\/en\/?author=2\" title=\"View all posts by L, Y\" rel=\"author\">L, Y<\/a><\/span><\/span> \t\t\t\t<\/div><!-- .entry-meta -->\n\t\t\t\n\t\t<\/header><!-- .entry-header -->\n\n\t\t\t\t\t<div class=\"entry-content\">\n\t\t\t\t<h2>Advanced Delivery System by PuriPharm Co. Ltd.<\/h2>\n<p><b>Liposomal Dimethylmethoxy Chromanol. <\/b>The ultimate dual-scavenger shield against Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS), engineered for maximum bioavailability.<\/p>\n<h2>1. Redefining Antioxidant Protection<\/h2>\n<p>Dimethylmethoxy Chromanol is widely recognized as one of the most potent synthetic analogs of \u03b3-tocopherol. Unlike traditional antioxidants that only target Oxygen free radicals, DMC is a unique <b>dual-scavenger<\/b>, effectively neutralizing both ROS and RNS, preventing lipid peroxidation and protein damage.<\/p>\n<p>However, incorporating DMC into cosmetic formulations presents challenges due to its solubility and stability issues. <b>PuriPharm\u2019s NanoActive technology <\/b>solves this by encapsulating DMC within nanometric liposomal vesicles. This structural mimicry of the stratum corneum ensures superior stability, profound epidermal penetration, and sustained release of the active molecule.<\/p>\n<p>Key Advantages:<\/p>\n<ul>\n<li>Dual Scavenging: Neutralizes both ROS and RNS, offering 360\u00b0 cellular protection.<\/li>\n<li>Liposomal Delivery: Nano-scale vesicles ensure deep penetration and prolonged efficacy.<\/li>\n<li>Photo-aging Defense: Prevents UV-induced DNA damage and premature skin aging.<\/li>\n<li>Formulation Friendly: Water-soluble liposomes easily integrate into aqueous phases.<\/li>\n<\/ul>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img loading=\"lazy\" class=\"aligncenter size-full wp-image-1231\" src=\"http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72471-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1706\" srcset=\"http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72471-scaled.jpg 2560w, http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72471-300x200.jpg 300w, http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72471-1024x682.jpg 1024w, http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72471-768x512.jpg 768w, http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72471-1536x1024.jpg 1536w, http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72471-2048x1365.jpg 2048w, http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72471-272x182.jpg 272w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/><\/h1>\n<h2>2. The Science Behind the Shield<\/h2>\n<p>A targeted approach to cellular defense and delivery.<\/p>\n<h2>\u2460 ROS &amp; RNS Quenching<\/h2>\n<p>Environmental stressors (pollution, UV) trigger ROS (like Superoxide) and RNS (like Peroxynitrite). DMC acts as an electron donor, rapidly stabilizing these radicals before they can initiate cascading lipid peroxidation in cell membranes.<\/p>\n<h2>\u2461 Phospholipid Bilayer Integration<\/h2>\n<p>PuriPharm encapsulates DMC in a flexible, biocompatible phospholipid bilayer. This liposome protects the fragile DMC molecule from premature oxidation within the cosmetic formula, dramatically increasing shelf-life.<\/p>\n<h2>\u2462 Targeted Release<\/h2>\n<p>Due to their nanometric size (&lt; 100nm) and biomimetic nature, the liposomes fuse with the stratum corneum, releasing DMC directly into the deeper epidermal layers where cellular protection is most critical.<\/p>\n<h2>3. Technical Specifications<\/h2>\n<p>Designed for cosmetic formulators seeking uncompromising quality, stability, and ease of use in advanced skincare architectures.<img loading=\"lazy\" class=\"aligncenter size-full wp-image-1232\" src=\"http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72478.png\" alt=\"\" width=\"1280\" height=\"584\" srcset=\"http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72478.png 1280w, http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72478-300x137.png 300w, http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72478-1024x467.png 1024w, http:\/\/www.puriactives.com\/en\/wp-content\/uploads\/2026\/04\/\u56fe\u72478-768x350.png 768w\" sizes=\"(max-width: 1280px) 100vw, 1280px\" \/><\/p>\n<h2>4. Applications<\/h2>\n<ul>\n<li>Anti-Aging Serums: Prevent structural protein degradation.<\/li>\n<li>Anti-Pollution Creams: Shield against urban environmental stress.<\/li>\n<li>Suncare &amp; After-Sun: Mitigate UV-induced oxidative cascade.<\/li>\n<li>Brightening Essences: Prevent oxidation-triggered melanogenesis.<\/li>\n<\/ul>\n<p>\u00a9 2026 PuriPharm Co. Ltd. Leading the evolution of bio-delivery systems.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/picx.zhimg.com\/80\/v2-be930f7a1e7e4ef37248113a7f2ef6a8_720w.png\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"600\" data-rawheight=\"200\" data-watermark=\"original\" data-original-src=\"https:\/\/picx.zhimg.com\/v2-be930f7a1e7e4ef37248113a7f2ef6a8.png\" data-watermark-src=\"https:\/\/pic1.zhimg.com\/v2-a30253b6c29f722236dd4cb7bc7aa8ed.png\" data-private-watermark-src=\"\" \/><\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div><!-- .entry-content -->\n\t\t\n\t\t\n\t<\/div>\n\n<\/article><!