Nano phenethyl resorcinol (NanoActive 377)

Nano phenylethyl resorcinol (NanoActive 377) is a new type of phenethyl resorcinol nanoliposome preparation (NanoLiposomal 377).
Product Name: Nano Liposomal 377; BioActive Phenylethyl Resorcinol; NanoActive 377; NanoAcive Phenylethyl Resorcinol; Water-Soluble 377; Fat-Soluble 377 CAS: 85-27-8

Description: Phenylethyl resorcinol is a new high-efficiency skin whitening agent derived from silver pine, which has ultra-strong potential whitening effect: In Vitro Experiments have also proved that it is ten or even hundred times stronger than that of  VC. And it has also been clinically proven to its whitening ability is equivalent to that of hydroquinone. The most important thing among it is that the whitening speed is fast and is favoring to consumers. After more than ten years of continuous studying of the nature and safety of these raw materials, this emerging high-efficiency natural active substance is gradually getting permission from various countries and gradually used in cosmetics. Phenylethyl resorcinol is poorly soluble in water and susceptible to oxidization and discoloration, which limits its application in cosmetics. Nano actives with a particle size of less than 30 nm developed by nano-transmission system (NDS) enable phenylethyl resorcinol to be steadily wrapped in nano-carriers, greatly improving the absorption efficiency and bioavailability. This overcomes the original defects and retains the advantages with a more convenient and wider range of uses.

Phenylethyl resorcinol

Skin care effects

Phenylethyl resorcinol can effectively inhibit melanin synthesis by acting on multiple targets of the melanin synthesis pathway, thereby achieving whitening and brightening effect. Super antioxidant, effectively removes harmful free radicals from the skin, prevents wrinkles caused by aging and free radicals.

SymWhite 377 effectively inhibits the activity of B16 melanoma to form melanin, which is 210 times the kojia acid, and 32 times the arbutin!

 

Tyrosinase inhibitory activity

 

Whitening test–skin model

Clinical trial (unirradiated skin)

Features

  • Added NanoActive 377 to the formula and the color remained the same.
  • NanoActive 377 uses FDA GRAS grade materials for high safety
  • NanoActive E has good heat, pH and shear stability and is easy to use
  • NanoActive 377 greatly improves the stability and bioavailability
  • NanoActive 377 can improve the stability of other active matters in the product and facilitate absorption
  • NanoActive E is 100% water soluble and 100% oil soluble (amphiphilic) for a wide range of application.

 

Applications

  • Inhibits melanin synthesis, reduces pigmentation and whitens the skin
  • Eliminate free radicals and prevent skin aging.
  • Reduce acne marks

The market claims:

  • Originated from the essence of evergreen conifer
  • Is a powerful whitening ingredient
  • Effectively evens skin tone, leaving skin quickly regaining whiteness, clearness, and regaining the bright skin tone of young skin.
  • Lightens dark spots, and the skin becomes bright after use
  • A powerful antioxidant that can be used to fight harmful free radicals that cause skin aging
  • Mild texture, no side effects that irritate the skin
  • Ultra-micro-nano wrapping technology, effective penetration and does not change color

Use: add it at room temperature. Heat it to above 40℃to speed up the dissolution. Recommended dosage: 0.1-5%. The optimum pH range of the system is 3.0-6.5, and the finished product should be protected from direct sunlight (using opaque packaging). It is recommended to add UV absorber to day care products.

Storage: Keep it away from light at a temperature below 25℃.

Posted in Innovative Formulation, product, Whitening and freckle elimination.