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NanoActive Sulfur PRODUCT DATA SHEET

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Advanced Nano-Encapsulated Bio-Derived Sulfur for Multi-Targeted Skin Solutions

Company: PuriPharm Co. Ltd.

Website: www.PuriActives.com

Contact: Service@puripharm.com | Tel: 13167223168

1. PRODUCT OVERVIEW

Sulfur is a naturally occurring nonmetal with a long-standing dermatological history of effectively treating various skin disorders. However, traditional sulfur applications are severely limited by poor water solubility, large particle sizes (2–5 μm), low bioavailability, and formulation challenges.

NanoActive Sulfur, developed by PuriPharm Co. Ltd., is a cutting-edge active ingredient that utilizes a proprietary Nano-Delivery System (NDS). By stably encapsulating highly active bio-derived sulfur into sub-30 nm lipid-based nanocarriers, it completely resolves traditional solubility and aesthetic issues. The result is a highly bioavailable, transparent, and universally compatible active that regulates sebum, reduces inflammation, and offers potent antibacterial properties for acne and scalp care.

2. COMPOSITION & INCI INFORMATION

NanoActive Sulfur is formulated using a specialized biomimetic lipid matrix designed for optimal trans-epidermal delivery. It is strictly free from added preservatives and antioxidants.

Composition Range Table:

3. TECHNICAL SPECIFICATIONS

4. TECHNOLOGY HIGHLIGHTS: THE NDS ADVANTAGE

  • Ultra-Fine Particle Size (< 30 nm): Significantly increases the specific surface area and interaction with keratinocytes, ensuring superior skin penetration and biological activity compared to traditional 2-5 μm sulfur.
  • Exceptional Formulation Flexibility: The unique hydrophilic-lipophilic structural modification allows NanoActive Sulfur to be seamlessly incorporated into lotions, creams, clear gels, and water-based formulas without precipitation.
  • Aesthetic Superiority: Unlike traditional sulfur, which is chalky and difficult to suspend, NanoActive Sulfur maintains optical clarity (forming a transparent solution at typical usage levels), leaving no residue and enabling elegant cosmetic formulations.
  • High Stability & Bioavailability: The robust phospholipid-based nanocarrier prevents aggregation, protects the active payload, and ensures targeted delivery to the sebaceous glands and follicles.

5. KEY COSMETIC BENEFITS & MECHANISM OF ACTION

A. Comprehensive Sebum Regulation & Keratolysis

Excessive sebum accumulation leads to enlarged pores, follicular blockage, and inflammation. NanoActive Sulfur effectively removes surface lipids, softens the epidermis, and dissolves keratin plugs.

●Mechanism:At low concentrations, sulfur exerts a keratoplastic effect, promoting normal keratinization. At higher concentrations, it becomes keratolytic, reacting with cysteine to form cystine and hydrogen sulfide (), which safely disrupts excess keratin and clears clogged pores.

B. Targeted Antibacterial & Antifungal Action

NanoActive Sulfur acts as a potent purifying agent and helps rebalance the skin microbiome.

●Mechanism: Skin bacteria and keratinocytes convert sulfur into pentathionic acid (), a compound highly toxic to fungi and pathogenic bacteria. The keratolytic action further helps detach microorganisms from the stratum corneum.

●Microbiological Efficacy (In Vitro):

○P. aeruginosa: MIC = 1.95 μg/mL | MBC = 1000 μg/mL

○S. aureus: MIC = 125 μg/mL

○E. coli: MIC = 500 μg/mL

C. Powerful Anti-Inflammatory & Soothing Properties

Severe oxidative stress depletes intracellular Glutathione (GSH), triggering inflammatory cascades.

●Mechanism:NanoActive Sulfur supports cellular antioxidant defenses by promoting GSH synthesis.

●Efficacy:Exerts a strong, dose-dependent reduction in the expression of key pro-inflammatory cytokines. Clinical evaluations (ELISA) show that concentrations between 0.1% and 0.4% significantly downregulate the protein expression ofIL-1β,IL-6, and TNF-α.

