{"id":1423,"date":"2026-10-02T21:45:44","date_gmt":"2026-10-02T13:45:44","guid":{"rendered":"http:\/\/www.puriactives.com\/en\/?p=1423"},"modified":"2026-10-02T21:45:44","modified_gmt":"2026-10-02T13:45:44","slug":"puriactives-znhc","status":"publish","type":"post","link":"http:\/\/www.puriactives.com\/en\/?p=1423","title":{"rendered":"PuriActives\u00ae ZnHC"},"content":{"rendered":"<p>PURIPHARM CO. LTD.<\/p>\n<h2>PuriActives\u00ae ZnHC<\/h2>\n<p>Zinc Hydrolyzed Collagen<\/p>\n<p><b>The Science and Technology of Skin &amp; Hair-Fiber Conditioning<\/b><\/p>\n<p>&#8220;Condition the surface, reshape the environment.&#8221;<\/p>\n<p><b>INCI NAME<\/b>\u3000ZINC HYDROLYZED COLLAGEN<\/p>\n<p>01 \u00b7 PLATFORM POSITIONING<\/p>\n<h2>A New Perspective on Protein Conditioning<\/h2>\n<p>More than hydrolyzed collagen<\/p>\n<p>The value of conventional hydrolyzed collagen centers on conditioning, hydration, and surface interaction. PuriActives\u00ae ZnHC adds zinc functionality on top of this peptide platform \u2014 building a differentiated ingredient story that extends from skin conditioning to sebum balance and scalp care.<\/p>\n<p><b>Six directions:<\/b> skin conditioning \u00b7 water management \u00b7 sebum balance \u00b7 pore appearance \u00b7 hair-fiber conditioning \u00b7 scalp care<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-9d58feda754ee1316d47a32e160266f0~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-d6de7328aa0241a51cb7afa581ebd8af&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"776\" data-rawheight=\"449\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-9d58feda754ee1316d47a32e160266f0~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-2968ffbee279259d61ec85d97a22b83d&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2089467710417719625\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-bcd34dab858804f29865c94656b6c218~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951523&amp;auth_key=1790951523-0-0-9fd7f7a707a812868af0a40e46fa5d5d&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 01 \u2014 Conceptual fusion of two functional platforms. Chemical concept illustration only; not a specific molecular structure.<\/p>\n<p>01 \u00b7 PLATFORM POSITIONING<\/p>\n<h2>What Is Zinc Hydrolyzed Collagen?<\/h2>\n<p>Zinc hydrolyzed collagen is the zinc-bound derivative of hydrolyzed collagen peptides \u2014 uniting a peptide-rich conditioning base with the functionality of Zn2+.<\/p>\n<p><b>Controlled hydrolysis<\/b><\/p>\n<p>Native collagen is degraded under controlled conditions into lower-molecular-weight peptide fractions \u2014 improving processability in aqueous systems and surface-interaction capability.<\/p>\n<p><b>Zinc binding<\/b><\/p>\n<p>Side-chain functional groups on the peptide backbone \u2014 carboxyl, amino, and hydroxyl \u2014 offer potential coordination environments for Zn2+ ions. No single defined molecular formula is implied.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-9dcc97ff92574adf25a2c4fefffb616c~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-70868dfb74327b460f200b2a9e5837dc&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"878\" data-rawheight=\"416\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-9dcc97ff92574adf25a2c4fefffb616c~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-c45eae1e402a51f0a04228f2f5601cef&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-d14b161ba8f3e873e8e47a32dbd9c85a~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-eaa9af4f17ac86a86fdc17e139dbc567&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 02 \u2014 From collagen fiber to zinc-bound peptide network. Dashed lines indicate coordination \u2014 conceptual illustration, not a structural formula.<\/p>\n<p>01 \u00b7 PLATFORM POSITIONING<\/p>\n<h2>The Functional Architecture of PuriActives\u00ae ZnHC<\/h2>\n<p>Four functions, one peptide\u2013mineral architecture \u2014 across skin, scalp, and hair fiber<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-d897c17119a1d4ed2b9622459f6cf31e~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-acae090a005892f85edd7662719041d4&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"810\" data-rawheight=\"534\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-d897c17119a1d4ed2b9622459f6cf31e~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-7b6da5c91b83a54b64043c0110fb47e9&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-42c761f5510a22b6a0cf3d4983db1276~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-3c360818abca059d213a7e9e15626b67&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 03 \u2014 The four-function mechanistic architecture of the PuriActives\u00ae ZnHC platform.