Product Overview

INCI Name

The INCI name is MyristylNicotinate, which is the standardized name in the cosmetic industry.

Product Type

It is an advanced bioactive ingredient specifically designed for skin and hair care products.

Key Feature

It can convert to NAD + in skin cells, improving penetration and reducing irritation compared to regular nicotinic acid.

Features & Applications

Applications

Mechanism of Action

The NAD + pathways and conversion process ofNanoActiveMN

NAD+ Pathways

NAD+ Importance

NAD + is essential for energy generation in mitochondria, lipid synthesis, DNA damage repair, and maintaining mitochondrial function and telomere length.

NAD+ Synthesis Pathways

There are three main pathways: the de novo pathway starting from tryptophan, the Preiss – Handler pathway using nicotinic acid, and the salvage pathway recycling NAD + metabolites.

NAD+ and Skin Health

NAD + is critical for cellular repair, energy metabolism, and combating age – related decline in skin. Its levels decrease by 50% by middle age.

NanoActiveMN Conversion

Efficacy Data

Barrier Repair：

Efficacy data on skin barrier repair

Anti – aging & Antioxidant

1. DPPH Radical Scavenging

The maximum clearance is 6.10% at a concentration of 0.3125%, showing its antioxidant ability.

2. ZO – 1 Protein Expression

At 0.04 mg/mL concentration, there is a 3.38 – fold relative expression of ZO – 1 protein.

3. Synergistic Effects with Retinoic Acid

It reduces irritation, enhances efficacy, and reduces water loss when used with retinoic acid.

Hair Loss Prevention

1. Clinical Study Design

A well – designed study was conducted to evaluate the efficacy ofNanoActiveMN on hair loss prevention.

2. Study Results

There was a significant improvement in hair abundance, density, quality, and thickness, with no adverse effects reported.

3. Mechanism of Action

It converts to NAD + in the scalp, enhancing cellular energy, improving barrier function, stimulating hair follicle cell renewal, and reducing oxidative stress.

Company Introduction

PuriPharmCo. Ltd.

1. Company Background

Specialized in bioactive ingredients, founded by industry experts and has global partnerships with research institutions.

2. Quality & Manufacturing

Strict quality control standards, state – of – the – art manufacturing facilities, and sustainable practices are in place.

3. R&D Capabilities

An expert technical team with PhD – level scientists and advanced laboratory facilities for cosmetic ingredient development.

Core Technologies

Nano Delivery：Advanced nanotechnology for enhanced bioavailability and targeted delivery of active ingredients.

Targeted Action：Allows for targeted action of ingredients at specific skin or hair sites.

Enhanced Penetration：Improves the penetration of ingredients into the skin for better efficacy.

Improved Stability： Ensures the stability of formulations during storage and use.

Formulation Stability

Stability information under different conditions

1. 24 – months Stability at Room Temperature

NanoActiveMN shows good stability in various formulations at room temperature for 24 months.

2. 3 – months Stability at 40℃

It has 3 – months stability at 40℃ in accelerated testing.

3. Minimal Degradation in Complex Formulations

There is minimal degradation in complex cosmetic matrices, ensuring long – term effectiveness.

Storage & Compatibility

Storage Conditions：

Store at 4 – 25℃ in a dry environment, protect from light, and keep the container tightly sealed.

Tested Formulations

It has been tested with various ingredients such as UV filters, emollients, humectants, natural oils, etc.

Ingredient Compatibility

Compatible with a wide range of cosmetic ingredients, including retinoids, antioxidants, emulsifiers, and thickeners.