{"id":1411,"date":"2026-09-27T13:56:01","date_gmt":"2026-09-27T05:56:01","guid":{"rendered":"http:\/\/www.puriactives.com\/en\/?p=1411"},"modified":"2026-09-27T13:56:01","modified_gmt":"2026-09-27T05:56:01","slug":"puriactives-sh50","status":"publish","type":"post","link":"http:\/\/www.puriactives.com\/en\/?p=1411","title":{"rendered":"PuriActives\u00ae SH50"},"content":{"rendered":"

PuriActives\u00ae SH50 Saccharide Hydrolysate<\/h2>\n

Advanced Sugar Science for Skin & Hair Hydration<\/p>\n

INCI \u2014 SACCHARIDE HYDROLYSATE \u00b7 CAS 8013-17-0<\/p>\n

A science-driven report for formulators, R&D scientists, and technical marketing teams<\/p>\n

01 \u00b7 MARKET OPPORTUNITY \u00b7 \u5e02\u573a\u673a\u9047<\/p>\n

Hydration: An Inevitable Imperative<\/h2>\n

Healthy skin and hair are, first and foremost, water-rich systems.<\/p>\n

In skin, stratum corneum water content determines flexibility, smoothness, and barrier performance \u2014 a healthy surface holds about 20\u201330% water, maintained by the skin’s own hygroscopic reservoir, the Natural Moisturizing Factor (NMF). In hair, water content governs flexibility, softness, and resistance to breakage. Yet daily life works against it: low humidity, cleansing, and aging continually erode the body’s own water-holding capacity.<\/p>\n

Consumer Demand<\/h3>\n

Soft, dewy, comfortable skin and smooth, manageable hair \u2014 every single day.<\/p>\n

The Biological Challenge<\/h3>\n

NMF depletion, accelerated water loss, and dry, fragile fibers.<\/p>\n

The Sugar Answer<\/h3>\n

Hydroxyl-rich molecules that capture, bind, and retain water exactly where skin and hair need it most.<\/p>\n

Three Drivers of Water Loss<\/h3>\n

\u2014 Low humidity, wind, and climate stress accelerate surface water loss<\/p>\n

\u2014 Surfactant cleansing washes away water-soluble NMF<\/p>\n

\u2014 Aging reduces the skin’s own production of NMF components<\/p>\n

Sources \u2014 Rawlings & Harding, Dermatol. Ther., 2004 \u00b7 Fowler, Pract. Dermatol., 2012<\/p>\n

02 \u00b7 PRODUCT IDENTITY \u00b7 \u4ea7\u54c1\u8eab\u4efd<\/p>\n

Meet PuriActives\u00ae SH50<\/h2>\n

Saccharide Hydrolysate\uff08\u7cd6\u7c7b\u6c34\u89e3\u7269\uff09<\/p>\n\n\n\n\n\n\n\n\n
INCI name<\/td>\nSaccharide Hydrolysate<\/td>\n<\/tr>\n
Identifiers<\/td>\nCAS 8013-17-0 \u00b7 EC 232-393-1<\/td>\n<\/tr>\n
Chemical nature<\/td>\nA plant-derived mixture of low-molecular-weight sugars<\/td>\n<\/tr>\n
Origin<\/td>\nProduced by directed hydrolysis (inversion) of food-grade natural sugars<\/td>\n<\/tr>\n
INCI functions<\/td>\nHumectant \u00b7 skin conditioning \u00b7 skin protecting<\/td>\n<\/tr>\n
Safety status<\/td>\nCIR Expert Panel \u2014 safe as used \u00b7 US FDA GRAS direct food additive \u00b7 Listed in China’s IECIC inventory<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/p>\n

Not an ordinary sugar blend \u2014 a well-defined, low-molecular-weight saccharide hydrolysate, built for modern water-based formulations.<\/p>\n

Sources \u2014 CIR safety assessment, Int. J. Toxicol., 2025 \u00b7 PubChem, Saccharide Hydrolysate (CAS 8013-17-0) \u00b7 IECIC 2021 \u00b7 PuriPharm process documentation<\/p>\n