-- #post-1228 -->\n\n\t\n\t\t\n<article id=\"post-1225\" class=\"post-1225 post type-post status-publish format-standard hentry category-news tag-nano-liposomal-haematococcus-astaxanthin-anti-oxidation tag-quaternary-ammonium-salt-73\">\n\n\t\n\t<div class=\"entry-main\">\n\n\t\t\n\t\t<header class=\"entry-header\">\n\t\t\t\n\t\t\t<h1 class=\"entry-title\"><a href=\"http:\/\/www.puriactives.com\/en\/?p=1225\" title=\"Permalink to LipoEcdysone&#x2122; PRO: The Biomimetic Phytosteroid Revolution\" rel=\"bookmark\">LipoEcdysone&#x2122; PRO: The Biomimetic Phytosteroid Revolution<\/a><\/h1>\n\n\t\t\t\t\t\t\t<div class=\"entry-meta\">\n\t\t\t\t\tPosted on <a href=\"http:\/\/www.puriactives.com\/en\/?p=1225\" title=\"23:24\" rel=\"bookmark\"><time class=\"entry-date\" datetime=\"2026-04-24T23:24:35+08:00\">04\/24\/2026<\/time><\/a><time class=\"updated\" datetime=\"2026-04-24T23:24:36+08:00\">04\/24\/2026<\/time> <span class=\"byline\"> by <span class=\"author vcard\"><a class=\"url fn n\" href=\"http:\/\/www.puriactives.com\/en\/?author=2\" title=\"View all posts by L, Y\" rel=\"author\">L, Y<\/a><\/span><\/span> \t\t\t\t<\/div><!-- .entry-meta -->\n\t\t\t\n\t\t<\/header><!-- .entry-header -->\n\n\t\t\t\t\t<div class=\"entry-content\">\n\t\t\t\t<h2>Advanced Liposomal Hydroxyecdysone for High-Performance Cosmetics &amp; Nutraceuticals<\/h2>\n<h2>1. Product Concept: Unlocking Nature&#8217;s Blueprint<\/h2>\n<p>Hydroxyecdysone (20-HE) is a highly potent phytosteroid naturally found in select adaptogenic plants. Renowned for its extraordinary ability to stimulate cellular vitality and protein synthesis, its traditional application has been limited by poor solubility and low bioavailability.<\/p>\n<p>Enter <b>LipoEcdysone&#x2122; PRO<\/b>. By utilizing cutting-edge, pharmaceutical-grade liposomal encapsulation technology, we have engineered a highly stable, bioavailable delivery system. Our biomimetic phospholipid vesicles seamlessly integrate with human cell membranes, ensuring deep tissue penetration and targeted active release\u2014bridging the gap between natural potential and ultimate clinical efficacy.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-ddcf52fb0fe7f37864930fc634971a71~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1777042689-0-0-464b3d995e6ede0c237ae9a8595dae99&amp;bizSceneCode=article_draft&amp;expiration=1777042689&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"900\" data-rawheight=\"1125\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-ddcf52fb0fe7f37864930fc634971a71~resize:0:q75.png?source=1f5c5e47&amp;expiration=1777045888&amp;auth_key=1777045888-0-0-906dbe4448b29f963913836ad69959e6&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2031132145595499491\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-22b0414924a7fb1dfe7915d7b375a33f~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1777045888&amp;auth_key=1777045888-0-0-96e1716df40d4d939a169524cf2be361&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\"><\/h1>\n<h2>2. The Liposomal Advantage: Science Meets Delivery<\/h2>\n<p>Standard Hydroxyecdysone struggles to cross the stratum corneum in skin or survive enzymatic degradation in the gut. Our proprietary liposomal matrix solves this:<\/p>\n<ul>\n<li><b>Biomimetic Penetration:<\/b> Phospholipid bilayers mimic cellular structures, facilitating endocytosis and direct intracellular delivery.<\/li>\n<li><b>Enhanced Stability: <\/b>Protects the active phytosteroid from oxidation, pH variations, and metabolic breakdown.<\/li>\n<li><b>Sustained Release: <\/b>Controlled time-release mechanism prevents active degradation and prolongs biological efficacy.<\/li>\n<\/ul>\n<h2>3. Cosmetic Applications (Personal Care)<\/h2>\n<h2>Architecting Skin Density &amp; Resilience from Within<\/h2>\n<p>In cosmetic formulations, LipoEcdysone&#x2122; PRO acts as a powerful anti-aging and skin-restoring agent. It stimulates the skin&#8217;s natural regenerative pathways without the side effects associated with synthetic retinoids.<\/p>\n<p><b>Key Mechanisms &amp; Benefits:<\/b><\/p>\n<ul>\n<li><b>Epidermal Reinforcement:<\/b> Accelerates keratinocyte differentiation, fortifying the skin barrier and increasing epidermal thickness.<\/li>\n<li><b>Dermal Matrix Redensification: <\/b>Up-regulates the synthesis of Collagen I and III, effectively improving skin elasticity and smoothing deep wrinkles.<\/li>\n<li><b>Micro-Wound Healing:<\/b> Ideal for post-procedure or compromised skin, promoting rapid tissue repair through enhanced cellular crosstalk.<\/li>\n<\/ul>\n<p>Recommended Applications: Anti-aging serums, skin-barrier repair creams, post-treatment recovery lotions, and firming body care.<\/p>\n<h2>4. Nutraceutical Applications (Functional Foods &amp; Supplements)<\/h2>\n<h2>The Ultimate Natural Anabolic &amp; Metabolic Adaptogen<\/h2>\n<p>For the sports nutrition and longevity markets, LipoEcdysone&#x2122; PRO delivers unparalleled systemic benefits. By significantly increasing oral bioavailability, lower dosages achieve superior physiological results.<\/p>\n<p><b>Key Mechanisms &amp; Benefits:<\/b><\/p>\n<ul>\n<li><b>Muscle Protein Synthesis (MPS): <\/b>Activates the PI3K\/Akt signaling pathway, promoting lean muscle mass accretion and accelerating recovery post-exercise.<\/li>\n<li><b>Metabolic Homeostasis:<\/b> Acts as a powerful adaptogen, supporting glucose metabolism and mitigating the physical markers of stress.