<\/p>\n<p>02 \u00b7 COLLAGEN PEPTIDE PLATFORM<\/p>\n<h2>Hydrolyzed Collagen \u2014 the Functional Peptide Base<\/h2>\n<p>Hydrolyzed collagen is not intact dermal collagen, but a mixture of collagen-derived peptide fractions whose performance is expressed at the skin-surface level \u2014 hydration, film formation, and conditioning.<\/p>\n<p><b>Functional Highlights<\/b><\/p>\n<p>\u203a Hygroscopic amino-acid and peptide functional groups\u3000\u203a Interaction with skin-surface water\u3000\u203a Film-forming potential and surface affinity\u3000\u203a Softness and conditioned after-feel\u3000\u203a Hair-fiber affinity and anti-static performance\u3000\u203a Established cosmetic biomaterial compatibility<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-30dcebda3a1200c5630d39fee3a550c4~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-52ff2ce83be6d16815229a2332e15d0d&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"793\" data-rawheight=\"416\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-30dcebda3a1200c5630d39fee3a550c4~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-6b32f6d19f2ba34345f33b256ae89bd6&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-8928274e04ee44912718985c4ea90178~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-b7c158e005e16b37618fbe4d54e40f32&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 04 \u2014 Peptide fraction distribution of hydrolyzed collagen (schematic). Topically applied hydrolyzed collagen does not rebuild the dermal collagen network.<\/p>\n<p><b>&#8220;Hydrolyzed collagen acts mainly at the cosmetic contact interface \u2014 supporting hydration, conditioning, and surface quality.&#8221;<\/b><\/p>\n<p>Aguirre-Cruz G, et al. Antioxidants (Basel). 2020;9(2):181. PMID: 32098294.<\/p>\n<p>02 \u00b7 COLLAGEN PEPTIDE PLATFORM<\/p>\n<h2>Water Management in the Stratum Corneum<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-1c2cdce0d749fdf99aef1ba3e2f5ab23~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-051a69ae927de3bed792f52f81b70d17&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"793\" data-rawheight=\"466\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-1c2cdce0d749fdf99aef1ba3e2f5ab23~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-ad053382dbdf87a96c89ec8b42b6df8d&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-68d7115fb799e9004d8fef4b4b62f080~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-2062c8a222af10fe106f28b5af9c3b23&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 05 \u2014 The &#8220;brick-and-mortar&#8221; model of the stratum corneum with a peptide-rich hydrating surface film (schematic).<\/p>\n<p><b>Benefit Statements<\/b><\/p>\n<p>\u203a Supports skin hydration\u3000\u203a Enhances softness\u3000\u203a Improves conditioned after-feel\u3000\u203a Helps reduce the perception of dryness and roughness<\/p>\n<p><b>1<\/b>\u3000Collagen-derived peptides\u3000\u2192\u3000<b>2<\/b>\u3000Water association + surface affinity<\/p>\n<p><b>3<\/b>\u3000Hydrated interface\u3000\u2192\u3000<b>4<\/b>\u3000Softer \/ smoother skin feel<\/p>\n<p>A hydrated interface is a surface phenomenon \u2014 peptides associate with water and the stratum corneum to improve the conditioned feel of skin.<\/p>\n<p>Supporting evidence: topical collagen literature \u2014 see References (03).<\/p>\n<p>03 \u00b7 ZINC FUNCTIONAL PLATFORM<\/p>\n<h2>Zinc \u2014 a Trace Element of Biological Significance<\/h2>\n<p>Zinc is a multifunctional bio-ion. Its biology spans enzyme catalysis, protein structure, cellular homeostasis, and epidermal function \u2014 a breadth rarely found in a cosmetic mineral ingredient.