PuriActives® 7-DHC
Vitamin D3 Precursor for Skin Resilience & Renewal
INNOVATION IN SKIN SCIENCE
PURIPHARM BRAND ARCHITECTURE
7-DHC: THE RESILIENCE ANCHOR
ADDRESSING MODERN SKIN STRESS
BEYOND BASIC MOISTURE
MARKET DEMAND FOR RESILIENCE
WHAT IS 7-DEHYDROCHOLESTEROL?
PURIACTIVES® 7-DHC BENEFITS
THE BIOLOGICAL PATHWAY
CELLULAR STRESS RESILIENCE
POST-SUN COMFORT
BIOLOGICAL BALANCE & RENEWAL
SUBSTANTIATION SUMMARY
HSP MRNA UPREGULATION
PILOT STUDY RESULTS
CLAIM DIRECTION GUIDE
TECHNICAL GUIDANCE
PRODUCT CONCEPT PROTOTYPES
COMPLIANCE & SAFETY
THE MARKETING EDGE
NanoActive® 7-DHC THE SKIN-NATIVE PROVITAMIN D PLATFORM
Retinal (Retinaldehyde) Market Outlook & Strategic Analysis Report
I. Background:
The “EU Vitamin A Restriction” Shaking the Industry
The formal implementation of Regulation (EU) 2024/996 marks a pivotal regulatory turning point for Vitamin A derivatives in the skincare industry.
1. Key Regulatory Highlights
- Concentration Thresholds: From November 1, 2025, new face and leave-on products must not exceed 0.3% Retinol Equivalent (RE); body lotions are limited to 0.05% RE.
- Grace Period: Non-compliant products already on the market must be withdrawn by May 1, 2027.
- Mandatory Labeling: Products must include a warning: “Contains Vitamin A. Consider your daily intake before use.”
2. Industry Ripple Effects
This regulation forces a paradigm shift from “High Concentration” to “High Efficiency.” Retinal (Retinaldehyde), the direct precursor to Retinoic Acid, has emerged as the premier alternative to Retinol, offering superior performance within the new legal limits.
II. Core Value:
Why Retinal is the “Optimal Solution”
Under the 0.3% concentration cap, Retinal provides a much higher “performance ceiling” compared to Retinol.
- Conversion Efficiency: Retinal requires only one conversion step to become Retinoic Acid (the active form), whereas Retinol requires two. Research indicates Retinal’s bio-activity is approximately 10-11 times more efficient than Retinol.
- Compliance Advantage: At the 0.3% EU limit, Retinal can deliver anti-aging results comparable to unregulated high-concentration Retinol (1.0%+) products of the past.
- Antibacterial Benefits: Unlike Retinol, Retinal possesses natural antimicrobial activity, making it a unique solution for the “adult acne & anti-aging” dual-segment.
III. Technical Strategy:
Advanced Delivery & Synergistic Formulas
To overcome Retinal’s inherent instability, the following next-generation combinations are recommended:
1. Retinal + Silybin (Phyto-Retinol Strategy):
- Silybin is highlighted as the premier plant-based Retinol alternative. It promotes collagen regeneration via “Retinoid-like” pathways without the irritation.
- Its potent anti-inflammatory properties significantly down-regulate pro-inflammatory cytokines, mitigating the potential irritation often associated with Retinal.
2. Retinal + Hexylresorcinol (Multi-Target Aging):
- Hexylresorcinol inhibits melanin synthesis while reinforcing the dermal support structure.
- This synergy achieves a “1+1>2” effect for intensive wrinkle reduction and skin tone brightening.
IV. Core Competitive Advantages of PuriPharm
As a leader in Nano-Delivery Systems (NDS), PuriPharm is uniquely positioned to solve the stability and penetration challenges of Retinal:
1. Pharmaceutical-Grade Nano-Encapsulation (NanoActive®)
- Solving Stability Issues: Retinal is extremely sensitive to light and oxygen. PuriPharm’s Nano-Liposome technology isolates the active from environmental factors, ensuring long-term potency.
- Enhanced Skin Penetration: With particle sizes typically below 30nm, NanoActive® RAL (Retinal) penetrates the skin barrier more effectively than traditional formulations, reaching the deeper dermis.
- Reduced Irritation (De-noising): Controlled release technology ensures a steady delivery of actives, minimizing the “Retinoid reaction” (redness and peeling).