<\/li>\n<li><b>Joint &amp; Cartilage Support:<\/b> Exhibits anti-inflammatory properties, preserving extracellular matrix integrity in joints for aging populations and athletes.<\/li>\n<\/ul>\n<p><b>Recommended Applications:<\/b> Sports recovery shots, longevity capsules, adaptogenic functional beverages, and joint-health gummies.<\/p>\n<h2>5. Technical Specifications &amp; Formulation Guidelines<\/h2>\n<ul>\n<li><b>INCI Name:<\/b> Phospholipids (and) PHYTOECDYSTEROIDS.<\/li>\n<li><b>Appearance: <\/b>Translucent to slightly opalescent fluid.<\/li>\n<li><b>Particle Size (D50):<\/b> &lt; 150 nm (Ensuring optimal cellular uptake).<\/li>\n<li><b>Solubility:<\/b> Dispersible in water; compatible with both hydrophilic and lipophilic systems.<\/li>\n<li><b>Recommended Use Level:<\/b> * Cosmetics: 1.0% \u2013 5.0% (Add during the cooling phase, below 40\u00b0C).<\/li>\n<\/ul>\n<p><b>Nutraceuticals:<\/b> Please refer to local regulatory guidelines for dietary supplement dosing.<\/p>\n<ul>\n<li><b>Preservative System:<\/b>Self-preserving \/ Preservative-free options available.<\/li>\n<li><b>Sustainability: <\/b>Ethically sourced botanical extracts, solvent-free liposomal extrusion process, 100% vegan and cruelty-free.<\/li>\n<\/ul>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-d50cbe730489d703b3da66ff0cfce846~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1777042689-0-0-3026594a65ec086c0b63bcb04e0448fc&amp;bizSceneCode=article_draft&amp;expiration=1777042689&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1080\" data-rawheight=\"720\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-d50cbe730489d703b3da66ff0cfce846~resize:0:q75.png?source=1f5c5e47&amp;expiration=1777045888&amp;auth_key=1777045888-0-0-80d82253f05a1f06ab9e149fbd016616&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2031132145595499491\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-f7ebb7c99be35dc44d08b4cce7fefb41~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1777045888&amp;auth_key=1777045888-0-0-49b2914b0443aa32c927056d2981d20c&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\"><\/h1>\n<p><i>Disclaimer: The information provided is for B2B educational purposes. Finished product claims must be evaluated by the respective legal and regulatory bodies of the target markets.<\/i><\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/picx.zhimg.com\/80\/v2-be930f7a1e7e4ef37248113a7f2ef6a8_720w.png\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"600\" data-rawheight=\"200\" data-watermark=\"original\" data-original-src=\"https:\/\/picx.zhimg.com\/v2-be930f7a1e7e4ef37248113a7f2ef6a8.png\" data-watermark-src=\"https:\/\/picx.zhimg.com\/v2-a30253b6c29f722236dd4cb7bc7aa8ed.png\" data-private-watermark-src=\"\"><\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div><!-- .entry-content -->\n\t\t\n\t\t\n\t<\/div>\n\n<\/article><!-- #post-1225 -->\n\n\t\n\t\t\n<article id=\"post-1218\" class=\"post-1218 post type-post status-publish format-standard hentry category-news tag-anti-free-radicals tag-luojia-health-forum tag-nano-liposomal-haematococcus-astaxanthin-anti-oxidation tag-resists-uva\">\n\n\t\n\t<div class=\"entry-main\">\n\n\t\t\n\t\t<header class=\"entry-header\">\n\t\t\t\n\t\t\t<h1 class=\"entry-title\"><a href=\"http:\/\/www.puriactives.com\/en\/?p=1218\" title=\"Permalink to NanoActive Sulfur PRODUCT DATA SHEET\" rel=\"bookmark\">NanoActive Sulfur PRODUCT DATA SHEET<\/a><\/h1>\n\n\t\t\t\t\t\t\t<div class=\"entry-meta\">\n\t\t\t\t\tPosted on <a href=\"http:\/\/www.puriactives.com\/en\/?p=1218\" title=\"10:42\" rel=\"bookmark\"><time class=\"entry-date\" datetime=\"2026-04-19T10:42:09+08:00\">04\/19\/2026<\/time><\/a><time class=\"updated\" datetime=\"2026-04-19T10:42:09+08:00\">04\/19\/2026<\/time> <span class=\"byline\"> by <span class=\"author vcard\"><a class=\"url fn n\" href=\"http:\/\/www.puriactives.com\/en\/?author=2\" title=\"View all posts by L, Y\" rel=\"author\">L, Y<\/a><\/span><\/span> \t\t\t\t<\/div><!-- .entry-meta -->\n\t\t\t\n\t\t<\/header><!-- .entry-header -->\n\n\t\t\t\t\t<div class=\"entry-content\">\n\t\t\t\t<h2>Advanced Nano-Encapsulated Bio-Derived Sulfur for Multi-Targeted Skin Solutions<\/h2>\n<p><b>Company: <\/b>PuriPharm Co. Ltd.<\/p>\n<p><b>Website: <\/b>www.PuriActives.com<\/p>\n<p><b>Contact: <\/b>Service@puripharm.com | Tel: 13167223168<\/p>\n<h2>1. PRODUCT OVERVIEW<\/h2>\n<p>Sulfur is a naturally occurring nonmetal with a long-standing dermatological history of effectively treating various skin disorders. However, traditional sulfur applications are severely limited by poor water solubility, large particle sizes (2\u20135 \u03bcm), low bioavailability, and formulation challenges.<\/p>\n<p><b>NanoActive Sulfur<\/b>, developed by PuriPharm Co. Ltd., is a cutting-edge active ingredient that utilizes a proprietary Nano-Delivery System (NDS). By stably encapsulating highly active bio-derived sulfur into sub-30 nm lipid-based nanocarriers, it completely resolves traditional solubility and aesthetic issues. The result is a highly bioavailable, transparent, and universally compatible active that regulates sebum, reduces inflammation, and offers potent antibacterial properties for acne and scalp care.