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-0ed8b4d2eadf7c1dadbb7c166dea55c4~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-3d32ca7941c550ce59be26142ba5fea5&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"827\" data-rawheight=\"534\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-0ed8b4d2eadf7c1dadbb7c166dea55c4~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-85c803a55995672730d52fde8eab00fc&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2089467710417719625\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-96c0c9eb8762444eb32867bbd8ba4585~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951523&amp;auth_key=1790951523-0-0-b04f48f6fb25cd815ededbb71681aa2b&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 06 \u2014 The zinc biology network relevant to cosmetic science (overview schematic).<\/p>\n<p><b>&#8220;In cosmetic science, zinc chemistry builds a compelling bridge between skin-surface management and cellular stress biology.&#8221;<\/b><\/p>\n<p>This page is presented as biological background for cosmetic innovation \u2014 not as medical dermatology.<\/p>\n<p>03 \u00b7 ZINC FUNCTIONAL PLATFORM<\/p>\n<h2>Zinc and Dermal-Matrix Stress Biology<\/h2>\n<p>Mechanistic evidence from a related zinc salt \u2014 in vitro human dermal fibroblasts: mechanistic context for zinc, not ingredient-specific data<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-0672d75c0b75b498a2fc1c66fc725397~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-159487b7746cbfbeb7c9ad2173deb306&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"878\" data-rawheight=\"449\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-0672d75c0b75b498a2fc1c66fc725397~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-624ef3b509c5c7e6b676870a97661c5a&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-40f181951b7a82145a976f8c785f7381~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-d8df13c8117ad836b1e2bd03ffd04fc3&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 07 \u2014 UVA \/ AP-1 \/ MMP-1 pathway and zinc intervention nodes, redrawn from the cited literature.<\/p>\n<p><b>&#8220;Appropriately delivered zinc can engage pathways related to collagen homeostasis and photo-stress biology.&#8221;<\/b><\/p>\n<p>Takino Y, Okura F, Kitazawa M, Iwasaki K, Tagami H. Int J Cosmet Sci. 2012;34(1):23\u201328. doi:10.1111\/j.1468-2494.2011.00676.x \u2014 the study used zinc pyrrolidone carboxylate (Zinc PCA), not zinc hydrolyzed collagen.<\/p>\n<p>04 \u00b7 DIRECT INGREDIENT EVIDENCE<\/p>\n<h2>Direct Evidence for Zinc Hydrolyzed Collagen<\/h2>\n<p><b>KR20250138932A<\/b><\/p>\n<p>Cosmetic composition comprising hydrolyzed collagen and zinc<\/p>\n<p>Published September 23, 2025 \u00b7 cited by publication number only<\/p>\n<p>The patent explicitly describes zinc hydrolyzed collagen and benchmarks it directly against hydrolyzed collagen in paired toner, serum, and cream formulations \u2014 reporting superior oil-control and pore-related performance at equal addition levels.<\/p>\n<p><b>Experimental Design<\/b><\/p>\n<p><b>Zinc hydrolyzed collagen\u3000vs\u3000hydrolyzed collagen<\/b> \u2014 tested across formulation formats: toner \u00b7 serum \u00b7 cream<\/p>\n<p>Addition levels evaluated (as % of the tested collagen composition): <b>0.1% \u00b7 1% \u00b7 3% \u00b7 10%<\/b><\/p>\n<p>Compared with matched hydrolyzed-collagen formulas at equal levels, the zinc hydrolyzed collagen formulas performed better on oil-control and pore-related measures.<\/p>\n<p><b>One of the strongest pieces of ingredient-level direct evidence in this dossier.<\/b><\/p>\n<p>Applicant information deliberately omitted; this dossier cites the patent literature by publication number only.<\/p>\n<p>04 \u00b7 DIRECT INGREDIENT EVIDENCE<\/p>\n<h2>Sebum Balance \u2014 Direct Ingredient Evidence<\/h2>\n<p>Formula-comparison data reported in the patent<\/p>\n<p><b>Method \u2014 as reported in the patent<\/b><\/p>\n<p><b>1<\/b>\u3000Full-face imaging under standardized conditions\u3000\u3000<b>2<\/b>\u3000T-zone selected for sebum-related analysis<\/p>\n<p><b>3<\/b>\u3000ZnHC formula versus matched hydrolyzed-collagen formula\u3000\u3000<b>4<\/b>\u3000Toner, serum, and cream formats evaluated in