PuriActives® SupraFerulix™

Posted on 08/19/202608/19/2026 by L, Y

Ferulic Acid, Reimagined:Meet PuriActives® SupraFerulix™

A supramolecular ferulic acid active for antioxidant, brightening & skin-comfort formulations.

Antioxidant protection is no longer a premium add-on — it is the new baseline.

Skincare has entered the antioxidant era. Consumers increasingly expect daily defense against oxidative stress from UV exposure, urban pollution and the visible signs of photoaging — while also asking for brighter-looking skin, sensitive-skin compatibility and microbiome-friendly care. The challenge for formulators is no longer whether to use an antioxidant, but how to deliver antioxidant performance with greater formulation flexibility and a more elegant skin experience.

01 · THE HERO MOLECULE

Why Ferulic Acid Still Matters

A classic antioxidant with enduring relevance in modern dermocosmetic and prestige skincare.

Ferulic acid · 4-hydroxy-3-methoxycinnamic acid · C10H10O4

Ferulic acid is a well-recognized plant-derived phenolic antioxidant valued for oxidative stress protection, photoaging care and radiance support. It is also known for complementing vitamin C / E antioxidant systems — one reason it remains a familiar ingredient in prestige antioxidant formulas.

Antioxidant profileHelps protect skin from environmental oxidative stress.	Photoaging careSupports skin exposed to UV and environmental stress.
Radiance supportHelps improve the look of dull, tired-looking skin.	Antioxidant synergyKnown for complementing vitamin C / E systems.

02 · THE FORMULATION PARADOX

Powerful, but Demanding

Conventional ferulic acid can make high-performance formulation unnecessarily difficult.

The molecule is compelling. The formulation experience can be less so. Conventional ferulic acid systems may face stability concerns, compatibility limitations, solubility and dispersibility challenges, sensory trade-offs and restricted formulation flexibility. Oxidation-driven color change, formula-environment sensitivity, uneven incorporation, and odor or color impact can all compromise the elegance of a finished product.

The market needs ferulic acid that is easier to formulate — and kinder to skin.

03 · THE PURIPHARM SOLUTION

Not Just an Ingredient. A Smart Active System.

Supramolecular association — designed, not simply mixed.

PuriActives® SupraFerulix™ · supramolecular ferulic acid active

PuriActives® SupraFerulix™ combines ferulic acid with zinc glycinate, xyloglucan and alpha-glucan oligosaccharide in a supramolecular design engineered for formulation flexibility and skin comfort.

FA	Ferulic AcidAntioxidant, anti-photoaging and radiance support — the hero of the system.

ZG	Zinc GlycinateSkin comfort, oil-prone skin support and soothing positioning.

XG	XyloglucanBio-polymer film-forming, barrier support and a hydration-friendly skin feel.

AGO	Alpha-Glucan OligosaccharidePrebiotic-inspired microbiome balance and sensitive-skin care positioning.

04 · SUPRAMOLECULAR DESIGN

A Protective Matrix, Built Around the Active

Four components work together through non-covalent supramolecular interactions.

Rather than treating ferulic acid as a stand-alone molecule, SupraFerulix™ places it within a supportive matrix. The design concept is intended to create a more formulation-friendly environment around the active, while integrating comfort-, barrier- and microbiome-oriented components into the same system.

Non-Covalent AssociationComponents work together through supramolecular interactions, not simple mixing.	A Protective EnvironmentThe supportive matrix positions ferulic acid for more formulation-friendly use.
Comfort-Oriented DesignBuilt for gentle, high-performance daily skincare concepts.	One Synergistic SystemAntioxidant performance is paired with comfort, barrier and microbiome positioning.

05 · FOUR PATHS TO BETTER SKIN

Performance That Goes Beyond Antioxidant Defense

A multi-dimensional skincare story for modern daily-care concepts.

Antioxidant DefenseHelps protect skin from environmental oxidative stress — UV, pollution and daily aggressors.	Barrier SupportA bio-polymer film helps support the moisture barrier and a hydrated skin feel.
Skin ComfortSoothing-oriented design for daily, gentle, high-performance use.	Microbiome BalancePrebiotic-inspired care designed to respect skin’s natural flora.