D. Clinically Proven Acne Treatment

Inin-vivoassessments, formulations containing NanoActive Sulfur demonstrated visible improvement in acne-prone skin profiles. A 60-day application of 0.2% active showed a significant reduction in inflammatory lesions and post-acne erythema, making it an ideal candidate for long-term acne management.

6. RECOMMENDED APPLICATIONS

NanoActive Sulfur is highly versatile and is recommended for the following cosmetic product categories:

  • Acne & Blemish Control: Spot treatments, anti-acne serums, and purifying toners.
  • Sebum Control & Pore Refining: Mattifying lotions, oil-control powders, and deep-cleansing masks.
  • Brightening & Spot-Fading: Post-inflammatory hyperpigmentation (PIH) correctors.
  • Scalp Care: Anti-dandruff shampoos and scalp-soothing serums (seborrheic dermatitis support).
  • Soothing & Repair: Products targeting sensitized, inflamed, or compromised skin barriers.

7. FORMULATION GUIDANCE

  • Suggested Use Level: 0.1% – 5.0% (Depending on target efficacy: low doses for daily maintenance/anti-inflammation; higher doses for targeted spot treatments).
  • Solubility: Amphiphilic nature allows it to be easily added to either the aqueous phase or the final emulsion at room temperature or gently heated conditions.
  • Compatibility: Compatible with a wide range of cosmetic ingredients, including traditional water-based and oil-based systems. Does not cause phase separation.

8. STORAGE, HANDLING & PACKAGING

  • Storage: Store in the original, unopened container at 4°C to 25°C. Protect from direct sunlight and maintain in a dry environment.
  • Shelf Life: 12 months under specified storage conditions.
  • Packaging: Supplied in standard industrial plastic containers.

Disclaimer: The information contained in this document is provided in good faith and is based on our current knowledge and internal testing. Formulators are responsible for ensuring the final cosmetic product’s stability, safety, and regulatory compliance in their respective target markets.

PuriPharm Co. Ltd. | Advanced Active Ingredients

NanoActive MN Advanced Bioactive Ingredient for Skin and Hair Care

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Product Overview

INCI Name

The INCI name is MyristylNicotinate, which is the standardized name in the cosmetic industry.

Product Type

It is an advanced bioactive ingredient specifically designed for skin and hair care products.

Key Feature

It can convert to NAD + in skin cells, improving penetration and reducing irritation compared to regular nicotinic acid.

Features & Applications

Applications

Mechanism of Action

The NAD + pathways and conversion process ofNanoActiveMN

NAD+ Pathways

NAD+ Importance

NAD + is essential for energy generation in mitochondria, lipid synthesis, DNA damage repair, and maintaining mitochondrial function and telomere length.

NAD+ Synthesis Pathways

There are three main pathways: the de novo pathway starting from tryptophan, the Preiss – Handler pathway using nicotinic acid, and the salvage pathway recycling NAD + metabolites.

NAD+ and Skin Health

NAD + is critical for cellular repair, energy metabolism, and combating age – related decline in skin. Its levels decrease by 50% by middle age.

NanoActiveMN Conversion

Efficacy Data

Barrier Repair：

Efficacy data on skin barrier repair

Anti – aging & Antioxidant

1. DPPH Radical Scavenging

The maximum clearance is 6.10% at a concentration of 0.3125%, showing its antioxidant ability.

2. ZO – 1 Protein Expression

At 0.04 mg/mL concentration, there is a 3.38 – fold relative expression of ZO – 1 protein.

3. Synergistic Effects with Retinoic Acid

It reduces irritation, enhances efficacy, and reduces water loss when used with retinoic acid.

Hair Loss Prevention

1. Clinical Study Design

A well – designed study was conducted to evaluate the efficacy ofNanoActiveMN on hair loss prevention.

2. Study Results

There was a significant improvement in hair abundance, density, quality, and thickness, with no adverse effects reported.