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-dc3665a13e0cd447160df9cf29767168~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776566412-0-0-1a1de993f2f32574572c0787fd7d94db&amp;bizSceneCode=article_draft&amp;expiration=1776566412&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1688\" data-rawheight=\"1125\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-dc3665a13e0cd447160df9cf29767168~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776569696&amp;auth_key=1776569696-0-0-89f847beaa6317ac79c24fa0efaa1f24&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-7228b962a66056526696abeb48e6aa8e~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776569696&amp;auth_key=1776569696-0-0-9df82c417c3893a4f8afcbf687f874d2&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>2. COMPOSITION &amp; INCI INFORMATION<\/h2>\n<p>NanoActive Sulfur is formulated using a specialized biomimetic lipid matrix designed for optimal trans-epidermal delivery. It is strictly free from added preservatives and antioxidants.<\/p>\n<p>Composition Range Table:<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-46190b4927698ad6f04f4bbfea8a9e2e~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776566412-0-0-56bb99d1e00a72f1ff661da341dacbd0&amp;bizSceneCode=article_draft&amp;expiration=1776566412&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1269\" data-rawheight=\"430\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-46190b4927698ad6f04f4bbfea8a9e2e~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776569695&amp;auth_key=1776569695-0-0-152d81870efa968c5e5b7525bf8ea9fc&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-059f19a1b00e911a51c2568c3aebe0d2~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776569695&amp;auth_key=1776569695-0-0-b172ab6733eae4a64b626a2fb25f2490&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>3. TECHNICAL SPECIFICATIONS<\/h2>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-0034ee85301c3a74e42d7f450e7afb12~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776566413-0-0-5ff1cf93d9ab42519ce3ae48e36f7b0e&amp;bizSceneCode=article_draft&amp;expiration=1776566413&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1254\" data-rawheight=\"733\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-0034ee85301c3a74e42d7f450e7afb12~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776569695&amp;auth_key=1776569695-0-0-bf8b46c50f31fe60d69fa25548781dd0&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-5dc37935bffc9cea0bd86d14fd56c310~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776569695&amp;auth_key=1776569695-0-0-759d7a3ff5a622368dc6fba184a67f8a&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>4. TECHNOLOGY HIGHLIGHTS: THE NDS ADVANTAGE<\/h2>\n<ul>\n<li>Ultra-Fine Particle Size (&lt; 30 nm): Significantly increases the specific surface area and interaction with keratinocytes, ensuring superior skin penetration and biological activity compared to traditional 2-5 \u03bcm sulfur.<\/li>\n<li>Exceptional Formulation Flexibility: The unique hydrophilic-lipophilic structural modification allows NanoActive Sulfur to be seamlessly incorporated into lotions, creams, clear gels, and water-based formulas without precipitation.<\/li>\n<li>Aesthetic Superiority: Unlike traditional sulfur, which is chalky and difficult to suspend, NanoActive Sulfur maintains optical clarity (forming a transparent solution at typical usage levels), leaving no residue and enabling elegant cosmetic formulations.<\/li>\n<li>High Stability &amp; Bioavailability: The robust phospholipid-based nanocarrier prevents aggregation, protects the active payload, and ensures targeted delivery to the sebaceous glands and follicles.<\/li>\n<\/ul>\n<h2>5. KEY COSMETIC BENEFITS &amp; MECHANISM OF ACTION<\/h2>\n<h2>A. Comprehensive Sebum Regulation &amp; Keratolysis<\/h2>\n<p>Excessive sebum accumulation leads to enlarged pores, follicular blockage, and inflammation. NanoActive Sulfur effectively removes surface lipids, softens the epidermis, and dissolves keratin plugs.<\/p>\n<p>\u25cf<b>Mechanism:<\/b>At low concentrations, sulfur exerts a keratoplastic effect, promoting normal keratinization. At higher concentrations, it becomes keratolytic, reacting with cysteine to form cystine and hydrogen sulfide (), which safely disrupts excess keratin and clears clogged pores.<\/p>\n<h2>B. Targeted Antibacterial &amp; Antifungal Action<\/h2>\n<p>NanoActive Sulfur acts as a potent purifying agent and helps rebalance the skin microbiome.<\/p>\n<p>\u25cf<b>Mechanism: <\/b>Skin bacteria and keratinocytes convert sulfur into pentathionic acid (), a compound highly toxic to fungi and pathogenic bacteria. The keratolytic action further helps detach microorganisms from the stratum corneum.<\/p>\n<p>\u25cf<b>Microbiological Efficacy (In Vitro):<\/b><\/p>\n<p>\u25cbP. aeruginosa: MIC = 1.95 \u03bcg\/mL | MBC = 1000 \u03bcg\/mL<\/p>\n<p>\u25cbS. aureus: MIC = 125 \u03bcg\/mL<\/p>\n<p>\u25cbE. coli: MIC = 500 \u03bcg\/mL<\/p>\n<h2>C. Powerful Anti-Inflammatory &amp; Soothing Properties<\/h2>\n<p>Severe oxidative stress depletes intracellular Glutathione (GSH), triggering inflammatory cascades.<\/p>\n<p>\u25cf<b>Mechanism:<\/b>NanoActive Sulfur supports cellular antioxidant defenses by promoting GSH synthesis.<\/p>\n<p>\u25cf<b>Efficacy:<\/b>Exerts a strong, dose-dependent reduction in the expression of key pro-inflammatory cytokines. Clinical evaluations (ELISA) show that concentrations between 0.1% and 0.4% significantly downregulate the protein expression of<b>IL-1\u03b2<\/b>,<b>IL-6<\/b>, and <b>TNF-\u03b1<\/b>.