Xyloglucan supports a smooth, cushiony, hydration-friendly sensory concept.

06 · COMPONENT SPOTLIGHT

Four Roles, One Formula Story

Ferulic Acid is the hero antioxidant: it supports environmental stress defense, radiance and visible photoaging care, while complementing vitamin C / E systems.

Zinc Glycinate brings a mild zinc–amino acid complex into the system, supporting skin-comfort, soothing, sensitive-skin and oil-prone skin positioning.

Xyloglucan is the bio-polymer element. It forms a soft, breathable film, supports moisture retention and barrier function, and contributes to an elegant hydrated skin feel.

Alpha-Glucan Oligosaccharide adds a prebiotic-inspired angle, supporting microbiome-friendly, balance-focused and gentle daily-care concepts.

07 · FORMULATION ADVANTAGES

Designed to Formulate Beautifully

One active system, compatible with a wide range of dosage forms.

Formulation science in practice · illustration from the product presentation

Better CompatibilityImproved formulation compatibility versus conventional ferulic acid systems.	Flexible Across SystemsSuitable for both water-based and emulsion-based formulations.
Elegant Skin FeelA smooth, comfortable sensory profile for prestige positioning.	Clean-Beauty ReadyFits modern clean and minimalist formula concepts.
Sensitive-Skin ConceptsComfort-oriented design for gentle, sensitive-skin positioning.	Dosage-Form FreedomSerums · essences · lotions · creams · masks · ampoules.

08 · READY-TO-DEVELOP CONCEPTS

Seven Product Stories From One Active System

01	Antioxidant Brightening SerumA daily radiance-and-defense hero serum.

02	Urban Defense EssenceLightweight daily shield against pollution stress.

03	Sensitive-Skin Radiance AmpouleGentle glow in an intensive, comfort-first format.

04	Anti-Photoaging CreamDaily defense against visible signs of photoaging.

05	Post-Sun Repair LotionAfter-sun comfort and antioxidant care.

06	Oil-Prone Antioxidant GelLight, balancing antioxidant care for oil-prone skin.

07	Microbiome-Friendly Daily CareEveryday moisturizer supporting skin’s natural balance.

Antioxidant brightening serum · concept visual

09 · WHY UPGRADE

Conventional Ferulic Acid vs. SupraFerulix™

Dimension	Conventional Ferulic Acid	PuriActives® SupraFerulix™
System design	Single antioxidant molecule	Supramolecular active system
Formulation	Limited flexibility; stability and color-change concerns	Formulation-friendly design for modern systems
Care concept	Active-only approach	Antioxidant + comfort + barrier + microbiome concept
Positioning	Classic antioxidant	Modern, skin-comfort-oriented active system

SupraFerulix™ advantages reflect design intent; detailed performance should be confirmed against PuriPharm technical data.

10 · CLAIMS & SUPPORT

A Communication Platform Built for Cosmetic Formulation

Claim DirectionHelps protect skin from oxidative stress.	Claim DirectionSupports brighter-looking skin.
Claim DirectionHelps improve dull-looking complexion.	Claim DirectionSupports skin comfort.
Claim DirectionMicrobiome-friendly antioxidant system.	Claim DirectionDesigned for sensitive-skin-compatible antioxidant formulations.

Final claims should be validated against the regulatory requirements of each target market.

Documentation and technical support accompany the product.

Every batch is backed by complete documentation: TDS, COA, SDS, product specification, formulation guidance, regulatory support for target markets and customized technical communication on request.

Ferulic acid, reimagined as a modern supramolecular active system. PuriActives® SupraFerulix™ turns a classic antioxidant into a high-performance, skin-comfort-oriented system for antioxidant, brightening and gentle daily-care formulations.

ANTIOXIDANT DEFENSE · SKIN COMFORT · FORMULATION FREEDOM

PuriPharm Co., Ltd.

www.puriactives.comservice@puripharm.com · +86-572-2745768Building 6, No. 1366 Hongfeng Road, Huzhou, Zhejiang, China

For cosmetic formulation use only. No drug claims intended.