03 \u00b7 SKIN BIOLOGY \u00b7 \u76ae\u80a4\u751f\u7269\u5b66<\/p>\n

Why Sugars Matter to Skin<\/h2>\n

NMF accounts for 20\u201330% of stratum corneum dry weight \u2014 and sugars themselves are natural NMF components.<\/p>\n

<\/p>\n

\u2014 Hydroxyl-rich sugars capture water through extensive hydrogen bonding<\/p>\n

\u2014 Their small molecular size keeps them active in and around corneocytes<\/p>\n

\u2014 The skin’s own design principle: many small polar molecules locking water where it matters<\/p>\n

Sources \u2014 Fowler, Pract. Dermatol., 2012 \u00b7 Rawlings & Harding, Dermatol. Ther., 2004 \u00b7 Verdier-S\u00e9vrain & Bont\u00e9, J. Cosmet. Dermatol., 2007<\/p>\n

04 \u00b7 MECHANISM OF ACTION \u00b7 \u4f5c\u7528\u673a\u5236<\/p>\n

A Multi-Dimensional Hydration Mechanism<\/h2>\n

<\/p>\n\n\n\n\n
01Bind waterLow-molecular-weight sugar molecules present a dense array of hydroxyl groups, forming an extensive hydrogen-bond network with water molecules.<\/td>\n02Hold waterAs hygroscopic molecules, sugars build a water reservoir at the skin and hair surface, buffering fluctuations in ambient humidity.<\/td>\n<\/tr>\n
03Reduce surface water lossA water-rich surface slows evaporation from the stratum corneum, helping skin preserve its own water content.<\/td>\n04Support barrier comfortHydrated corneocytes stay supple; the skin surface remains smooth, soft, and comfortable throughout the day.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Mechanistic basis drawn from carbohydrate chemistry and skin hydration research \u2014 Verdier-S\u00e9vrain & Bont\u00e9, 2007 \u00b7 Fluhr et al., 2023<\/p>\n

05 \u00b7 EFFICACY \u2014 HYDRATION \u00b7 \u529f\u6548\u8bc1\u636e \u00b7 \u4fdd\u6e7f<\/p>\n

Hydration & Water Retention<\/h2>\n

From isolated stratum corneum to human volunteers, saccharide systems consistently improve the skin’s ability to bind and retain water across multiple models.<\/p>\n

A natural sugar-derived humectant complex significantly enhanced bound-water capacity within the stratum corneum and modulated its structural parameters.<\/p>\n

In vitro Raman spectroscopy \u00b7 human stratum corneum\u3000\uff5c\u3000Fluhr et al., J. Biophotonics, 2023<\/p>\n

A serum containing 7% galacto-oligosaccharides significantly improved skin water retention (Corneometer measurement, p < 0.05 vs. control base).<\/p>\n

Randomized controlled trial \u00b7 N=60 \u00b7 8 weeks\u3000\uff5c\u3000Hong et al., J. Pers. Med., 2020<\/p>\n

Ten hygroscopic humectants (common moisturizing-cream types) significantly increased water retention in treated human stratum corneum, directly quantified by thermal desorption\u2013mass spectrometry.<\/p>\n

Thermal desorption\u2013mass spectrometry\u3000\uff5c\u3000Gournay et al., Int. J. Cosmet. Sci., 1995<\/p>\n

These studies evaluated saccharide systems similar to \u2014 but not identical with \u2014 PuriActives\u00ae SH50. Together they establish the class’s hydration mechanism across complementary models.<\/p>\n

06 \u00b7 EFFICACY \u2014 BARRIER \u00b7 \u529f\u6548\u8bc1\u636e \u00b7 \u5c4f\u969c<\/p>\n

Supporting the Skin Barrier<\/h2>\n

Hydration is not only about adding water \u2014 it is about maintaining a healthier water-management environment for the skin.<\/p>\n

<\/p>\n

Transepidermal water loss kept under control<\/h3>\n

In an 8-week randomized trial, the oligosaccharide serum group showed significantly smaller TEWL changes than the control group at weeks 4\u20138 (p < 0.05), with a reduced erythema index at week 8.<\/p>\n