<\/p>\n<h2>D. Clinically Proven Acne Treatment<\/h2>\n<p>Inin-vivoassessments, formulations containing NanoActive Sulfur demonstrated visible improvement in acne-prone skin profiles. A 60-day application of 0.2% active showed a significant reduction in inflammatory lesions and post-acne erythema, making it an ideal candidate for long-term acne management.<\/p>\n<h2>6. RECOMMENDED APPLICATIONS<\/h2>\n<p>NanoActive Sulfur is highly versatile and is recommended for the following cosmetic product categories:<\/p>\n<ul>\n<li>Acne &amp; Blemish Control: Spot treatments, anti-acne serums, and purifying toners.<\/li>\n<li>Sebum Control &amp; Pore Refining: Mattifying lotions, oil-control powders, and deep-cleansing masks.<\/li>\n<li>Brightening &amp; Spot-Fading: Post-inflammatory hyperpigmentation (PIH) correctors.<\/li>\n<li>Scalp Care: Anti-dandruff shampoos and scalp-soothing serums (seborrheic dermatitis support).<\/li>\n<li>Soothing &amp; Repair: Products targeting sensitized, inflamed, or compromised skin barriers.<\/li>\n<\/ul>\n<h2>7. FORMULATION GUIDANCE<\/h2>\n<ul>\n<li>Suggested Use Level: 0.1% \u2013 5.0% (Depending on target efficacy: low doses for daily maintenance\/anti-inflammation; higher doses for targeted spot treatments).<\/li>\n<li>Solubility: Amphiphilic nature allows it to be easily added to either the aqueous phase or the final emulsion at room temperature or gently heated conditions.<\/li>\n<li>Compatibility: Compatible with a wide range of cosmetic ingredients, including traditional water-based and oil-based systems. Does not cause phase separation.<\/li>\n<\/ul>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-3e4741e5ede7b7be67023f081d3d12e4~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776566413-0-0-aed4b2fe43cc5672e5f36fa5eec6c853&amp;bizSceneCode=article_draft&amp;expiration=1776566413&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"2000\" data-rawheight=\"1125\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-3e4741e5ede7b7be67023f081d3d12e4~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776569695&amp;auth_key=1776569695-0-0-9dcca4853f2f5853a4c5acf1df35fad2&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-3091af76d1e36f49beae706fa1c3b51c~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776569696&amp;auth_key=1776569696-0-0-68026dce6347fdf49994a59ea6b66b8c&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>8. STORAGE, HANDLING &amp; PACKAGING<\/h2>\n<ul>\n<li>Storage: Store in the original, unopened container at 4\u00b0C to 25\u00b0C. Protect from direct sunlight and maintain in a dry environment.<\/li>\n<li>Shelf Life: 12 months under specified storage conditions.<\/li>\n<li>Packaging: Supplied in standard industrial plastic containers.<\/li>\n<\/ul>\n<p>Disclaimer: The information contained in this document is provided in good faith and is based on our current knowledge and internal testing. Formulators are responsible for ensuring the final cosmetic product&#8217;s stability, safety, and regulatory compliance in their respective target markets.<\/p>\n<p>PuriPharm Co. Ltd. | Advanced Active Ingredients<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/picx.zhimg.com\/80\/v2-be930f7a1e7e4ef37248113a7f2ef6a8_720w.png\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"600\" data-rawheight=\"200\" data-watermark=\"original\" data-original-src=\"https:\/\/picx.zhimg.com\/v2-be930f7a1e7e4ef37248113a7f2ef6a8.png\" data-watermark-src=\"https:\/\/pic1.zhimg.com\/v2-a30253b6c29f722236dd4cb7bc7aa8ed.png\" data-private-watermark-src=\"\" \/><\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div><!-- .entry-content -->\n\t\t\n\t\t\n\t<\/div>\n\n<\/article><!-- #post-1218 -->\n\n\t\n\t\t\n<article id=\"post-1216\" class=\"post-1216 post type-post status-publish format-standard hentry category-news tag-anti-dandruff tag-anti-free-radicals tag-anti-oxidation\">\n\n\t\n\t<div class=\"entry-main\">\n\n\t\t\n\t\t<header class=\"entry-header\">\n\t\t\t\n\t\t\t<h1 class=\"entry-title\"><a href=\"http:\/\/www.puriactives.com\/en\/?p=1216\" title=\"Permalink to NanoActive Sulfur\" rel=\"bookmark\">NanoActive Sulfur<\/a><\/h1>\n\n\t\t\t\t\t\t\t<div class=\"entry-meta\">\n\t\t\t\t\tPosted on <a href=\"http:\/\/www.puriactives.com\/en\/?p=1216\" title=\"22:07\" rel=\"bookmark\"><time class=\"entry-date\" datetime=\"2026-04-18T22:07:36+08:00\">04\/18\/2026<\/time><\/a><time class=\"updated\" datetime=\"2026-04-18T22:07:36+08:00\">04\/18\/2026<\/time> <span class=\"byline\"> by <span class=\"author vcard\"><a class=\"url fn n\" href=\"http:\/\/www.puriactives.com\/en\/?author=2\" title=\"View all posts by L, Y\" rel=\"author\">L, Y<\/a><\/span><\/span> \t\t\t\t<\/div><!-- .entry-meta -->\n\t\t\t\n\t\t<\/header><!-- .entry-header -->\n\n\t\t\t\t\t<div class=\"entry-content\">\n\t\t\t\t<h2>Introduction<\/h2>\n<p>Sulfur is a yellow nonmetal widely distributed throughout the earth and has long been used as an effective treatment for various skin disorders. Its activity depends on the interaction between sulfur particles and keratinocytes: the smaller the particles, the larger the contact area and the better the efficacy. Bio-derived sulfur formed by the bacterial oxidation of sulfides into elemental sulfur shows better spreadability on the skin and higher activity.