2. Comprehensive Synergistic Ingredient Portfolio
- PuriPharm provides a complete suite of nano-encapsulated actives, including NanoActive® RAL, NanoActive® Silybin, and NanoActive® Hexylresorcinol.
- Universal Nano-Compatibility allows formulators to combine these “Triple Threat” ingredients seamlessly, ensuring physical stability and a premium, non-greasy skin feel.
3. Professional R&D & Data Support
● Backed by a founding team with deep pharmaceutical backgrounds, PuriPharm provides robust in-vitro and clinical efficacy data. This assists global brands in justifying their claims and navigating strict EU labeling requirements.
V. Strategic Opportunities for the International Market
- “Concentration-to-Efficiency” Rebranding: Help brands leverage 0.3% Retinal Nano-products to outperform 1.0% Retinol competitors in efficacy.
- Global Compliance Transition: Provide ready-to-use, EU-compliant ingredient solutions and stability dossiers for brands looking to enter or stay in the European market.
- Custom NDS Development: Utilize the NDS platform to create exclusive “Retinal + X” nano-complexes, building a proprietary technical moat for the brand.
VI. Conclusion
The EU Vitamin A restriction is not an end, but the beginning of the “Era of Scientific Anti-Aging.” By utilizing PuriPharm’s Nano-Delivery Systems to master the stability and delivery of Retinal, brands can achieve market dominance in the post-retinol landscape.
Retinal (Retinaldehyde) Market Outlook & Strategic Analysis Report
I. Background:
The “EU Vitamin A Restriction” Shaking the Industry
The formal implementation of Regulation (EU) 2024/996 marks a pivotal regulatory turning point for Vitamin A derivatives in the skincare industry.
1. Key Regulatory Highlights
- Concentration Thresholds: From November 1, 2025, new face and leave-on products must not exceed 0.3% Retinol Equivalent (RE); body lotions are limited to 0.05% RE.
- Grace Period: Non-compliant products already on the market must be withdrawn by May 1, 2027.
- Mandatory Labeling: Products must include a warning: “Contains Vitamin A. Consider your daily intake before use.”
2. Industry Ripple Effects
This regulation forces a paradigm shift from “High Concentration” to “High Efficiency.” Retinal (Retinaldehyde), the direct precursor to Retinoic Acid, has emerged as the premier alternative to Retinol, offering superior performance within the new legal limits.
II. Core Value:
Why Retinal is the “Optimal Solution”
Under the 0.3% concentration cap, Retinal provides a much higher “performance ceiling” compared to Retinol.
- Conversion Efficiency: Retinal requires only one conversion step to become Retinoic Acid (the active form), whereas Retinol requires two. Research indicates Retinal’s bio-activity is approximately 10-11 times more efficient than Retinol.
- Compliance Advantage: At the 0.3% EU limit, Retinal can deliver anti-aging results comparable to unregulated high-concentration Retinol (1.0%+) products of the past.
- Antibacterial Benefits: Unlike Retinol, Retinal possesses natural antimicrobial activity, making it a unique solution for the “adult acne & anti-aging” dual-segment.
III. Technical Strategy:
Advanced Delivery & Synergistic Formulas
To overcome Retinal’s inherent instability, the following next-generation combinations are recommended:
1. Retinal + Silybin (Phyto-Retinol Strategy):
- Silybin is highlighted as the premier plant-based Retinol alternative. It promotes collagen regeneration via “Retinoid-like” pathways without the irritation.
- Its potent anti-inflammatory properties significantly down-regulate pro-inflammatory cytokines, mitigating the potential irritation often associated with Retinal.
2. Retinal + Hexylresorcinol (Multi-Target Aging):
- Hexylresorcinol inhibits melanin synthesis while reinforcing the dermal support structure.
- This synergy achieves a “1+1>2” effect for intensive wrinkle reduction and skin tone brightening.
IV. Core Competitive Advantages of PuriPharm
As a leader in Nano-Delivery Systems (NDS), PuriPharm is uniquely positioned to solve the stability and penetration challenges of Retinal:
1. Pharmaceutical-Grade Nano-Encapsulation (NanoActive®)
- Solving Stability Issues: Retinal is extremely sensitive to light and oxygen. PuriPharm’s Nano-Liposome technology isolates the active from environmental factors, ensuring long-term potency.
- Enhanced Skin Penetration: With particle sizes typically below 30nm, NanoActive® RAL (Retinal) penetrates the skin barrier more effectively than traditional formulations, reaching the deeper dermis.
- Reduced Irritation (De-noising): Controlled release technology ensures a steady delivery of actives, minimizing the “Retinoid reaction” (redness and peeling).