3. Mechanism of Action

It converts to NAD + in the scalp, enhancing cellular energy, improving barrier function, stimulating hair follicle cell renewal, and reducing oxidative stress.

Company Introduction

PuriPharmCo. Ltd.

1. Company Background

Specialized in bioactive ingredients, founded by industry experts and has global partnerships with research institutions.

2. Quality & Manufacturing

Strict quality control standards, state – of – the – art manufacturing facilities, and sustainable practices are in place.

3. R&D Capabilities

An expert technical team with PhD – level scientists and advanced laboratory facilities for cosmetic ingredient development.

Core Technologies

Nano Delivery：Advanced nanotechnology for enhanced bioavailability and targeted delivery of active ingredients.

Targeted Action：Allows for targeted action of ingredients at specific skin or hair sites.

Enhanced Penetration：Improves the penetration of ingredients into the skin for better efficacy.

Improved Stability： Ensures the stability of formulations during storage and use.

Formulation Stability

Stability information under different conditions

1. 24 – months Stability at Room Temperature

NanoActiveMN shows good stability in various formulations at room temperature for 24 months.

2. 3 – months Stability at 40℃

It has 3 – months stability at 40℃ in accelerated testing.

3. Minimal Degradation in Complex Formulations

There is minimal degradation in complex cosmetic matrices, ensuring long – term effectiveness.

Storage & Compatibility

Storage Conditions：

Store at 4 – 25℃ in a dry environment, protect from light, and keep the container tightly sealed.

Tested Formulations

It has been tested with various ingredients such as UV filters, emollients, humectants, natural oils, etc.

Ingredient Compatibility

Compatible with a wide range of cosmetic ingredients, including retinoids, antioxidants, emulsifiers, and thickeners.

NanoActive SA Nano-scale Formulations of Health Ingredients

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Skincare Benefits and Market Applications of Salicylic Acid (I)

  • Exfoliates the skin, improves firmness, helps restore youthful elasticity, lightens pigmentation, reduces fine lines, and improves photoaging caused by sun exposure.
  • Mechanism: Salicylic acid causes corneocyte membranes to suddenly lose negative charge, weakening cohesion and promoting desquamation.
  • Representative product: SK-II crystal resurfacing cream.
  • By adding 1.5% salicylic acid to the original Pitera formula and likening its pore- and keratin-refining effect to peeling a shelled egg, the product sparked strong market enthusiasm.

Skincare Benefits and Market Applications of Salicylic Acid (II)

Clears acne, tightens pores, removes blackheads from pores, and provides antibacterial benefits to address oily skin concerns.

Mechanism: Because salicylic acid is lipophilic, it can merge with lipids and penetrate the stratum corneum and deep into pores, helping dissolve aged keratin buildup and improve pore blockage.

Representative product: Vichy oil-control purifying astringent toner.

An ideal conditioning product for problem skin. It further cleanses and repairs the skin, makes pores appear tighter, evens skin tone, and visibly improves shine and blackheads.

Skincare Benefits and Market Applications of Salicylic Acid

The two skincare functions above—exfoliation and oily-skin care—are exactly what the Chinese market needs.

  1. Most Chinese consumers have combination skin and face issues such as shine, enlarged pores, and acne.
  2. The air environment in China still needs improvement. Air pollution can cause thickening of the stratum corneum, dull-looking skin, and the accumulation of bacteria in the horny layer.

The market needs products containing salicylic acid.

Issues with Conventional Salicylic Acid

When pure salicylic acid is used in cosmetics, the following difficulties arise:

  1. It can be irritating and may cause erythema, itching, stinging, or allergic reactions.
  2. It has poor solubility. Salicylic acid is only slightly soluble in water, which limits formulation applications.
  3. Its activity depends on pH. In a low-pH environment, maintaining the free-acid form is important for efficacy.

Solution

In view of the issues above, PuriPharm Co. Ltd. developed NanoActive SA to ensure that salicylic acid can perform its skincare functions more effectively in cosmetics.