<\/p>\n<p>NanoActive Sulfur, developed through a nano-delivery system, effectively regulates sebum secretion and helps treat acne and dandruff, while also providing strong antibacterial and anti-inflammatory activity.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-7d8cd2a1b77b359e5666edfaa418a88f~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-d57383eab9e52255dd0627421fba5a8f&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"423\" data-rawheight=\"303\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-7d8cd2a1b77b359e5666edfaa418a88f~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-f8db9e47571cbc95a488c35b1b0527e8&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-647b2ac199eb07c78efae9e533893327~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-b023697ada4165f4e1a2a325678d3610&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Sebum Regulation<\/h2>\n<p>Excessive sebum secretion accumulates in follicles, enlarges pores, causes follicular blockage, and may even trigger inflammation.<\/p>\n<p>NanoActive Sulfur effectively removes excess surface oil and helps soften the epidermis. It can also dissolve keratin and relieve skin imbalance caused by overactive oil secretion. In addition, it helps improve acne, pimples, and seborrheic dermatitis associated with overactive sebaceous glands.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-c5be0541eb27074a9f72156596847089~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-fb5356ca9c447f6cbc2a2313c30d1db7&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"618\" data-rawheight=\"630\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-c5be0541eb27074a9f72156596847089~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524677&amp;auth_key=1776524677-0-0-83d16c22608a051d0ae20000ecfa8d09&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-9d35ee308e63e42d7ac08c3fd9932ca6~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524678&amp;auth_key=1776524678-0-0-3d56e1184371a3ef6fb6905c7ecbe688&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Keratolytic Effect<\/h2>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-fcf2137ded630b93df976e22b2c61c17~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-9b82610987be942ff15afa7e6191ead0&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1475\" data-rawheight=\"124\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-fcf2137ded630b93df976e22b2c61c17~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-d0d7fbdaa1f43b3bfddd6ccb1876be00&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-fcf2137ded630b93df976e22b2c61c17~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-77619324732b1947a8027ff9aa8d0654&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<p>Cystine is a major component of the stratum corneum. At low concentrations, sulfur promotes normal keratinization through its keratoplastic activity. At high concentrations, the same reaction produces a keratolytic effect because hydrogen sulfide disrupts keratin, and sufficient accumulation can dissolve the stratum corneum.<\/p>\n<p>Therefore, NanoActive Sulfur is recommended for cosmetic formulations designed to regulate sebum secretion.<\/p>\n<h2>Antibacterial Action<\/h2>\n<p>The antibacterial action of sulfur depends on its conversion into pentathionic acid (H\u2082S\u2085O\u2086), a compound toxic to fungi. Hydrogen sulfide may also contribute to this activity. Through the action of skin bacteria and keratin-forming cells, sulfur can be converted into pentathionic acid. In addition, sulfur&#8217;s keratolytic activity may help separate fungi from the stratum corneum.<\/p>\n<p>Therefore, NanoActive Sulfur is recommended for cosmetic formulations with purifying and preservative functions.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-9af42d075ed2c8c67db6948545e2e4f7~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-13c3e0e542d94a65d70dfb4ade54d9f9&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"444\" data-rawheight=\"444\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-9af42d075ed2c8c67db6948545e2e4f7~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-d49fab6934d3a3e308799d2bc203ba0c&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-175df6a32203f087adca0dad8cc96fb4~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-f29e96bdb7c62a6fa0aec58ff484509e&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Pentathionic Acid Activity<\/h2>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-c45b50579904972d40af15d8db6bbfdf~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-978bfa01713ce73f35210e67d2e7dd00&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1493\" data-rawheight=\"479\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-c45b50579904972d40af15d8db6bbfdf~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-bf7e6d9235dc9a9fb1ed2374307d90b5&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-8397f380fe95e53a5713b15998e77c46~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-5bccb1a4d4e20c158e2a5cd2e84c3280&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Anti-inflammatory Action<\/h2>\n<p>Glutathione (GSH) is the most important cellular antioxidant. It exists in the reduced thiol form (GSH) and the oxidized disulfide form (GSSG), and undergoes thiol-disulfide exchange catalyzed by thiol transferases. Severe oxidative stress depletes intracellular GSH.