parallel<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-3351a09df1c3fd19761b48e6c47429c0~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-f9f028290c701fba6cd20f22d97c81d5&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"831\" data-rawheight=\"444\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-3351a09df1c3fd19761b48e6c47429c0~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-2584a67dac7e275c296ae97e05392a48&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-7e8d3819683c896cecfbc4d33d35ed06~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-ee0ea7851b955ad2de7d2e7bfaba69de&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 08 \u2014 Directional schematic drawn from the comparative sebum evaluation reported in Figure 1 of KR20250138932A. Effect direction per the patent report; axis values not reproduced.<\/p>\n<p><b>&#8220;Across toner, serum, and cream architectures, zinc binding moves hydrolyzed collagen beyond a conditioning position toward a broader oil-balance platform.&#8221;<\/b><\/p>\n<p>04 \u00b7 DIRECT INGREDIENT EVIDENCE<\/p>\n<h2>Visible Pore Care \u2014 a Differentiated Skin Opportunity<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-95d54a4a6a3627fa16f1ea0cfe361677~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-0f0794ed9f99f41ad317dc08e16c07e4&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"782\" data-rawheight=\"444\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-95d54a4a6a3627fa16f1ea0cfe361677~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951523&amp;auth_key=1790951523-0-0-a784b8f7f5039670716dd3857a88fdf6&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2089467710417719625\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-e5319fd0b103c4fdf2e450a88f423e59~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951523&amp;auth_key=1790951523-0-0-16f2b659652935b8b8767d3b8230fa99&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 09 \u2014 Directional schematic drawn from the pore evaluation reported in Figure 2 of KR20250138932A. Effect direction per the patent report; axis values not reproduced.<\/p>\n<p><b>Method \u2014 as reported in the patent<\/b><\/p>\n<p><b>1<\/b>\u3000Full-face imaging before \/ after product use\u3000\u3000<b>2<\/b>\u3000Cheek and nose regions analyzed<\/p>\n<p><b>3<\/b>\u3000Pore-related image metrics evaluated\u3000\u3000<b>4<\/b>\u3000ZnHC versus matched hydrolyzed-collagen formulas<\/p>\n<p><b>From hydration\u3000\u2192\u3000hydration + pore appearance + sebum balance<\/b><\/p>\n<p><b>Cosmetic Benefit Statements<\/b><\/p>\n<p>\u203a Visible pore refinement\u3000\u203a Finer-looking skin texture\u3000\u203a Oil-balance support\u3000\u203a A more refined skin appearance<\/p>\n<p><b>Cosmetic appearance positioning only \u2014 no therapeutic claims such as acne treatment.<\/b><\/p>\n<p>04 \u00b7 DIRECT INGREDIENT EVIDENCE<\/p>\n<h2>How Zinc Rewrites the Hydrolyzed-Collagen Story<\/h2>\n<p>&#8220;From passive conditioning to multifunctional conditioning.&#8221;<\/p>\n<table data-draft-node=\"block\" data-draft-type=\"table\" data-size=\"normal\" data-row-style=\"normal\">\n<tbody>\n<tr>\n<th>Functional Dimension<\/th>\n<th>Hydrolyzed collagen<\/th>\n<th>Zinc hydrolyzed collagen<\/th>\n<\/tr>\n<tr>\n<td>Hydration &amp; water support<\/td>\n<td>\u25cf<\/td>\n<td>\u25cf<\/td>\n<\/tr>\n<tr>\n<td>Surface conditioning &amp; film formation<\/td>\n<td>\u25cf<\/td>\n<td>\u25cf<\/td>\n<\/tr>\n<tr>\n<td>Softness &amp; smoothness<\/td>\n<td>\u25cf<\/td>\n<td>\u25cf<\/td>\n<\/tr>\n<tr>\n<td>Hair-fiber affinity<\/td>\n<td>\u25cf<\/td>\n<td>\u25cf<\/td>\n<\/tr>\n<tr>\n<td>Sebum-management opportunity<\/td>\n<td>\u2014<\/td>\n<td>\u25cf<\/td>\n<\/tr>\n<tr>\n<td>Visible pore-care positioning<\/td>\n<td>\u2014<\/td>\n<td>\u25cf<\/td>\n<\/tr>\n<tr>\n<td>Zinc-related biological significance<\/td>\n<td>\u2014<\/td>\n<td>\u25cf<\/td>\n<\/tr>\n<tr>\n<td>Skin + scalp multifunctionality<\/td>\n<td>\u2014<\/td>\n<td>\u25cf<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>The added dimensions are evidence-driven \u2014 anchored in the KR20250138932A comparison data and the zinc mechanism literature, not in claim language.