NanoActive SA delivers salicylic acid benefits more effectively while reducing irritation and related concerns.

Product Features

Salicylic acid remains in the free-acid form within the nano-carrier, effectively overcoming pH dependence.

Significantly reduces irritation and other adverse reactions associated with salicylic acid.

Completely water-soluble and can also be formulated in oil.

Clear, transparent, convenient, and easy to use.

Unique nanobiological effects such as follicular targeting and a follicular reservoir.

Product Characterization

Laser Particle Size Distribution

Electron Micrograph

NanoActive SA: Evaluation in Oily Skin Care

96% of users were satisfied with products containing NanoActive SA

Comprehensive improvement in oily skin

  • Tightened pores
  • Reduced sebum secretion
  • Fewer comedones

NanoActive SA: Significant Efficacy in Acne Treatment

NanoActive SA: Applications

Enhances skin absorption. When salicylic acid is used with other skincare ingredients, it can improve the skin’s uptake of active ingredients.

Clears pore blockage. This mild acid helps break down blackheads and whiteheads by shedding the outermost layer of dead skin.

Exfoliates and cleanses. Salicylic acid is a keratolytic agent and also provides antibacterial benefits.

Removes dead skin cells and helps prevent acne caused when they mix with dirt and sebum.

Helps resist dryness. Salicylic acid softens keratin and helps defend against dry skin.

NanoActive SA: Use Guidelines

Add during the low-temperature stage.

Recommended dosage: 1–5%.

Avoid ferrous/ferric and other divalent or trivalent metal ions in the formulation system.

NanoActive SA

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1. PRODUCT OVERVIEW

NanoActive SA is an innovative, high-performance delivery system of Salicylic Acid designed specifically for advanced personal care and dermatological formulations. While Salicylic Acid (BHA) is renowned for its exceptional comedolytic and keratolytic properties, its application is often restricted by poor water solubility, crystallization risks, and potential skin irritation at efficacious doses.

PuriPharm utilizes state-of-the-art liposomal nano-encapsulation technology to entrap Salicylic Acid within a biomimetic phospholipid and triglyceride matrix. This proprietary delivery system not only renders the active ingredient highly dispersible in aqueous environments but also ensures a sustained-release profile. The result is a profoundly stabilized, highly bioavailable active that maximizes targeted efficacy while virtually eliminating the stinging and erythema traditionally associated with chemical exfoliants.

2. INCI / CHEMICAL DESCRIPTION

The following composition reflects the typical concentration ranges formulated to ensure optimal encapsulation and stability.

3. KEY FEATURES & ADVANTAGES

  • Superior Water Dispersibility: Seamlessly incorporates into clear aqueous systems, toners, and gels without the need for high concentrations of harsh solvents (e.g., alcohol or excessive glycols).
  • Biomimetic Lipid Matrix: Utilizing phospholipids and natural triglycerides, the carrier system exhibits excellent skin affinity, actively replenishing the stratum corneum while delivering the BHA.
  • Controlled & Sustained Release: Modulates the delivery rate of Salicylic Acid, significantly mitigating acute epidermal shock and reducing potential erythema or stinging.
  • Crystallization Prevention: The nano-matrix physically prevents Salicylic Acid molecules from aggregating and precipitating over time, ensuring long-term shelf stability of the finished cosmetic product.

4. MECHANISM & TECHNOLOGY HIGHLIGHTS

Targeted Follicular Delivery via Nano-vesicles: NanoActive SA functions by enclosing the lipophilic Salicylic Acid core within a phospholipid-based outer shell. When applied to the skin, these sub-micron liposomal carriers exhibit a high affinity for the lipid-rich environment of the pilosebaceous unit. Upon penetrating the pore, the matrix undergoes a gradual degradation process triggered by the skin’s natural physiological environment, releasing the active payload continuously over several hours. This approach ensures maximum keratolytic action exactly where acnegenesis occurs.

