{"id":1373,"date":"2026-08-29T12:20:39","date_gmt":"2026-08-29T04:20:39","guid":{"rendered":"http:\/\/www.puriactives.com\/en\/?p=1373"},"modified":"2026-08-29T12:20:39","modified_gmt":"2026-08-29T04:20:39","slug":"nanoactive-galabiome%e7%ba%b3%e7%b1%b3%e8%84%82%e8%b4%a8%e4%bd%93%e7%9b%8a%e7%94%9f%e5%85%83-%c2%b7-%e5%be%ae%e7%94%9f%e6%80%81%e5%b1%8f%e9%9a%9c%e5%8d%8f%e5%90%8c%e5%b9%b3%e5%8f%b0","status":"publish","type":"post","link":"http:\/\/www.puriactives.com\/en\/?p=1373","title":{"rendered":"NanoActive™ GalaBiome™\u7eb3\u7c73\u8102\u8d28\u4f53\u76ca\u751f\u5143 \u00b7 \u5fae\u751f\u6001\u5c4f\u969c\u534f\u540c\u5e73\u53f0"},"content":{"rendered":"

P U R I P H A R M\u00a0\u00a0 C O . ,\u00a0\u00a0 L T D .<\/strong><\/p>\n

PURIACTIVES\u00ae \u00b7 NANOACTIVE™ Nanoliposome Series<\/strong><\/p>\n

NanoActive™ GalaBiome™<\/strong><\/p>\n

Nanoliposomal Prebiotic Barrier Platform<\/p>\n

Microbiome \u00d7 Hydration \u00d7 Barrier<\/p>\n

PuriPharm Co. Ltd.<\/p>\n

 <\/p>\n

PARADIGM SHIFT<\/strong><\/p>\n

Moisturization Is More Than Adding Water<\/strong><\/p>\n

Skin hydration is an ecosystem function.<\/p>\n

Traditional moisturization focuses on humectants, occlusives, and emollients. Modern skin science shows that skin hydration is an ecosystem function created by multiple interacting factors.<\/p>\n

SIX KEY FACTORS<\/strong><\/p>\n

Lipid architecture; natural moisturizing factor (NMF); tight junctions; water transport; the acid mantle; and the skin microbiome.<\/p>\n

A MUTUALLY SUPPORTIVE LOOP<\/strong><\/p>\n

Healthy microbiome ↕ healthy barrier ↕ healthy hydration<\/p>\n

The three dimensions reinforce one another. An imbalance in any one dimension can propagate through the whole system\u2014this is the scientific basis of \u201cecosystem hydration.\u201d<\/p>\n

Reference: Lee HJ, Kim M. Skin Barrier Function and the Microbiome. Int J Mol Sci. 2022;23:13071. doi:10.3390\/ijms232113071.<\/p>\n

NanoActive™ GalaBiome™ \u00b7 PuriPharm Co. Ltd.<\/p>\n

 <\/p>\n

MICROBIOME \u00d7 BARRIER<\/strong><\/p>\n

Microbiome & Barrier: A Bidirectional Symbiotic Defense Network<\/strong><\/p>\n

DEFENSE PATHWAY<\/strong><\/p>\n

Microbial barrier \u2192 acid mantle \u2192 metabolites\/innate signals \u2192 keratinocyte differentiation \u2192 tight junctions \u2192 ceramide lipid barrier<\/p>\n

TEWL \u2193 \u00b7 HYDRATION \u2191<\/strong><\/p>\n

Lower transepidermal water loss and improved skin hydration<\/p>\n

Healthy commensal microorganisms help build four layers of defense:<\/p>\n

PHYSICAL<\/strong><\/p>\n

Commensals occupy ecological niches and reinforce the integrity of surface defenses.<\/p>\n

CHEMICAL<\/strong><\/p>\n

Metabolism produces organic acids that help maintain the acid mantle.<\/p>\n

MICROBIAL<\/strong><\/p>\n

Competition for nutrients and adhesion sites limits the dominance of opportunistic microbes.<\/p>\n

IMMUNE<\/strong><\/p>\n

Contributes to homeostatic regulation of innate and adaptive immune signaling.<\/p>\n

Healthy commensals do more than simply exist on the skin surface; they actively participate in the skin\u2019s defense network.<\/p>\n

Reference: Lee HJ, Kim M. Skin Barrier Function and the Microbiome. Int J Mol Sci. 2022;23:13071. doi:10.3390\/ijms232113071.<\/p>\n

NanoActive™ GalaBiome™ \u00b7 PuriPharm Co. Ltd.<\/p>\n

 <\/p>\n

PRODUCT OVERVIEW<\/strong><\/p>\n

One Platform. Four Biological Dimensions.<\/strong><\/p>\n

SELECTIVE PREBIOTIC POLYOL<\/strong><\/p>\n

Lactitol: a lactose-derived disaccharide polyol that supports a healthy skin microbiome through selective prebiotic logic\u2014selective nourishment rather than broad-spectrum feeding.<\/p>\n

HYDRATION & BARRIER BIOLOGY<\/strong><\/p>\n

XAX ternary sugar-derivative system: Xylitylglucoside + Anhydroxylitol + Xylitol\u2014multi-pathway hydration biology spanning water reserves, water circulation, and barrier lipids.<\/p>\n

BIOMIMETIC LIPID INTERFACE<\/strong><\/p>\n

Phospholipids: amphiphilic structures analogous to biological membranes, creating a biomimetic lipid interface while supporting barrier lipids.<\/p>\n

ADVANCED DELIVERY ARCHITECTURE<\/strong><\/p>\n

NanoActive™ nanoliposomes: nanoscale phospholipid vesicles encapsulate the aqueous phase of sugar-based actives for uniform distribution, local retention, and synergistic delivery.<\/p>\n

Biome \u00d7 hydration \u00d7 barrier \u00d7 delivery\u2014one platform, four biological dimensions.<\/p>\n

NanoActive™ GalaBiome™ \u00b7 PuriPharm Co. Ltd.<\/p>\n

 <\/p>\n

LACTITOL<\/strong><\/p>\n

Lactitol | Selective Prebiotic Logic from Sugar Science<\/strong><\/p>\n

IDENTITY<\/strong><\/p>\n

Lactitol is a lactose-derived disaccharide polyol. Its value is not limited to humectancy; it lies in the prebiotic potential created by selective fermentation.<\/p>\n

Feed the beneficial ecosystem, rather than simply feeding everything.<\/p>\n

SCIENTIFIC EVIDENCE<\/strong><\/p>\n

Pure-culture screening compared how broadly different candidate prebiotic substrates were used by microorganisms:<\/p>\n