<\/p>\n<p>05 \u00b7 PORE &amp; TEXTURE CARE<\/p>\n<h2>Pore Care Is More Than &#8220;Astringency&#8221;<\/h2>\n<p>Five factors behind visible pores<\/p>\n<p><b>01\u3000Sebaceous gland activity<\/b> \u2014 the flux of oil through the follicle<\/p>\n<p><b>02\u3000Surface topography<\/b> \u2014 light reflection and micro-texture<\/p>\n<p><b>03\u3000Hydration status<\/b> \u2014 stratum-corneum hydration and surface plumpness<\/p>\n<p><b>04\u3000Elasticity &amp; structural support<\/b> \u2014 firmness and recoil around the follicle<\/p>\n<p><b>05\u3000Follicle structure<\/b> \u2014 the size, shape, and density of pore openings<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-a226c802eaa99cc8de51b1c16946f448~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-5a9672e798ded11313dd051516c1cddd&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"810\" data-rawheight=\"539\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-a226c802eaa99cc8de51b1c16946f448~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-4369a7dd18fb4301e99664ed97cfc613&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False&amp;draft_token=2089467710417719625\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-f63e0c271bf07e703a81b4608b7ff2a8~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951523&amp;auth_key=1790951523-0-0-79890cae5785ac4d4f9ada8191a099ab&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 10 \u2014 Follicle cross-section (schematic). Pore appearance is managed at the surface level; no permanent anatomical change is claimed.<\/p>\n<p><b>Where ZnHC Fits<\/b><\/p>\n<p>Sebum balance + surface conditioning + hydration + skin texture<\/p>\n<p>\u2713\u3000&#8221;Helps refine the appearance of visible pores&#8221;\u3000\u3000\u2715\u3000&#8221;Closes pores&#8221;<\/p>\n<p>Positioning targets the cosmetic appearance of pores \u2014 not permanent pore reduction.<\/p>\n<p>05 \u00b7 PORE &amp; TEXTURE CARE<\/p>\n<h2>A Texture Platform for Combination and Oily Skin<\/h2>\n<p>Translating scientific language into formulation and marketing language<\/p>\n<p><b>Target Skin Profiles<\/b><\/p>\n<p>Oily \u00b7 combination \u00b7 visible pores \u00b7 rough texture \u00b7 dehydrated-oily \u00b7 urban-stressed skin<\/p>\n<p><b>Balance<\/b>\u3000Sebum-balance support in oily zones<\/p>\n<p><b>Refine<\/b>\u3000Refinement of visible pores and texture<\/p>\n<p><b>Hydrate<\/b>\u3000Peptide-based water management<\/p>\n<p><b>Smooth<\/b>\u3000A softer, smoother conditioned skin feel<\/p>\n<p><b>Product Concepts for Formulators<\/b><\/p>\n<p>\u203a Pore-refining serum\u3000\u203a Balancing serum\u3000\u203a Lightweight gel-cream\u3000\u203a Hydrating oil-control toner\u3000\u203a Texture-conditioning treatment\u3000\u203a Post-cleanse conditioning essence<\/p>\n<p>Positioning language stays B2B and cosmetic in nature; final claims depend on the finished formulation.<\/p>\n<p>06 \u00b7 HAIR-FIBER CONDITIONING<\/p>\n<h2>From Skin to Hair \u2014 Why Protein Affinity Matters<\/h2>\n<p><b>&#8220;Hydrolyzed proteins are valued in hair care because low-molecular-weight peptide fractions can interact with damaged keratin surfaces.&#8221;<\/b><\/p>\n<p><b>Damaged cuticle<\/b> \u2014 bleaching, heat, and combing lift and erode the cuticle scales.<\/p>\n<p><b>Peptide adsorption<\/b> \u2014 peptide fractions preferentially adsorb at damaged surface sites.<\/p>\n<p><b>Conditioned surface<\/b> \u2014 a conditioned surface with improved feel and manageability.<\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-7bba412ebf1c3b1f20cbd407f07da5ed~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-8d285c78f763979d1a28d8ff9602876d&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"878\" data-rawheight=\"356\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-7bba412ebf1c3b1f20cbd407f07da5ed~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-ef44d23b4a5336112c31522203a925b6&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-388a77a64c41886fa625d174d8dc0e46~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-1d74fc37fcccd0f2cd9b21e564b03b55&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 11 \u2014 Peptide affinity at the damaged cuticle (schematic).<\/p>\n<p>Classic substantivity evidence: Turowski A, et al. Substantivity to hair and skin of 125I-labelled collagen hydrolysates under application-simulating conditions. Int J Cosmet Sci. 1985;7:71\u201384. doi:10.1111\/j.1467-2494.1985.tb00398.x<\/p>\n<p><b>Surface adsorption is a cosmetic conditioning mechanism \u2014 not permanent structural repair.