PuriVitin® S100 The Moisture Magnet

Posted on 08/18/202608/18/2026 by L, Y

SACCHARIDE ISOMERATE · MOISTURE MAGNET

72-Hour Long-Lasting Deep Hydration · High-Assay Powder · Preservative-Free · Skin-Identical Technology

PuriPharm Co. Ltd. · Huzhou, China · www.puriactives.com

CONTENTS

Agenda

PRODUCT PRESENTATION

01 Insight The unmet need in skin hydration

02 Science Magnet-like binding mechanism & proven efficacy

03 Advantage Why the powder format

04 Application & Specification Formulation guide · Technical specs · Quality assurance

CHAPTER 01 · INSIGHT Hydration, the First Principle of Skincare Among all skincare claims, hydration is the most fundamental — and the least perfectly solved. Water must not only be delivered, but retained.

01 · INSIGHT

Why Traditional Humectants Never Truly Stay

① Glycerin & Polyols Passive hygroscopicity depends on ambient humidity and drops sharply in dry air; higher doses turn sticky while water still escapes fast.

② Hyaluronic Acid High-MW molecules sit on the surface forming a film rather than penetrating the stratum corneum — largely removed by a single wash.

③ Ordinary Sugar Humectants Lacking skin affinity, they merely rest on the surface; in rinse-off formats they are flushed away almost completely.

The market needs not more water — but water that stays.HYDRATION THAT STAYS, NOT JUST HYDRATION

Sources: Flychem, Saccharide Isomerate Formulation Guide; public technical literature

PuriActives® PuriVitin S100 · The Moisture Magnet

A Small Sugar, Skin-Identical by Nature

INCI Name：Saccharide Isomerate

CAS No.：100843-69-4

Origin：Saccharide complex obtained by isomerization of plant-derived carbohydrates

Composition：A blend of mono- and disaccharides, similar in composition to the sugars of skin NMF

Mol. Weight：120 – 400 Da

Appearance：Pale yellow to white powder, characteristic odor

SKIN-IDENTICAL：Highly similar to the sugar complex of the skin’s own NMF — not a foreigner, but one of our own.

Skin identity means inherent biocompatibility and mildness — the structural basis of lasting hydration.

Sources: CIR Safety Assessment of Saccharide Humectants; PuriPharm PuriVitin S100 Product Specification

PuriActives® PuriVitin S100 · The Moisture Magnet

CHAPTER 02 · SCIENCE It Clings to Skin, Like a Magnet A unique binding mechanism turns hydration from a surface act into deep retention — bind, retain, stay: a three-step loop of lasting moisturization.

02 · MECHANISM

Magnet-Like Binding: A Three-Step Loop

01 · Magnetic Binding · BIND The sugar complex forms hydrogen bonds with the ε-amino groups of lysine in keratin, anchoring itself into skin rather than sitting on it.

02 · Water Reservoir · RESERVOIR Bound sugars continuously attract and lock in water, building a lasting moisture reservoir within the stratum corneum — instant and deep.

03 · Long-Term Stay · STAY The bond cannot be washed off; it is removed only by natural desquamation, keeping skin hydrated for 72 hours and beyond.

CANNOT BE WASHED OFF — REMOVED ONLY BY NATURAL DESQUAMATION

02 · EFFICACY

72 Hours of Deep, Long-Lasting Hydration

72h LONG-LASTING DEEP HYDRATION A single application creates a moisture reservoir for instant, deep hydration that persists for 72 hours — even through daily cleansing routines.

3h：Instant boost on extra-dry areas Perceptible hydration of the driest facial zones within 3 hours

28d：True hydration across all facial areas Daily use steadily improves hydration of every facial zone over 28 days

+275%：Skin moisture increase after one use In-vivo body-lotion study: +275% skin moisture after a single application

75%：Softer skin, no tightness — self-assessed 0.2–0.5% shower gel, skin still hydrated after 7 days of frequent washing

Beyond Hydration: Barrier Repair & Soothing

50%+Smoother Clinical scoring shows over 50% improvement in smoothness and softness after only 2 weeks, with flakiness and itch reduced by more than half.