Hong et al., J. Pers. Med., 2020<\/p>\n

Hydration supports barrier biology<\/h3>\n

Adequate stratum corneum water content underpins the enzymatic processes required for orderly desquamation and surface cohesion.<\/p>\n

Rawlings & Harding, Dermatol. Ther., 2004<\/p>\n

Supple, not tight<\/h3>\n

Humectant-saturated corneocytes stay soft, reducing the tightness and surface micro-cracking typical of dehydrated skin.<\/p>\n

Verdier-S\u00e9vrain & Bont\u00e9, J. Cosmet. Dermatol., 2007<\/p>\n

07 \u00b7 SENSORY DIMENSION \u00b7 \u611f\u5b98\u7ef4\u5ea6<\/p>\n

Skin Comfort & Sensory Benefits<\/h2>\n

Hydration is something consumers can truly feel. Water-plasticized keratin is the physical basis of softness, bounce, and a beautiful skin feel.<\/p>\n\n\n\n\n
Softer to the touchBound water lowers the glassy stiffness of surface keratin; skin yields softly under touch.<\/td>\nSmoother surfaceHydrated corneocytes lie flatter and shed more evenly, improving surface texture and light reflection.<\/td>\n<\/tr>\n
Less tightnessA water-buffered surface eases the dry, tight feeling after cleansing and in low-humidity environments.<\/td>\nComfortable after-feelSmall-molecule, water-phase humectants blend easily into light, fresh texture concepts.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

In a clinical study on sensitive atopic skin, an emulsion containing gluco-oligosaccharide and collagen tripeptide improved skin condition and tolerance parameters within 4 weeks \u2014 demonstrating that oligosaccharide-based care is well suited to reactive skin.<\/p>\n

Berardesca et al., Int. J. Cosmet. Sci., 2009<\/p>\n

08 \u00b7 FRONTIER SCIENCE \u00b7 \u524d\u6cbf\u79d1\u5b66<\/p>\n

The Skin Microbiome \u2014 A Prebiotic Frontier<\/h2>\n

Skin microbes feed on sugars. Choosing which sugars to offer them is becoming a formulation strategy.<\/p>\n

Short-chain fructo-oligosaccharides sustain the growth of beneficial Staphylococcus epidermidis while inhibiting Cutibacterium acnes and Staphylococcus aureus; in a reconstructed human epidermis model, 1% scFOS tilted microbial competition toward S. epidermidis.<\/p>\n

Selective utilization \u00b7 in vitro + reconstructed epidermis\u3000\uff5c\u3000Le Bourgot et al., Sci. Rep., 2022<\/p>\n

Galacto-oligosaccharides demonstrated prebiotic potential on the skin microbiota, with diffusion properties suited to topical delivery.<\/p>\n

Prebiotic potential \u00b7 skin microbiota\u3000\uff5c\u3000Petrov et al., Int. J. Cosmet. Sci., 2022<\/p>\n

An oligosaccharide-containing serum increased microbial diversity (Shannon index) after 8 weeks and reduced S. aureus abundance, while hydration parameters improved in parallel.<\/p>\n

Human randomized controlled trial \u00b7 facial skin\u3000\uff5c\u3000Hong et al., J. Pers. Med., 2020<\/p>\n

These effects were demonstrated for specific oligosaccharide structures. As a fermentable sugar substrate of the same class, PuriActives\u00ae SH50 offers a scientifically coherent platform for microbiome-friendly formulations.<\/p>\n

09 \u00b7 BEYOND SKIN \u00b7 \u627f\u524d\u542f\u540e \u00b7 \u8d85\u8d8a\u76ae\u80a4<\/p>\n

From Skin to Hair \u2014 The Same Water Physics<\/h2>\n

Hair is keratin too. The water-binding logic that works on skin transfers directly to the hair fiber.<\/p>\n

<\/p>\n

Water is hair’s plasticizer<\/h3>\n

Bound water molecules sit between keratin chains, keeping the fiber flexible; dry hair is markedly harder and more brittle.<\/p>\n

Robbins, Chemical and Physical Behavior of Human Hair, Springer, 2012<\/p>\n

Humidity changes mechanical behavior<\/h3>\n

Hair’s bending and recovery behavior depends strongly on humidity \u2014 evidence that internal water content dominates hand feel and style retention.<\/p>\n

