![](\"https:\/\/pic-out.zhimg.com\/v2-1ce3c6af1adcd9a708efe9940aa084bf~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-deb7e337780ec11eb906f87a4848480a&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\nPURIPHARM CO. LTD. & PURIACTIVES\u00ae PLATFORM<\/p>\n
PuriPharm Co. Ltd. is a leading supplier of high-purity functional cosmetic actives, specializing in nano-encapsulation and advanced delivery systems for the global beauty industry.<\/p>\n
The PuriActives\u00ae platform represents a portfolio of science-backed, formulation-friendly active ingredients designed for modern skin and scalp care formulations.<\/p>\n
<\/p>\n
Each ingredient in the PuriActives\u00ae portfolio is selected and optimized for:<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-0dc0db6c35be04e1e54f86cc32508d47~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-055a6b89127c1b82172294f622117a37&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
![](\"https:\/\/pic-out.zhimg.com\/v2-f578e1c7b59b46e96f9f2408ece9943a~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-5a5e9ba986a109ab4f8509cabfd3334d&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Azelaic acid is a well-recognized cosmetic ingredient with multiple skin benefits. However, its practical use in cosmetic formulations has been limited by poor water solubility, low pH requirements, and skin tolerability concerns.<\/p>\n
Potassium azeloyl diglycinate (PAD) was developed as a water-soluble derivative that retains the beneficial properties of azelaic acid while overcoming its formulation limitations.<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-de68c2801c647cd33af53d6af6acdad1~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-41833eeeae4fc4f5d63d8da2026ca356&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Side-by-side comparison of key properties<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-f1ba0c6bd4ef167c8c3b789f61b63efe~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-6d8687eadd60654a81fd134c961fcb49&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-3184d0f35ef4980f4175b166ce559dfc~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-d51877f7e24f507026135847ffd60036&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Oily, Blemish-Prone, Uneven-Tone & Sensitive Skin<\/p>\n
Global consumers increasingly seek multifunctional, gentle solutions for complex skin concerns. PuriActives\u00ae PAD addresses all of these needs in a single molecule.<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-146c0ca423802e5235eada2938e4f361~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-2b1836f987bf04c687562ec0728e6f5d&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
PuriActives\u00ae PAD works through five complementary pathways for comprehensive skin, scalp, and hair benefits:<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-2909aa2bd5ecd1541d26f3556843fab9~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-a67ab15aaf2c6b02fdf60a0f382b2d6d&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Brightening Mechanism: Tyrosinase \/ Melanin Pathway<\/p>\n
Tyrosinase \u2014 The Rate-Limiting Enzyme<\/p>\n
Tyrosinase catalyzes the conversion of tyrosine to melanin pigments in melanocytes. It is the key regulatory enzyme in melanin synthesis, making it a primary target for skin-brightening actives.<\/p>\n
PAD Mechanism of Action<\/p>\n
PuriActives\u00ae PAD has been reported to inhibit tyrosinase activity, helping to reduce melanin production and supporting a brighter, more even-looking skin tone.<\/p>\n
Key Pathway Cascade<\/p>\n
PAD \u2192 Tyrosinase Inhibition \u2192 Reduced Melanin Synthesis \u2192 Brighter Skin Appearance<\/p>\n
Clinical Relevance<\/p>\n
Tyrosinase inhibitors are widely used in cosmetic brightening products. PAD offers a water-soluble, well-tolerated alternative for formulators seeking brightening efficacy without the formulation challenges of azelaic acid.<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-930b03a356ac1141c026005e9c1c704b~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-98928f603f073ca344ba56d14a535917&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Uneven Tone and Dark Spot Care<\/p>\n
Dark spots and uneven skin tone result from localized melanin overproduction, often triggered by UV exposure, hormonal changes, or post-inflammatory responses. PuriActives\u00ae PAD helps address this through its tyrosinase-inhibition-related activity, supporting a more uniform-looking complexion over continued use.<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-0c769aa5c5019371e63db637932b1105~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-7b75760e069da5f6a72308b1ea7d4f69&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Sebum Balance Mechanism<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-448be5ec9b6363199a4726049151a94e~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-625b192f0504709da55665ed2d71268e&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Blemish-Prone Skin Care Positioning<\/p>\n