2. Comprehensive Synergistic Ingredient Portfolio
PuriPharm provides a complete suite of nano-encapsulated actives, including NanoActive® RAL, NanoActive® Silybin, and NanoActive® Hexylresorcinol.
Universal Nano-Compatibility allows formulators to combine these “Triple Threat” ingredients seamlessly, ensuring physical stability and a premium, non-greasy skin feel.
3. Professional R&D & Data Support
- Backed by a founding team with deep pharmaceutical backgrounds, PuriPharm provides robust in-vitro and clinical efficacy data. This assists global brands in justifying their claims and navigating strict EU labeling requirements.
V. Strategic Opportunities for the International Market
- Concentration-to-Efficiency Rebranding: Help brands leverage 0.3% Retinal Nano-products to outperform 1.0% Retinol competitors in efficacy.
- Global Compliance Transition: Provide ready-to-use, EU-compliant ingredient solutions and stability dossiers for brands looking to enter or stay in the European market.
- Custom NDS Development: Utilize the NDS platform to create exclusive “Retinal + X” nano-complexes, building a proprietary technical moat for the brand.
VI. Conclusion
The EU Vitamin A restriction is not an end, but the beginning of the “Era of Scientific Anti-Aging.” By utilizing PuriPharm’s Nano-Delivery Systems to master the stability and delivery of Retinal, brands can achieve market dominance in the post-retinol landscape.
NanoActive Oridonin(Liposomal Oridonin)
Stable Water-Soluble Oridonin
Product Overview
NanoActive Oridonin represents a groundbreaking advancement in cosmetic active ingredients, combining the potent bioactive properties of oridonin with state-of-the-art liposomal delivery technology. As part of PuriPharm’s prestigious NanoActive® series, this innovative ingredient addresses multiple signs of skin aging through a sophisticated multi-target approach, making it an exceptional choice for premium skincare formulations targeting skin tone improvement and overall skin revitalization.
Oridonin, a bioactive diterpenoid compound naturally occurring in Rabdosia rubescens, has been extensively studied for its remarkable biological activities. However, its practical application in cosmetic formulations has been historically limited due to poor water solubility and stability challenges. PuriPharm has successfully overcome these obstacles through advanced liposomal encapsulation technology, creating a stable, water-soluble form that maintains full bioactivity while ensuring optimal skin penetration and sustained release.
Product Identification
Key Benefits
NanoActive Oridonin delivers comprehensive skin tone enhancement through its unique ability to address three fundamental visible skin pigments that serve as true markers of skin aging. This triple-action mechanism sets it apart from conventional brightening ingredients that typically target only melanin production.
Melanin Reduction
NanoActive Oridonin effectively inhibits melanogenesis through multiple pathways, reducing the appearance of hyperpigmentation, age spots, and uneven skin tone. The liposomal delivery system ensures that the active compound reaches melanocytes in the basal layer of the epidermis, where it modulates tyrosinase activity and interrupts the melanin synthesis cascade. Clinical observations have demonstrated significant improvements in skin luminosity and reduction in pigmented lesions with consistent application.
Hemoglobin Modulation
Unlike most brightening agents, NanoActive Oridonin also addresses vascular-related skin discoloration by modulating hemoglobin visibility. This is particularly beneficial for reducing the appearance of facial redness, telangiectasia, and post-inflammatory erythema. The compound’s anti-inflammatory properties help calm irritated skin while strengthening capillary walls, resulting in a more uniform and balanced complexion. This dual-action approach to both melanin and hemoglobin makes it exceptionally effective for individuals with complex skin tone concerns.
Collagen Synthesis Enhancement
Beyond pigment correction, NanoActive Oridonin actively promotes collagen synthesis in dermal fibroblasts. This pro-collagen activity helps restore skin firmness and elasticity while reducing the appearance of fine lines and wrinkles. The compound stimulates fibroblast proliferation and upregulates type I collagen production, contributing to overall skin rejuvenation. This comprehensive approach ensures that skin not only appears more even-toned but also demonstrates improved texture and youthful resilience.
Mechanism of Action
The efficacy of NanoActive Oridonin stems from its sophisticated multi-target mechanism that addresses skin aging at the cellular level. Understanding these mechanisms is essential for formulators seeking to maximize the ingredient’s potential in their product development.