<\/b><\/p>\n<p>06 \u00b7 HAIR-FIBER CONDITIONING<\/p>\n<h2>Hair-Fiber Conditioning \u2014 Surface Science in Practice<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-11aeadbc3fe2d0a2014767ab7a5d07a9~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-beec53043bf55200bdd7d586ca95f97a&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"827\" data-rawheight=\"416\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-11aeadbc3fe2d0a2014767ab7a5d07a9~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-9653d761642ed2a156607e3d18c9cbac&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-76617c26a3ea2d41eb2a8a1002ff7330~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-2ba2e6e0de1de3950c9485af1056af63&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 12 \u2014 SEM-style cuticle schematic (redrawn illustration, not micrograph data). Peptide deposition preferentially occurs at damaged sites.<\/p>\n<p>Protein-hydrolysate conditioning is a surface materials-science question \u2014 deposition, affinity, and film behavior at the fiber surface, unrelated to follicle biology.<\/p>\n<p><b>Conditioning Outcomes<\/b><\/p>\n<p>\u203a Anti-static conditioning\u3000\u203a Improved surface feel\u3000\u203a Reduced roughness\u3000\u203a Better combability\u3000\u203a Softness and shine potential\u3000\u203a Conditioning of damaged hair<\/p>\n<p><b>Outcomes Are Modulated By<\/b><\/p>\n<p>Molecular-weight distribution \u00b7 peptide charge and degree of fiber damage \u00b7 formulation environment \u00b7 rinse-off versus leave-on contact<\/p>\n<p>06 \u00b7 HAIR-FIBER CONDITIONING<\/p>\n<h2>Damaged Hair Needs More Conditioning<\/h2>\n<p><b>Processing &amp; Treatment Stressors<\/b><\/p>\n<p>Bleaching \u00b7 coloring \u00b7 perming \u00b7 heat \u00b7 UV \u00b7 mechanical combing<\/p>\n<p><b>What Increases at the Fiber Surface<\/b><\/p>\n<p>Cuticle irregularity \u00b7 surface friction \u00b7 porosity \u00b7 protein loss \u00b7 static charge \u00b7 roughness<\/p>\n<p><b>The Conditioning Response<\/b><\/p>\n<p><b>Peptide-rich conditioning<\/b> \u2014 preferential interaction with damaged surfaces<\/p>\n<p>Improvement in cosmetic surface quality<\/p>\n<p>Supported by the peer-reviewed hair-fiber conditioning literature (see References). Oral collagen-supplementation studies are not used as evidence for topical hair-fiber claims.<\/p>\n<p>07 \u00b7 SCALP &amp; PORTFOLIO<\/p>\n<h2>Scalp Care \u2014 Where Skin Science Meets Hair Science<\/h2>\n<p><b>&#8220;The scalp is skin \u2014 with an active sebaceous environment.&#8221;<\/b><\/p>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-31236b00c19ed571e0560312b2aab28a~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-33c297556aea5e0a9e93c2bc17325fc2&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"844\" data-rawheight=\"500\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-31236b00c19ed571e0560312b2aab28a~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-9919eccdbe47d1b5983f749793e2139c&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-3898f1df6516ea452940a1d14c9b64df~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-544e5812151eee608fec761b5514d849&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p>Figure 13 \u2014 Scalp mechanism map: four converging care pathways.<\/p>\n<p><b>Positioning<\/b><\/p>\n<p>\u203a Oily-scalp care\u3000\u203a Scalp hydration\u3000\u203a Scalp conditioning\u3000\u203a Sebum-balance concepts\u3000\u203a Scalp comfort\u3000\u203a Hair-root environment<\/p>\n<p><b>Potential Applications<\/b><\/p>\n<p>Scalp serums \u00b7 shampoos \u00b7 scalp treatments \u00b7 conditioners \u00b7 hair masks \u00b7 leave-on care<\/p>\n<p><b>No claims are made regarding the treatment of seborrheic dermatitis, hair loss, or dandruff.<\/b><\/p>\n<p>07 \u00b7 SCALP &amp; PORTFOLIO \u00b7 SIGNATURE<\/p>\n<h2>One Ingredient \u2014 Two Beauty Territories<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-15f4725b2df6bec61376b0ca2505e140~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-db53cdcd841698cbb0fa3e6af3da9433&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"844\" data-rawheight=\"517\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-15f4725b2df6bec61376b0ca2505e140~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-81626ccc0f96dd75b319ab7bdf0857fd&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-286e94664bae6a01689caaea23e7fa69~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-a23f446047084716104c3d9a4f11cab5&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p><b>&#8220;One peptide\u2013mineral platform connecting skin science and hair science.