2×：Faster barrier recovery vs control In-vivo study: more than 2× the barrier repair rate, 24 hours ahead of a leading benchmark

2×：Redness relief 2× the benchmark Significant soothing of dryness-induced redness and sensitivity — ideal for sensitive-skin formulas

24h：24-hour soothing for body skin Relieves dryness from frequent washing, sanitizers and daily cleansing stress

Strengthening the skin’s own defense, cutting water loss at the source — this is what moisture retention truly means.

Activating Skin’s Own Hydration Program

PuriVitinS100

Filaggrin ↑ NMF SYNTHESIS Elevates NMF levels, strengthening the water-holding power of the stratum corneum

Hyaluronan Synthase-3 (HAS-3) ↑ ENDOGENOUS HA Stimulates endogenous hyaluronic acid production — moisture from within

Loricrin ↑ BARRIER STRUCTURE Reinforces the cornified envelope for a more complete barrier architecture

Acid Sphingomyelinase (ASM) ↑ CERAMIDES Boosts ceramide synthesis, replenishing intercellular lipids to curb water loss

More than external hydration — it awakens the skin’s own moisture system, inside and out.

02 · COMPARISON

A Fundamental Difference from Classic Humectants

Dimension	PuriVitin S100	Glycerin	Hyaluronic Acid
Mechanism	Hydrogen-bonded to keratin — becomes part of the skin	Surface hygroscopicity, humidity-dependent	Surface film-forming occlusion
Wash Resistance	Cannot be washed off; removed only by natural desquamation	Easily rinsed away	Largely removed by washing
Longevity	72-hour continuous deep hydration	Hours only; needs reapplication	Short-term surface hydration
Barrier Care	Upregulates barrier genes, reduces TEWL	Indirect, limited	Mainly occlusive film

Glycerin and hyaluronic acid are water passing through; the Moisture Magnet is water that moves in.

Sources: CIR Safety Assessment; Flychem Formulation Guide

PuriActives® PuriVitin S100 · The Moisture Magnet

CHAPTER 03 · ADVANTAGE Why the Powder Format? The same magnet, in its purest form — higher assay, lighter load, and benefits that run from plant to formula.

03 · POWDER ADVANTAGES

S100 Powder: Five Core Advantages

01 · High Assay Dry powder with moisture ≤10% — actives far above a standard 50% aqueous grade, so less goes further

02 · Easy Logistics No water weight: far lighter and smaller shipments at ambient 4–25°C storage — lower freight and warehousing costs

03 · Easy Handling Precise weighing and dosing; fits aqueous, emulsion, anhydrous and powder formats alike

04 · Preservative-Free Low water activity naturally suppresses microbial growth — no preservatives needed in the raw material

05 · Proven Safety CIR safety assessment: low toxicological risk, non-sensitizing — decades of safe use worldwide

≤10% MOISTURE CONTENT · 36 SHELF LIFE (MONTHS) · 0 PRESERVATIVES ADDED

03 · POWDER VS LIQUID

Powder Grade vs Standard Aqueous Grade

Dimension	PuriVitin S100 Powder	Standard 50% Aqueous Grade
Active Content	High (moisture ≤10%)	Approx. 50%
Recommended Dose	0.2 – 1.0% (leave-on)	1 – 3%
Preservation	No preservatives required	Water-based: microbial control needed
Storage & Shipping	Ambient, lightweight, compact	Roughly 2× weight and volume
Microbial Risk	Low water activity, low risk	Relatively higher
Suitable Systems	Aqueous / emulsion / anhydrous / powder	Aqueous / emulsion

Note: Aqueous-grade figures are general references from public technical literature of the same INCI; please refer to each supplier’s TDS. Dosage conversion is based on active content.

