浦瑞生物医药技术有限公司成功获得蜂胶脂质体制备方法及应用发明专利授权

2023年7月3日，国家知识产权局正式授权湖州浦瑞生物医药技术有限公司(以下简称“浦瑞生物”)的发明专利“蜂胶脂质体的制备方法及应用”。这是浦瑞生物在功能性活性物原料领域取得的又一项重要突破，标志着公司在蜂胶生物制品研发和产业化方面迈出了关键一步。

蜂胶是一种传统的中药材，具有丰富的生物活性成分，如黄酮类、酚酸类等，对人体具有广泛的生物学活性。然而，由于蜂胶不水溶、生物利用度较低，导致其在实际应用中的局限性。为了解决这一问题，浦瑞生物科研团队将传统医学理论与现代纳米生物技术相结合，成功研发出新型蜂胶纳米脂质体产品——PuriActives®蜂胶纳米脂质体。
PuriActives®蜂胶纳米脂质体是利用新型药物递送技术将蜂胶活性物包裹在纳米脂质体中，形成一种具有高载药量、高稳定性、高溶解度的新型药物载体。该产品不仅保留了蜂胶的核心活性成分，还提高了其在人体内的生物利用度，从而增强了产品的功效。
PuriActives®蜂胶纳米脂质体具有以下显著特点：
  1. 蜂胶镇痛、消炎、抗过敏等效果显著；
  2. 以磷脂作为纳米载体，安全性高，无毒副作用；
  3. 配伍性好，方便易用，拓展了蜂胶的应用领域；
  4. 可广泛应用于皮肤护理、口腔护理、头皮护理等领域。
公司创始人杨正茂表示：“我们非常荣幸能够获得这项发明专利授权。这标志着我们的研究成果得到了国家知识产权局的高度认可。未来，我们将继续深耕功能性活性物领域，不断创新，为全球客户提供更多高品质的产品。”
PuriPharm successfully obtained the patent authorization for the invention of propolis liposome preparation method and application
On July 3, 2023, the State Intellectual Property Office officially granted PuriPharm Co., Ltd.(PuriPharm). This is another important breakthrough in the field of functional active ingredients, marking a key step in the development and industrialization of propolis biological products.
Propolis is a traditional Chinese medicine with rich bioactive components, such as flavonoids and phenolic acids, which have a wide range of biological activities for human body. However, the insolubility and low bioavailability of propolis have led to its limitations in practical applications. In order to solve this problem, the research team of PuriPharm has successfully developed a new propolis nanoliposome product, PuriActives® Propolis Nanoliposome, by combining traditional medical theory with modern nanobiotechnology.
PuriActives® Propolis Nanoliposome is a new type of drug carrier with high drug loading capacity, high stability and high solubility by using a new drug delivery technology to encapsulate propolis active substances in nanoliposomes. The product not only retains the core active ingredients of propolis, but also improves its bioavailability in the human body, thus enhancing the efficacy of the product.
PuriActives propolis nanoliposomes have the following distinctive features:
  1. Significant analgesic, anti-inflammatory and anti-allergic effects of propolis
  2. High safety and non-toxic side effects due to the use of phospholipids as nano carriers
  3. Good compatibility, convenience and ease of use, expanding the application areas of propolis
  4.  It can be widely used in skin care, oral care, scalp care and other fields.
We are very honored to be granted this invention patent,” said company founder Yang Zhengmao. This marks that our research results have been highly recognized by the State Intellectual Property Office. In the future, we will continue to deepen our efforts in the field of functional actives and continue to innovate to provide more high-quality products to our global customers.”