&#8221;<\/b><\/p>\n<p>08 \u00b7 FORMULATION &amp; EVIDENCE MAP<\/p>\n<h2>Formulation Opportunities<\/h2>\n<p>One ingredient, three formulation territories \u2014 from daily skincare to targeted scalp and hair systems<\/p>\n<table data-draft-node=\"block\" data-draft-type=\"table\" data-size=\"normal\" data-row-style=\"normal\">\n<tbody>\n<tr>\n<th>Skin Care<\/th>\n<th>Scalp Care<\/th>\n<th>Hair Care<\/th>\n<\/tr>\n<tr>\n<td>Toners<\/td>\n<td>Scalp essence water<\/td>\n<td>Shampoos<\/td>\n<\/tr>\n<tr>\n<td>Essence waters<\/td>\n<td>Scalp serums<\/td>\n<td>Conditioners<\/td>\n<\/tr>\n<tr>\n<td>Serums<\/td>\n<td>Balancing lotions<\/td>\n<td>Hair masks<\/td>\n<\/tr>\n<tr>\n<td>Gel-creams<\/td>\n<td>Pre-wash treatments<\/td>\n<td>Leave-in conditioners<\/td>\n<\/tr>\n<tr>\n<td>Creams<\/td>\n<td><\/td>\n<td>Repair serums \/ sprays<\/td>\n<\/tr>\n<tr>\n<td>Masks<\/td>\n<td><\/td>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b>Published Formulation Precedent<\/b><\/p>\n<p>KR20250138932A evaluated collagen compositions containing zinc hydrolyzed collagen in toner, serum, and cream prototypes at 0.1\u201310% addition. This range is cited as a published precedent only \u2014 it is not the official recommended dosage for PuriActives\u00ae ZnHC. Please refer to PuriPharm technical specifications.<\/p>\n<p>08 \u00b7 FORMULATION &amp; EVIDENCE MAP<\/p>\n<h2>Formulator&#8217;s Scientific Snapshot<\/h2>\n<table data-draft-node=\"block\" data-draft-type=\"table\" data-size=\"normal\" data-row-style=\"normal\">\n<tbody>\n<tr>\n<td>Trade name<\/td>\n<td>PuriActives\u00ae ZnHC<\/td>\n<\/tr>\n<tr>\n<td>INCI<\/td>\n<td>ZINC HYDROLYZED COLLAGEN<\/td>\n<\/tr>\n<tr>\n<td>Product platform<\/td>\n<td>Zinc-functionalized collagen-peptide conditioning system<\/td>\n<\/tr>\n<tr>\n<td>Core benefits<\/td>\n<td>Skin conditioning \u00b7 water support \u00b7 visible pore-care positioning \u00b7 sebum-balance positioning \u00b7 hair-fiber conditioning \u00b7 scalp-care support<\/td>\n<\/tr>\n<tr>\n<td>Target applications<\/td>\n<td>Skin care \u00b7 scalp care \u00b7 hair care<\/td>\n<\/tr>\n<tr>\n<td>Evidence platform<\/td>\n<td>Direct patent evidence for zinc hydrolyzed collagen \u00b7 hydrolyzed-collagen literature \u00b7 zinc-mechanism literature \u00b7 hair-substantivity literature<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b>Technical Specifications<\/b><\/p>\n<p>pH, solids content, molecular-weight distribution, zinc content, preservation system, appearance, recommended dosage, and stability data are governed by PuriPharm technical documentation. They are deliberately not reproduced in this presentation.<\/p>\n<p>08 \u00b7 FORMULATION &amp; EVIDENCE MAP<\/p>\n<h2>The Evidence Map \u2014 from Direct Data to Mechanistic Support<\/h2>\n<p><img src=\"https:\/\/pic-out.zhimg.com\/v2-59897c08304d48b9a1d40169df0a4d72~resize:1440:q75.png?animatedImageAutoPlay=false&amp;animatedImagePlayCount=1&amp;auth_key=1790948169-0-0-4c958b577d86ee9aaf2c61e386935cc7&amp;bizSceneCode=article_draft&amp;expiration=1790948169&amp;incremental=false&amp;mid=af87d0ba5943ed43c9d129c257d04f1b&amp;overTime=60&amp;precoder=false&amp;protocol=v2&amp;retryCount=3&amp;sampling=false&amp;sceneCode=editor_copy_outbound&amp;source=bfcaadb1\" data-caption=\"\" data-size=\"normal\" data-rawwidth=\"844\" data-rawheight=\"517\" data-watermark=\"original\" data-original-src=\"https:\/\/pic-private.zhihu.com\/v2-59897c08304d48b9a1d40169df0a4d72~resize:0:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-9232778aef0b75d0706761863950121c&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-watermark-src=\"https:\/\/pic-private.zhihu.com\/v2-d94b57dacc4fb061dc5e69ca3dd94c52~resize:1440:q75.png?source=1f5c5e47&amp;expiration=1790951522&amp;auth_key=1790951522-0-0-519c19c5c849889bc4cd8b78ee03e577&amp;protocol=v2&amp;sampling=False&amp;animatedImagePlayCount=1&amp;overTime=60&amp;incremental=False&amp;sceneCode=article_draft_web&amp;animatedImageAutoPlay=False&amp;retryCount=3&amp;precoder=False\" data-private-watermark-src=\"\" \/><\/p>\n<p><b>Level 1 \u2014 Direct ZnHC evidence<\/b>\u3000KR20250138932A \u2014 oil-control and pore-related performance in toner, serum, and cream formulations.