Excess sebum, inflammation, and blemish formation are interconnected concerns. PuriActives\u00ae PAD’s dual action \u2014 sebum balance support plus anti-inflammatory properties \u2014 makes it well-suited for blemish-prone skin care formulations.<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-e4bd83da4ac3aad5d39e6be19dff20f1~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-941caeb63086dd12ae3bca374dde46fe&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Redness-Prone and Sensitive-Skin Comfort<\/p>\n
Redness-prone skin is often associated with elevated inflammatory mediators, including IL-1\u03b1 (interleukin-1 alpha), a key pro-inflammatory cytokine. PuriActives\u00ae PAD has been reported to help reduce IL-1\u03b1 release, providing anti-inflammatory support that soothes the appearance of redness. Combined with glycine’s skin-conditioning properties and a neutral pH of 6.5\u20137.5, PAD offers excellent tolerance for sensitive skin.<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-fbd951b1cdbf122464d8e8e79bb5ea25~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-279b1a8934c301e943fe4cf45e3ebbfc&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Hydration and Elasticity Support<\/p>\n
The glycine moiety in PuriActives\u00ae PAD contributes humectant and skin-conditioning properties. Glycine is a naturally occurring amino acid that helps support skin moisture retention, elasticity, and suppleness \u2014 complementing brightening and sebum-balancing benefits to create a well-rounded multifunctional active.<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-ac8bda966870ddc41c599061da8f6ca6~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-330195564f36e1db8de08b658167e7a3&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Scalp Care Opportunity<\/p>\n
Scalp health is increasingly recognized as the foundation of healthy-looking hair. Oily scalp, discomfort, and imbalance are common concerns. PuriActives\u00ae PAD’s sebum-regulating and anti-inflammatory properties translate effectively to scalp care, offering brands a science-backed active for this emerging category.<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-e10b39f3a8cc82b44e7b984428588420~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-17c863a79590668c7ad651fc2720c43b&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Hair-Care Mechanism: 5\u03b1-Reductase \/ IL-1\u03b1 \/ Scalp Balance<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-d24b66efd8cbcc4f2f2b713ebba75232~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-c36a6b50fca27b45f9a11b7961e68c2d&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
Hair Fiber Care Patent Story<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-9b080e8e562ce4884f3f14d5a165bcac~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-a724a17d6598ac49441d2fa9fcfc9167&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-e322a1f051e4fe86464286d38675370b~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-2b6fc713c2f7c5549b8db6c9abcbbdc2&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-45a8610ea3f740c2760af1c7645a01f3~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-11fab7953132aae067f46d7905275ab2&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-9204050279c61be8c0b09c8e582b5f3a~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-9f567e0bd5f63545c37248ad90f84cbf&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-009a3a334206e0a1c3c0614f1f8ca9ea~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-ba226c472c123c879ac3390f317f9ba5&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-7b56e7dcc898a847e65e13f1a45413d2~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-4796d33e1c076a8bc1925965591bc81b&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n
![](\"https:\/\/pic-out.zhimg.com\/v2-a96244b48a94c413ed7ec5a034aedda6~resize:1440:q75.png?animatedImageAutoPlay=false&animatedImagePlayCount=1&auth_key=1782212091-0-0-42ca44ba6f177f645006c068473ece60&bizSceneCode=article_draft&expiration=1782212091&incremental=false&mid=af87d0ba5943ed43c9d129c257d04f1b&overTime=60&precoder=false&protocol=v2&retryCount=3&sampling=false&sceneCode=editor_copy_outbound&source=bfcaadb1\")
<\/p>\n","protected":false},"excerpt":{"rendered":"
PURIPHARM CO. LTD. & PURIACTIVES\u00ae PLATFORM PuriPhar […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[25],"tags":[],"_links":{"self":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/posts\/1292"}],"collection":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1292"}],"version-history":[{"count":1,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/posts\/1292\/revisions"}],"predecessor-version":[{"id":1293,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/posts\/1292\/revisions\/1293"}],"wp:attachment":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1292"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1292"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1292"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}