Sources: Flychem, Saccharide Isomerate grade comparison guide; PuriPharm Product Specification

PuriActives® PuriVitin S100 · The Moisture Magnet

04 · APPLICATION

Formulation Guide

Solubility Readily water-soluble; add to the water phase — pre-dispersing in a little water avoids clumping

Process Suitable for cold and hot processing; keep heated stages below 60°C

pH Range Stable across a wide pH window (ref. 4–10), including high-pH soap bases

Dosage Leave-on 0.2 – 1.0%; rinse-off 0.2 – 0.5% (powder grade, active-adjusted)

Compatibility Synergistic with glycerin, hyaluronic acid, ceramides and niacinamide; works as a hydration booster for glycerin

APPLICATIONS Head-to-Toe Formats• Facial serums · ampoules · toners • Creams · lotions · eye care • Masks · lyophilized powders · anhydrous • Body lotion · hand cream · after-sun • Shampoo · conditioner · scalp care • Cleansers · shower gels · bar soaps

04 · SPECIFICATION

Technical Quality Standard

Category	Item	Specification	Unit
Physico-chemical	Color	Pale yellow to white	—
	Odor	Characteristic	—
	Aspect	Powder	—
	Moisture	≤ 10	%
	Refractive index (50% aq., 25°C)	1.42 – 1.43	—
Safety & Micro	Heavy Metals	≤ 20	ppm
	Aerobic Plate Count	≤ 1000	CFU/g
	Escherichia coli	Negative	—
	Salmonella	Negative	—
Storage & Pack	Shelf Time	36	months
	Storage Temperature	4 – 25	°C
	Storage & Packaging	Cool, dry, sealed, protected from light; plastic container	—

Source: PuriPharm Co. Ltd., PuriActives® PuriVitin S100 Product Specification (revision date: 2024-12-02), approved by the Manager of Quality Control.

PuriActives® PuriVitin S100 · The Moisture Magnet

04 · QUALITY & COMPLIANCE

Global Compliance, Traceable Quality

Rigorous Quality Control Batch release testing with internal heavy-metal and microbial limits stricter than industry norms; COA supplied with every lot

Compliant in Major Global Markets INCI listed; compliant with EU Regulation (EC) No 1223/2009; hundreds of products reported in the US FDA VCRP; the same INCI holds quasi-drug additive status in Japan

Authoritative Safety Endorsement US CIR safety assessment: low toxicological risk, non-sensitizing; leave-on use recorded up to 2.8%, with decades of safe application

REFERENCES References & Data Sources1. CIR. Safety Assessment of Saccharide Humectants as Used in Cosmetics. 2021 2. DSM-Firmenich. PENTAVITIN® official product information (same INCI) 3. Happi. DSM Pentavitin Provides Deep Hydration for Skin and Hair Care. 2011 4. DSM. Rinse-off in-vivo efficacy studies. Personal Care, 2021 5. Flychem. Saccharide Isomerate formulation guide 6. PuriPharm Co. Ltd. PuriVitin S100 Product Specification, 2024 Note: Items 2–5 are public studies of the same INCI (Saccharide Isomerate). Efficacy claims should be validated in the final formulation.

PURIACTIVES® BY PURIPHARM Every gram of your formula, holding on to water. HYDRATION THAT STAYS — PURIVITIN S100 PuriPharm Co. Ltd. No. 1366 Hongfeng Road, Huzhou, Zhejiang, China Tel +86-572-2745768 · service@puripharm.com www.puriactives.com This document is provided in good faith for formulation reference only; suitability testing and regulatory compliance remain the user’s responsibility.

PuriActives® Ceramide E

Posted on 08/17/202608/17/2026 by L, Y

PuriActives® Ceramide E

The Advanced Pseudo-Ceramide Solution for Superior Skin Barrier Repair

PuriPharm Co. Ltd.

The Ceramide Challenge

Understanding the vital role of ceramides and the complex limitations of natural extraction in modern cosmetics.

The “Brick and Mortar” Model

The Epidermal Barrier
Ceramides account for over 50% of the stratum corneum lipids, acting as the essential ‘mortar’ holding the cellular ‘bricks’ together.

Moisture Retention
They uniquely form a structured lamellar network that powerfully binds water, actively preventing transepidermal water loss (TEWL).

Depletion Factors
Age, harsh chemicals, and environmental stressors rapidly deplete natural ceramides, inevitably leading to dryness, flaking, and irritation.

Natural Ceramide Limits

Natural ceramides are incredibly difficult and expensive to extract from plant or animal sources.

They exhibit notoriously poor solubility in both water and standard cosmetic oils.