Wortmann et al., J. Appl. Polym. Sci., 2009<\/p>\n

Humectants buffer humidity swings<\/h3>\n

Hygroscopic actives moderate the rate at which fibers gain and lose water with ambient humidity, smoothing out moisture extremes.<\/p>\n

Yu et al., Mater. Sci. Eng. C, 2017<\/p>\n

10 \u00b7 HAIR CARE \u00b7 \u62a4\u53d1\u5e94\u7528<\/p>\n

PuriActives\u00ae SH50 Hair-Care Benefits<\/h2>\n

A small-molecule humectant delivering four tangible improvements to hair feel and behavior.<\/p>\n\n\n\n\n
Moisture balanceHygroscopic sugar molecules attract and hold water inside and on the fiber, buffering moisture loss in dry air.<\/td>\nSoftness & supplenessWater-plasticized fibers bend without breaking \u2014 the mechanical root of soft, bouncy hair.<\/td>\n<\/tr>\n
Smooth combingBalanced internal moisture helps cuticles lie flatter, easing combing and reducing frizz and flyaway.<\/td>\nDaily protectionBy moderating humidity-driven swell\u2013shrink cycles, hydration reduces hygral fatigue damage.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Mechanistic basis: humidity-sensitive hair mechanics (Yu et al., Mater. Sci. Eng. C, 2017; Wortmann et al., J. Appl. Polym. Sci., 2009) and hair\u2013water relations (Robbins, Springer, 2012; Kanlayavattanakul & Lourith, Springer, 2015).<\/p>\n

11 \u00b7 FOR FORMULATORS \u00b7 \u81f4\u914d\u65b9\u5e08<\/p>\n

Formulation Value<\/h2>\n

Water-phase addition \u2014 simple and direct<\/h3>\n

Fully water-compatible small molecules \u2014 add directly to the emulsion water phase, or to aqueous serums, mists, and shampoos. No solubilizers, no heating process.<\/p>\n

Broad format compatibility<\/h3>\n

Leave-on and rinse-off, emulsified and purely aqueous systems, skin and hair \u2014 one INCI covers facial serums, moisturizers, sheet masks, scalp essences, shampoos, conditioners, and hair masks.<\/p>\n

Synergy logic<\/h3>\n

Naturally pairs with glycerin and hyaluronic acid (multi-size hydration); synergizes with \u03b2-glucans, amino acids (NMF-style blends), ceramides (hydration + lipid repair), and conditioning polymers in hair-care systems.<\/p>\n

<\/p>\n

Use levels:<\/b> maximum reported concentrations \u2014 4.6% rinse-off (US industry survey, CIR 2025); 3% leave-on (China IECIC).<\/p>\n

Within these reported use levels, PuriActives\u00ae SH50 is assessed as safe as used (CIR, Int. J. Toxicol., 2025) and is listed in China’s IECIC inventory.<\/p>\n

12 \u00b7 APPLICATIONS \u00b7 \u5e94\u7528\u573a\u666f<\/p>\n

Application Directions<\/h2>\n

Skincare<\/h3>\n

Hydrating serums & essences<\/b> \u2014 fast-absorbing water-phase hydration forming the formula’s moisture backbone.<\/p>\n

Daily moisturizers & barrier creams<\/b> \u2014 sustained surface hydration and comfort in leave-on formulas.<\/p>\n

Sheet & sleeping masks<\/b> \u2014 high-dose water delivery in intensive-care concepts.<\/p>\n

Facial mists & toners<\/b> \u2014 light, non-sticky all-day water replenishment.<\/p>\n

Sensitive-skin lines<\/b> \u2014 gentle, sugar-based hydration with a well-documented safety record.<\/p>\n

After-sun & post-procedure care<\/b> \u2014 hydration support for stressed, dehydrated skin.<\/p>\n

Men’s care<\/b> \u2014 zero-burden hydration with no occlusive greasiness.<\/p>\n

Body lotions & hand care<\/b> \u2014 everyday barrier hydration at economical use levels.<\/p>\n