<\/p>\n<p><b>Level 2 \u2014 Hydrolyzed-collagen evidence<\/b>\u3000Topical hydration, surface conditioning, skin and hair substantivity (Aguirre-Cruz 2020; Turowski 1985).<\/p>\n<p><b>Level 3 \u2014 Zinc-mechanism evidence<\/b>\u3000Matrix-stress and sebaceous-biology context (Takino 2012 \u2014 Zinc PCA, in vitro).<\/p>\n<p><b>Level 4 \u2014 Formulation science<\/b>\u3000Peptide adsorption, hair-fiber interaction, and surface-conditioning science.<\/p>\n<p><b>Indirect evidence supports mechanism and ingredient-class context \u2014 it is not clinical proof of finished-product performance.<\/b><\/p>\n<p>08 \u00b7 FORMULATION &amp; EVIDENCE MAP \u00b7 ONE-PAGE STORY<\/p>\n<h2>PuriActives\u00ae ZnHC \u2014 the Product Story on One Page<\/h2>\n<p><b>Condition<\/b> \u2014 collagen-derived peptides support the surface quality of skin and hair.<\/p>\n<p><b>Hydrate<\/b> \u2014 a peptide-rich interface supports water retention and softness.<\/p>\n<p><b>Balance<\/b> \u2014 zinc functionality extends the platform to sebum and pore care.<\/p>\n<p><b>Connect<\/b> \u2014 one ingredient linking skin, scalp, and hair-care innovation.<\/p>\n<p><b>&#8220;Peptide conditioning, empowered by zinc.&#8221;<\/b><\/p>\n<p>09 \u00b7 REFERENCES<\/p>\n<h2>Scientific References<\/h2>\n<p>Core literature supporting this dossier, ranked by evidentiary proximity to zinc hydrolyzed collagen<\/p>\n<p><b>01<\/b>\u3000KR20250138932A. Cosmetic composition comprising hydrolyzed collagen and zinc. Korean patent publication, September 23, 2025 \u2014 cited by publication number only. Ingredient-level direct evidence: comparative oil-control and pore-related evaluation in toner, serum, and cream formulations.<\/p>\n<p><b>02<\/b>\u3000Takino Y, Okura F, Kitazawa M, Iwasaki K, Tagami H. Zinc L-pyrrolidone carboxylate inhibits the UVA-induced production of matrix metalloproteinase-1 by in vitro cultured skin fibroblasts, whereas it enhances their collagen synthesis. International Journal of Cosmetic Science. 2012;34(1):23\u201328. doi:10.1111\/j.1468-2494.2011.00676.x<\/p>\n<p><b>03<\/b>\u3000Aguirre-Cruz G, Le\u00f3n-L\u00f3pez A, Cruz-G\u00f3mez V, Jim\u00e9nez-Alvarado R, Aguirre-\u00c1lvarez G. Collagen Hydrolysates for Skin Protection: Oral Administration and Topical Formulation. Antioxidants (Basel). 2020;9(2):181. doi:10.3390\/antiox9020181. PMID: 32098294<\/p>\n<p><b>04<\/b>\u3000Turowski A, et al. Substantivity to hair and skin of 125I-labelled collagen hydrolysates under application-simulating conditions. International Journal of Cosmetic Science. 1985;7:71\u201384. doi:10.1111\/j.1467-2494.1985.tb00398.x<\/p>\n<p><b>05<\/b>\u3000Burnett CL, Bergfeld WF, Belsito DV, et al. Safety Assessment of Skin and Connective Tissue-Derived Proteins and Peptides as Used in Cosmetics. International Journal of Toxicology. 2022. doi:10.1177\/10915818221104783<\/p>\n<p>For further literature on topical collagen hydrolysates, zinc biology, and hair surface science, see the complete PuriPharm technical dossier.<\/p>\n<p>PuriActives\u00ae\uff5cProduced by PuriPharm Co. Ltd.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>PURIPHARM CO. LTD. PuriActives\u00ae ZnHC Zinc Hydrolyzed Co [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[25],"tags":[],"_links":{"self":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/posts\/1423"}],"collection":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1423"}],"version-history":[{"count":1,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/posts\/1423\/revisions"}],"predecessor-version":[{"id":1424,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=\/wp\/v2\/posts\/1423\/revisions\/1424"}],"wp:attachment":[{"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1423"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1423"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.puriactives.com\/en\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1423"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}