5. PHYSICAL & CHEMICAL PROPERTIES

Safety & Purity Specifications:

  • Heavy Metals: Pb < 10 mg/kg | As < 2 mg/kg | Hg < 1 mg/kg | Cd < 5 mg/kg
  • Microbiology: Total Aerobic Count < 100 CFU/g | Yeast & Mold < 10 CFU/g
  • Diethylene Glycol: < 1000 mg/kg

6. SOLUBILITY & COMPATIBILITY

  • Solubility: Readily dispersible in water, glycols, and standard aqueous media.
  • Compatibility: Highly compatible with a wide range of cosmetic excipients, including non-ionic and anionic surfactants, and standard thickeners. Avoid combining with strong alkaline agents that may disrupt the phospholipid encapsulation matrix.

7. PRODUCT BENEFITS & COSMETIC FUNCTIONS

  • Intensive Anti-Acne: Reduces sebum secretion, unplugs impacted pores, and inhibits Cutibacterium acnes proliferation.
  • Gentle Exfoliation: Promotes the shedding of dead keratinocytes, resulting in a smoother, more radiant complexion.
  • Pore Minimizing: Clears cellular debris from pores, visibly reducing their appearance.
  • Scalp Care (Anti-Dandruff): Effective in removing scalp buildup and regulating scalp hyperkeratosis without stripping hair shafts.

8. RECOMMENDED APPLICATIONS

  • Facial Skincare: Anti-acne serums, clarifying toners, exfoliating lotions, spot treatments, and deep-cleansing masks.
  • Cleansers: Foaming gel cleansers and purifying washes.
  • Hair & Scalp Care: Anti-dandruff shampoos and scalp purifying serums.

9. SUGGESTED USE LEVEL & REGULATORY STATUS

  • Suggested Use Level: 0.1% – 20.0%(Applicable for both leave-on and rinse-off formulations).(Note: A 20% addition of NanoActive SA delivers 2.0% of pure Salicylic Acid).
  • Regulatory Restriction: Due to the presence of Salicylic Acid, this product is not to be used in products intended for children under 3 years of age, with the exception of shampoos.

10. FORMULATION GUIDANCE

  • Processing Phase: It is highly recommended to add NanoActive SA during the final cooling phase of the manufacturing process, ideally at temperatures below 45°C (113°F), to preserve the integrity of the liposomal structure.
  • pH Range: Maintain the final formulation pH between 3.5 and 6.0for optimal efficacy and stability.
  • Agitation: Stir gently but thoroughly. Avoid extreme high-shear homogenization post-addition.

11. STORAGE AND HANDLING

  • Storage Conditions: Store in tightly closed original containers in a cool, well-ventilated, and dry place. Optimal storage temperature is between 15°C and 25°C.
  • Light & Temperature: Protect from direct sunlight, prolonged heat exposure, and freezing.
  • Handling: Handle in accordance with good industrial hygiene and safety practices. Refer to the Material Safety Data Sheet (MSDS) for detailed safety instructions.

12. SHELF LIFE

24 months from the date of manufacture when stored properly in unopened original packaging under recommended conditions.

13. PACKAGING INFORMATION

Standard pack sizes available:

  • 1 kg / 5 kg plastic fluorinated jugs
  • 25 kg tightly sealed HDPE drums(Customized packaging available upon request).

CONTACT INFORMATION

PuriPharm Co. Ltd.

Building 6, No. 1366 Hongfeng Road,

Huzhou, Zhejiang, China

Tel:+86-572-2745768  Email:service@puripharm.com

DISCLAIMER:

The information provided in this Product Data Sheet is based on our current knowledge and represents typical characteristics. It is offered in good faith but without warranty. It is the responsibility of the formulator and the user to ensure that the final cosmetic product is safe, stable, and complies with all applicable local regulations and patent laws. PuriPharm Co. Ltd. reserves the right to modify product specifications without prior notice.

Product Data Sheet: NanoActive Retinol

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Manufacturer：PuriPharm Co., Ltd.