<\/p>\n<p>NanoActive Sulfur can promote GSH synthesis while reducing pro-inflammatory cytokines such as IL-1, IL-6, and TNF-\u03b1, delivering a strong anti-inflammatory effect.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-e3d34ebc7def7753d3b1ed9d5c9204f4~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-18af811fe9f6cea80ce4372a96721912&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"582\" data-rawheight=\"346\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-e3d34ebc7def7753d3b1ed9d5c9204f4~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-6977eecfc3790badb94d673bf1ce69e5&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-728e821a185d394b7f64bceec467ac5f~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-82b6d864f7ae9350e4ffd17cc4a2bba8&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Inflammatory Factor Reduction<\/h2>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-49e561611d2f022220c0d9edc3e2475e~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-9023b22e7f8ee16b5dfa8b7cab1d01e5&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1051\" data-rawheight=\"759\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-49e561611d2f022220c0d9edc3e2475e~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-d6e8fcf75bda3406bf76deff570eec16&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-b70f8e949439dfdd992951ba7b0fd72e~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-0503eb71ee9f68b88c03cc5825a8ed28&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><img src=\"https:\/\/pic-out.zhimg.com\/v2-0ad691aa17c2e1f7d4e8f13dd9119de2~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-ea2d3814c328e5832c664bb5ddbccf07&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"878\" data-rawheight=\"556\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-0ad691aa17c2e1f7d4e8f13dd9119de2~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-363f742d35806f3a9cae5ee3d5bf6f58&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-83ea5499d156fa4a44b0307fb8d66114~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524563&amp;auth_key=1776524563-0-0-62d2571688b0f642cdaf6a771c065e9a&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Inflammatory Factor Reduction<\/h2>\n<p>The protein expression levels of TNF-\u03b1, IL-1\u03b2, and IL-6 were measured by ELISA.<\/p>\n<p>Compared with the control group, NanoActive Sulfur reduced the expression of TNF-\u03b1, IL-1\u03b2, and IL-6 in a dose-dependent manner.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-86af996b7f323e2de4a46b919530ec7b~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-7f091640e942d20ca35a694c2a423648&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"787\" data-rawheight=\"498\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-86af996b7f323e2de4a46b919530ec7b~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-3b22e859bfaa4b004a58a0788f2489df&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-1e597a0ed9d866f1766e8246de474840~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-25b9e9ff488836b7539588d679783edd&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>NanoActive Sulfur in Acne Treatment<\/h2>\n<p>5% NanoActive Sulfur 2 months<\/p>\n<p>Visible improvement in acne appearance after continuous use.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-3f5314b27df83c7ef0b5adfe0c0efb16~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-75092b64620b10cf095dc88bdbcdd5ab&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"773\" data-rawheight=\"495\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-3f5314b27df83c7ef0b5adfe0c0efb16~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-4b294707e48a828be8832891b2df9732&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-9209545e1e2612a5183e1dd8d337f2fd~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-99920ff07806375b6bd704f0fadaf35f&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Challenges in Sulfur Applications<\/h2>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-ccddcf49bad634c251a5864ee8334d59~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-0878dddb0ee59d5c73a864021968b207&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"2142\" data-rawheight=\"916\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-ccddcf49bad634c251a5864ee8334d59~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-c73bbf0666d3ef35029ded2b62240ba2&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-23623687c61f16af8ec05853694ebb36~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-8f28ab324a0582f782eb0521afcf5577&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Advantages of NanoActive Sulfur<\/h2>\n<p>NanoActive Sulfur has a unique chemical structure (linear and hydrophilic), making it easier to formulate, easier to combine with other ingredients, and easier to absorb.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-af889fd9a076d80f84a3baa06e29ccbc~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-e5e0834492679329277f12c1a737bbbe&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1412\" data-rawheight=\"699\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-af889fd9a076d80f84a3baa06e29ccbc~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-d589eb8f0d6cfe28f731bb0597d8f4c8&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-87c4edaf868b1064192c6568c80c9638~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-a1e2967f7e998edc248fcae92bbf7159&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Nano-delivery System<\/h2>\n<p>NanoActive Sulfur developed with a nano-delivery system (NDS) has a particle size below 30 nm. It completely solves sulfur solubility issues by stably encapsulating sulfur inside nano-carriers, greatly improving absorption efficiency and bioavailability.