Hair & Scalp Care<\/h3>\n

Moisturizing shampoos<\/b> \u2014 surface-substantive hydration that remains after rinse-off.<\/p>\n

Conditioners & hair masks<\/b> \u2014 water-plasticized softness and improved combability.<\/p>\n

Leave-in sprays & hair serums<\/b> \u2014 lasting moisture balance and frizz management.<\/p>\n

Scalp tonics & essences<\/b> \u2014 scalp hydration is the foundation of comfort.<\/p>\n

Curly & textured hair care<\/b> \u2014 keeping moisture where it is needed most.<\/p>\n

Anti-dryness repair lines<\/b> \u2014 buffering the humidity swings that drive hygral fatigue.<\/p>\n

13 \u00b7 STARTING POINTS \u00b7 \u5f00\u53d1\u8d77\u70b9<\/p>\n

Formulation Inspiration<\/h2>\n\n\n\n\n
Water-Barrier Hydrating SerumRole of SH50: 1\u20133% to build a multi-layer hydration backbone, within reported use levels.Pair with: hyaluronic acid, glycerin, panthenol.Positioning: a daily hydrating serum for all skin types.<\/td>\n24-Hour Moisturizing CreamRole of SH50: continuous water supply in the emulsion water phase.Pair with: ceramides, squalane, shea butter.Positioning: a barrier-comfort cream for day and night.<\/td>\n<\/tr>\n
Scalp Comfort EssenceRole of SH50: scalp hydration and fermentable-sugar care in a leave-on water-based formula.Pair with: niacinamide, caffeine, gentle soothing agents.Positioning: a light, leave-on scalp treatment.<\/td>\nHydrating Repair Hair MaskRole of SH50: replenishing fiber moisture in an intensive rinse-off base.Pair with: cationic conditioners, hydrolyzed proteins, plant oils.Positioning: a weekly deep-hydration treatment.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

These concepts are starting points for development discussions; suggested dosages remain within the reported cosmetic use concentrations for saccharide hydrolysate.<\/p>\n

14 \u00b7 SUMMARY \u00b7 \u6838\u5fc3\u603b\u7ed3<\/p>\n

Why PuriActives\u00ae SH50<\/h2>\n

01\u3000Advanced water management.<\/b> A low-molecular-weight saccharide humectant system that binds water through dense hydroxyl chemistry and keeps it in the stratum corneum.<\/p>\n

02\u3000Barrier support.<\/b> Hydration is structural: adequate water content supports desquamation, surface cohesion, and controlled water loss.<\/p>\n

03\u3000Consumer-perceivable comfort.<\/b> Softer touch, smoother surface, less tightness \u2014 the sensory signature of hydrated skin and hair.<\/p>\n

04\u3000Skin + hair in one.<\/b> One INCI, two categories: the same water-binding logic serves facial, body, scalp, and hair care.<\/p>\n

05\u3000Formulation-friendly.<\/b> Simple water-phase addition, no format restrictions, globally compliant \u2014 CIR assessed safe as used, FDA GRAS background, listed in China IECIC.<\/p>\n

What it is \u2014 a purified saccharide system\u3000\u00b7\u3000Why it matters \u2014 water defines skin and hair quality\u3000\u00b7\u3000Why choose it \u2014 simple, safe, versatile<\/p>\n

15 \u00b7 EVIDENCE BASE \u00b7 \u8bc1\u636e\u57fa\u7840<\/p>\n

Scientific References<\/h2>\n

[1] Johnson W Jr, Bergfeld WF, Belsito DV, et al. Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used in Cosmetics. Int. J. Toxicol. 2025; 44(4_suppl): 93S\u2013120S. DOI: 10.1177\/10915818251384580<\/p>\n

[2] Rawlings AV, Harding CR. Moisturization and skin barrier function. Dermatol. Ther. 2004; 17(Suppl. 1): 43\u201348. DOI: 10.1111\/j.1396-0296.2004.04S1005.x<\/p>\n

[3] Fowler JF Jr. Understanding the role of natural moisturizing factor in skin hydration. Pract. Dermatol. 2012; 9: 36\u201340.<\/p>\n