Product Name：NanoActive Retinol

Product Category：Stable, Water-soluble, High-absorption Vitamin A

1. Product Description

NanoActive Retinol is a novel preparation developed using a proprietary nano-delivery system. With a particle size ranging between 20-30 nm, this system effectively stabilizes Retinol within nano-carriers. This technology ensures deep skin penetration for maximum efficacy, controlled release, and significantly reduced irritation compared to conventional retinoic acid.

2. Product Identification (INCI)

  • RETINOL (CAS #: 116-31-4)
  • PHOSPHOLIPIDS (CAS #: 123465-35-0)
  • CAPRYLIC/CAPRIC TRIGLYCERIDE (CAS #: 65381-09-1)
  • GLYCERIN (CAS #: 56-81-5)
  • WATER (CAS #: 7732-18-5)

3. Key Benefits & Efficacy

  • Anti-Aging & Anti-Wrinkle: Stimulates collagen and elastin production; increases epidermal thickness and elasticity.
  • Skin Renewal: Enhances cell turnover rate for smoother skin texture.
  • Brightening: Inhibits tyrosinase expression and melanin synthesis to reduce pigmentation and even skin tone.
  • Acne Care: Regulates sebum production and targets acne-causing bacteria (e.g., P. acnes).
  • High Stability & Safety: Significantly improves Retinol stability and minimizes the irritation typically associated with Vitamin A derivatives.
  • Enhanced Bioavailability: Nano-encapsulation ensures high absorption and effective penetration into skin layers.

4. Technical Specifications

4.1. Physical & Chemical Properties

4.2. Chemical Indexes

4.3. Microbiological Indexes

5. Application & Formulation Guidelines

  • Recommended Usage: 0.1% – 1.0%
  • Optimum pH Range: 4.5 – 8.0
  • Application Method: Add to the formula during the final stage of production.
  • Formulation Tips: * Primarily used in night care products.
  • For daytime products, photoprotective agents must be added.
  • Opaque packaging is highly recommended to protect the active ingredient.

6. Storage & Handling

  • Preservatives & Antioxidants: Free from added preservatives and antioxidants.
  • Storage Conditions: Store in original, unopened containers between and . Protect from direct sunlight and moisture.
  • Shelf Life: 12 months from the date of manufacture under recommended conditions.
  • Packaging: Standard plastic containers.

PuriPharm Co., Ltd.Address: 7th Floor, 6E Building, No. 1366 Hongfeng Road, Huzhou, Zhejiang, ChinaTel: 0572-2745768 | Email: service@puripharm.com

PuriActives® PuriVitin™

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1. PRODUCT IDENTITY
Trade Name: PuriActives® PuriVitin™
INCI Name (EU/US): Saccharide Isomerate, Aqua, Citric Acid, Sodium Citrate
CAS No.: 100843-69-4, 7732-18-5, 77-92-9, 68-04-2
Origin: 100% Plant-derived
General Description
PuriVitin™ is a highly effective, 100% plant-derived carbohydrate complex designed to provide deep, long-lasting hydration. Its unique composition is chemically similar to the carbohydrate fraction of the Natural Moisturizing Factor (NMF) found in human skin.
Unlike conventional humectants that can be easily washed off, PuriVitin™ binds physically to the skin’s keratin, creating a moisture reservoir that lasts for up to 72 hours. It is an essential active for formulations targeting instant hydration, barrier repair, and scalp comfort.

2. KEY BENEFITS & CLAIMS
“Magnet-Like” Skin Affinity
●Unique Binding Mechanism: PuriVitin™ binds to the epsilon-amino group of lysine in keratin. This unique binding mechanism ensures the active is not washed off by water, making it ideal for both leave-on and rinse-off products (e.g., shower gels, face cleansers).
●Long-Lasting Hydration: Provides sustained hydration for up to 72 hours, breaking the dry-skin cycle.
Skin Barrier Support
●Strengthens Barrier Function: Improves the skin’s defense against external aggressors (pollution, cold weather, dry air).
●Soothing Effect: Visible reduction in dryness, flakiness, and tightness associated with dehydrated skin.
●Scalp Care: effectively hydrates the scalp, reducing itchiness and improving the overall health of the scalp microbiome environment.
Sensory Profile
●Leaves skin feeling soft, plump, and smooth without stickiness.