<\/p>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-b4db13b28962655ee883cad05ab19c28~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-3bb23d3a09b3ffcb63d13a8e17fe2e21&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1073\" data-rawheight=\"162\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-b4db13b28962655ee883cad05ab19c28~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-36cf063e3017ead7b4c36e68e0c3f0fe&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-b4db13b28962655ee883cad05ab19c28~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-d5b6364b5fffb6d05940ff047bc5e7a6&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>NanoActive Sulfur<\/h2>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img src=\"https:\/\/pic-out.zhimg.com\/v2-5dc98e982d99f4c5cc4fc8f7c18061db~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-6f0c17a5bff9828b0c1c39f458122d6f&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"2329\" data-rawheight=\"488\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-5dc98e982d99f4c5cc4fc8f7c18061db~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-72c79283700e00c0a36ee443db65a70a&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-d087c5a6249912b2b856977023735fc3~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-31b441900e66d6e88503fe65ef1d5d5a&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Applications<\/h2>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img loading=\"lazy\" class=\"\" src=\"https:\/\/pic-out.zhimg.com\/v2-10fd28e75e6c3a5c843454fc33909b4b~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-91743a538bc3a429d202e80fe40405d5&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" width=\"1146\" height=\"691\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1590\" data-rawheight=\"958\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-10fd28e75e6c3a5c843454fc33909b4b~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524563&amp;auth_key=1776524563-0-0-5754e8e7c4cb2a3118a6cf10f0cd45d5&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-047666804ef16c10d207105a1d1ced7d~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524563&amp;auth_key=1776524563-0-0-c623ea12cc12f4757d9ead14b6a214c4&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/h1>\n<h2>Market Cases<\/h2>\n<h1 data-layout-id=\"0\" data-pm-slice=\"0 0 []\"><img loading=\"lazy\" class=\"\" src=\"https:\/\/pic-out.zhimg.com\/v2-c90357a29b363cd0facacafd0e488d1c~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1776521291-0-0-fc19d13ec8814fa20697d8a332d98921&amp;bizSceneCode=article_draft&amp;expiration=1776521291&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" width=\"902\" height=\"253\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"1770\" data-rawheight=\"496\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-c90357a29b363cd0facacafd0e488d1c~resize:0:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-e8d284ff7e7002d18915f4121382a6e6&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2028956597313881636\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-50f9c8c5e49fef1a1ee7fba51e7f6daa~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1776524562&amp;auth_key=1776524562-0-0-6115e0a21eed739a350af7bf934daab5&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><img src=\"https:\/\/picx.zhimg.com\/80\/v2-be930f7a1e7e4ef37248113a7f2ef6a8_720w.png\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"600\" data-rawheight=\"200\" data-watermark=\"original\" data-original-src=\"https:\/\/picx.zhimg.com\/v2-be930f7a1e7e4ef37248113a7f2ef6a8.png\" data-watermark-src=\"https:\/\/picx.zhimg.com\/v2-a30253b6c29f722236dd4cb7bc7aa8ed.png\" data-private-watermark-src=\"\" \/><\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div><!-- .entry-content -->\n\t\t\n\t\t\n\t<\/div>\n\n<\/article><!-- #post-1216 -->\n\n\t\n\t\t<nav id=\"nav-below\" class=\"site-navigation paging-navigation\">\n\t\t<h2 class=\"assistive-text\">Post navigation<\/h2>\n\n\t\n\t\t<div class='pagination'><span aria-current=\"page\" class=\"page-numbers current\">1<\/span>\n<a class=\"page-numbers\" href=\"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fpages%2F857&#038;paged=2\">2<\/a>\n<a class=\"page-numbers\" href=\"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fpages%2F857&#038;paged=3\">3<\/a>\n<a class=\"page-numbers\" 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-->\n\t\n<\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/pages\/857"}],"collection":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=857"}],"version-history":[{"count":4,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/pages\/857\/revisions"}],"predecessor-version":[{"id":860,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/pages\/857\/revisions\/860"}],"wp:attachment":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=857"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}