[4] Verdier-S\u00e9vrain S, Bont\u00e9 F. Skin hydration: a review on its molecular mechanisms. J. Cosmet. Dermatol. 2007; 6(2): 75\u201382. DOI: 10.1111\/j.1473-2165.2007.00300.x<\/p>\n

[5] Fluhr JW, Tfayli A, Darlenski R, et al. Glycerol and natural sugar-derived complex modulate differentially stratum corneum water-binding properties and structural parameters in an in vitro Raman-desorption model. J. Biophotonics 2023; 16(1): e202200201. DOI: 10.1002\/jbio.202200201<\/p>\n

[6] Gournay A, Navarro R, Mathieu J, Rivi\u00e8re M. Water retention of treated stratum corneum measured by a coupling method: thermal desorption\u2013mass spectrometry. Int. J. Cosmet. Sci. 1995; 17(4): 165\u2013172.<\/p>\n

[7] Hong KB, et al. Changes in the diversity of human skin microbiota to cosmetic serum containing prebiotics: results from a randomized controlled trial. J. Pers. Med. 2020; 10(3): 91. DOI: 10.3390\/jpm10030091<\/p>\n

[8] Berardesca E, Abril E, Serio M, Cameli N. Effects of topical gluco-oligosaccharide and collagen tripeptide F in the treatment of sensitive atopic skin. Int. J. Cosmet. Sci. 2009; 31(4): 271\u2013277. DOI: 10.1111\/j.1468-2494.2009.00495.x<\/p>\n

[9] Le Bourgot C, Meunier C, Gaio E, et al. Effects of short chain fructo-oligosaccharides on selected skin bacteria. Sci. Rep. 2022; 12: 9702. DOI: 10.1038\/s41598-022-13093-5<\/p>\n

[10] Petrov A, \u0106orovi\u0107 M, Milivojevi\u0107 A, et al. Prebiotic effect of galacto-oligosaccharides on the skin microbiota and determination of their diffusion properties. Int. J. Cosmet. Sci. 2022; 44(3): 309\u2013319. DOI: 10.1111\/ics.12778<\/p>\n

[11] Zeng M, Li Y, Cheng J, Wang J, Liu Q. Prebiotic oligosaccharides in skin health: benefits, mechanisms, and cosmetic applications. Antioxidants 2025; 14(6): 754. DOI: 10.3390\/antiox14060754<\/p>\n

[12] Yu Y, Yang W, Wang B, Meyers MA. Structure and mechanical behavior of human hair. Mater. Sci. Eng. C 2017; 73: 152\u2013163. DOI: 10.1016\/j.msec.2016.12.008<\/p>\n

[13] Wortmann FJ, Stapels M, Chandra L. Humidity-dependent bending recovery and relaxation of human hair. J. Appl. Polym. Sci. 2009; 113(5): 3336\u20133344. DOI: 10.1002\/app.30336<\/p>\n

[14] Robbins CR. Chemical and Physical Behavior of Human Hair. 5th ed. Berlin: Springer; 2012.<\/p>\n

[15] Kanlayavattanakul M, Lourith N. Biopolysaccharides for skin hydrating cosmetics. In: Polysaccharides. Cham: Springer; 2015. p. 1867\u20131892. DOI: 10.1007\/978-3-319-16298-0_29<\/p>\n

Disclaimer<\/h3>\n

This document is prepared by PuriPharm Co., Ltd. for technical communication on cosmetic ingredients only and does not constitute any drug or medical claim. Third-party literature data are cited as technical background; the cited studies evaluated saccharide systems of the same class as, but not identical with, this product. Customers should independently verify the suitability and regulatory compliance of their finished formulations. PuriActives\u00ae is a trademark of PuriPharm Co., Ltd.<\/p>\n

PURIPHARM CO., LTD.<\/p>\n

PuriActives\u00ae SH50<\/h2>\n

Smarter sugar science for modern beauty \u2014 skin & hair hydration, from molecule to market.<\/p>\n

INCI \u2014 SACCHARIDE HYDROLYSATE \u00b7 CAS 8013-17-0<\/p>\n

PuriPharm Co., Ltd. \u2014 Technical Product Report<\/p>\n","protected":false},"excerpt":{"rendered":"

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