3. COMPOSITION DATA

4. TECHNICAL SPECIFICATIONS
Physical & Chemical Properties

Microbiological Standards

5. MECHANISM OF ACTION
PuriVitin™ functions differently from traditional polyols (like glycerin) or macromolecules (like hyaluronic acid).
1.Isomerization: The glucose and fructose from plant kernels are isomerized to create a unique carbohydrate complex.
2.Bio-Mimicry: This complex mimics the composition of carbohydrates found naturally in the Stratum Corneum.
3.Keratin Binding: Upon application, PuriVitin™ forms a permanent bond with the keratinocytes. This bond is so strong that the moisture-locking effect persists until the dead skin cells naturally exfoliate (desquamation), ensuring hydration that outlasts washing.

6. APPLICATIONS & DOSAGE
Recommended Use Level: 1.0 – 5.0%
PuriVitin™ is suitable for a wide range of cosmetic applications:
Skin Care
●Daily Moisturizers: Day and night creams for instant and long-term hydration.
●Serums & Essences: Intensive hydration boosters.
●Anti-Aging: Plumps skin to reduce the appearance of fine lines caused by dehydration.
Rinse-Off Products
●Cleansers & Body Wash: Provides hydration that stays on the skin even after rinsing.
●Hand Soaps: Protects hands from dryness caused by frequent washing.
Hair & Scalp Care
●Shampoos & Conditioners: Hydrates the scalp to prevent flakes and itchiness.
●Hair Masks: Improves moisture retention in the hair shaft.
Body Care
●Body Lotions: For long-lasting comfort on dry areas (elbows, knees, heels).

7.FORMULATION GUIDELINES
●Solubility: Freely soluble in water. Insoluble in oils.
●Incorporation: Can be added to the water phase or at the end of the formulation process (cooling phase).
●Processing Temperature: Stable at temperatures up to 80°C. Can be processed hot or cold.
●pH Stability: Stable across a wide pH range (3.0 – 7.0 recommended for final formulation efficacy).
●Compatibility: Compatible with most cosmetic ingredients, including high concentrations of ethanol and electrolytes.

8. REGULATORY & STORAGE
Storage Conditions
●Store in the original, unopened container.
●Protect from direct sunlight and heat.
●Store at room temperature (15°C – 25°C).
Shelf Life
●36 months from the date of manufacture when stored under recommended conditions.
Packaging
●Standard industrial plastic containers (Drum/Jerry can).
Safety & Regulatory Status
●Vegan: Suitable for vegan formulations.
●Non-GMO: Produced from non-GMO plant sources.
●Preservative Status: Preservative-free (Self-preserving due to high solid content and osmotic pressure).

Disclaimer:
The information provided in this data sheet is based on our current knowledge and experience. It does not relieve the processor from carrying out their own tests and trials. A legally binding assurance of certain properties or suitability for a specific purpose cannot be derived from this data.
Manufacturer:
PuriPharm Co., Ltd.
PuriActives® is a registered trademark of PuriPharm Co., Ltd.

Puripharm is invited to the World Health Expo to showcase the latest nanotechnology applications in the field of comprehensive health

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The first World Health Expo was held at the Wuhan International Expo Center in China on 4th- 10th, April, 2019, which attracted over 4,000 companies from home and abroad and nearly 200,000 people to attend, during which the first Luojia Health Forum along with a number of high-profile and high-quality forums and other parallel ones were held.. As a member company of the Wuhan University Health Industry Alliance, Purui Bio participated in the Expo and presented the latest products at the E2-10 booth. Meanwhile, the company’s founder and Alliance Secretary General Yang Zhengmao participated as a guest speaker in the first Luojia Health Forum, sharing the latest strategic cooperation and new tech breakthroughs of the company with regard to the opportunities and challenges in the field of medicine and health.
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