Extremely high melting points (often over 90°C) make them challenging to formulate into stable emulsions.

Consequently, cosmetic formulators are often forced to use low, ineffective concentrations to prevent crystallization in the final product.

Introducing Ceramide E

A scientifically engineered, highly stable synthetic pseudo-ceramide developed by PuriPharm.

What is Ceramide E?

Scientific Profile
INCI: Cetyl-PG Hydroxyethyl Palmitamide.

It is a meticulously lab-created synthetic pseudo-ceramide designed to perfectly mimic the complex molecular structure and barrier function of natural epidermal sphingolipids.

The PuriActives® Advantage
It completely overcomes the formulation hurdles of natural ceramides. Ceramide E delivers identical barrier repair, profound hydration, and anti-inflammatory properties while remaining highly stable, safe, and cost-effective for modern skincare.

Replicating Nature

50% of Stratum Corneum Lipids

Biomimetic Structural Integrity

PuriActives® Ceramide E perfectly integrates into the skin’s natural lipid matrix. It acts as an identical substitute for the natural ceramides that naturally comprise half of your skin’s protective outer layer, ensuring long-lasting defense against environmental aggressors.

Mechanism of Action

Restoring the Lamellar Network

Ceramide E easily penetrates the upper layers of the epidermis, integrating directly into the compromised lipid matrix. It rapidly forms highly organized lamellar structures, effectively replacing lost intercellular “mortar”. This actively restores the structural integrity of the stratum corneum, locking in essential moisture while blocking external irritants.

Clinical Efficacies

Proven, measurable results in long-term skin hydration, structural protection, and barrier repair.

Core Skincare Benefits

Deep Hydration:
Massively enhances the skin’s capacity to retain moisture at a cellular level, dramatically improving overall elasticity, softness, and suppleness over continuous use.

Barrier Repair:
Actively replenishes the crucial lipid layer, effectively sealing microscopic epidermal cracks to stop transepidermal water loss (TEWL).

Soothing & Anti-Irritant:
Significantly reduces redness, flaking, and severe inflammation, making it highly recommended for sensitive, reactive, or eczema-prone skin types.

Anti-Aging Support:
Reinforces skin firmness and visibly minimizes the appearance of fine lines and wrinkles by maintaining optimal structural hydration and tissue resilience.

TEWL Reduction

Clinical applications demonstrate a dose-dependent, significant reduction in Transepidermal Water Loss (TEWL) compared to standard humectants, indicating a vastly fortified skin barrier.

24-Hour Hydration Trend

Unlike traditional humectants offering temporary relief, Ceramide E structurally locks in moisture, maintaining a significantly higher skin hydration index across a full 24-hour cycle.

Targeted Skin Conditions

Dry & Winter Skin
Eliminates flakiness and severe dryness by artificially rebuilding the compromised moisture barrier against harsh elements.

Sensitive & Atopic
Provides exceptional soothing relief for irritation, redness, and biologically compromised skin conditions like eczema.

Mature & Aging Skin
Combats the natural age-related decline of ceramide production, effectively restoring youthful firmness and tissue density.

Formulation Superiority

Formulators highly prefer PuriActives® Ceramide E as it completely bypasses the instability and crystallization risks of natural ceramides.

As a high-purity synthetic pseudo-ceramide, it offers exceptional batch consistency, prolonged shelf life, and effortless integration into complex cosmetic emulsions without degrading other actives.

Formulation & Applications

Technical guidelines and product versatility for cosmetic integration.

Versatile Applications

Facial Care
Essential for intensive barrier repair creams, high-end anti-aging serums, toners, and sensitive skin daily moisturizers.

Body Care
Highly effective in therapeutic body lotions, eczema-relief ointments, foot repair treatments, and winter care formulations.

Scalp & Hair
Excellent for anti-dandruff treatments, scalp soothing tonics, and deep conditioning hair masks to repair cuticle damage.

The Future of Barrier Care

“Synthetic pseudo-ceramides represent a critical breakthrough, delivering the profound barrier-repairing power of natural sphingolipids with unprecedented formulation stability.”

— Dermatological Research Perspectives