Upon application, the liposomal carriers penetrate the stratum corneum through intercellular lipid pathways, delivering the encapsulated oridonin to targeted skin layers. The phospholipid bilayer structure of the liposomes mimics natural cell membranes, facilitating fusion with keratinocyte membranes and enabling efficient intracellular delivery. This targeted delivery system significantly enhances bioavailability compared to conventional formulations, ensuring that a higher percentage of the active compound reaches its intended site of action.
Once released, oridonin interacts with multiple cellular signaling pathways. It modulates the expression of melanogenesis-related enzymes, including tyrosinase, TRP-1, and TRP-2, through downregulation of MITF (microphthalmia-associated transcription factor). Simultaneously, it activates TGF-beta signaling pathways that promote collagen synthesis while inhibiting MMP enzymes responsible for collagen degradation. This coordinated action results in visible improvements in skin tone, texture, and overall appearance.
Technical Advantages
The liposomal encapsulation technology employed in NanoActive Oridonin represents a significant advancement in cosmetic ingredient delivery systems. This sophisticated approach addresses the inherent challenges associated with oridonin while unlocking its full therapeutic potential for skincare applications.
- Enhanced Stability: The liposomal encapsulation protects oridonin from oxidation, photodegradation, and chemical degradation, ensuring consistent potency throughout the product shelf life. This stability enhancement allows formulators to create products with extended shelf stability without compromising efficacy.
- Superior Water Solubility: The transformation from a poorly water-soluble compound to a readily dispersible liposomal suspension enables seamless integration into aqueous formulations, expanding formulation possibilities for serums, essences, and lightweight moisturizers.
- Optimized Skin Penetration: Liposomal carriers enhance transdermal delivery by facilitating passage through the stratum corneum and promoting accumulation in the epidermis and upper dermis, where the active compound can exert its beneficial effects on melanocytes and fibroblasts.
- Sustained Release Profile: The controlled release mechanism ensures prolonged activity at the target site, reducing the frequency of application needed to achieve optimal results while minimizing potential irritation from concentrated exposure.
- Biocompatible Delivery System: The phospholipid-based liposomes are biocompatible and well-tolerated by all skin types, including sensitive and compromised skin barriers, making NanoActive Oridonin suitable for a wide range of cosmetic applications.
Recommended Applications
NanoActive Oridonin’s versatile profile makes it an ideal active ingredient for various premium skincare formulations. Its water-soluble nature and excellent stability allow for flexible incorporation into diverse product formats, enabling formulators to create innovative solutions for comprehensive skin tone correction and anti-aging benefits.
- Brightening and whitening serums targeting hyperpigmentation and age spots
- Anti-aging creams and lotions with comprehensive rejuvenation benefits
- Skin tone evening treatments for redness-prone and uneven complexions
- Post-procedure recovery formulations designed to calm and restore skin
- Premium facial essences and treatment concentrates for intensive care
- Multi-functional day and night creams with tone-correcting properties
About PuriPharm Co. Ltd.
PuriPharm Co. Ltd. is a leading innovator in the development and manufacturing of high-performance cosmetic active ingredients. With a strong commitment to scientific research and technological advancement, PuriPharm has established itself as a trusted partner for cosmetic formulators worldwide, delivering cutting-edge solutions that meet the evolving demands of the global beauty industry.
The company’s two flagship brand series, PuriActives® and NanoActive®, represent the pinnacle of cosmetic ingredient innovation. The PuriActives® series focuses on purified, high-potency active compounds derived from natural sources, while the NanoActive® series showcases PuriPharm’s expertise in advanced delivery systems, including liposomal, nanoemulsion, and encapsulation technologies. Together, these product lines offer formulators a comprehensive portfolio of solutions for creating next-generation skincare products.
PuriPharm maintains rigorous quality standards throughout its manufacturing processes, with state-of-the-art facilities equipped for advanced extraction, purification, and nano-formulation technologies. The company’s dedicated research and development team continuously explores new frontiers in cosmetic science, ensuring that PuriPharm remains at the forefront of ingredient innovation. By combining traditional botanical wisdom with modern scientific methodologies, PuriPharm creates ingredients that deliver measurable results while meeting the highest standards of safety and efficacy.
Contact Information
For product inquiries, technical support, or partnership opportunities:
PuriPharm Co. Ltd.
Website: www.puripharm.com
Product Series: PuriActives® | NanoActive®
NanoActive® RAL (Liposomal Retinal) Advanced Vitamin A Technology for High-Performance Skin Care
Company & Brand Background
PuriPharm Co. Ltd. is a science-driven company specializing in the research, development, and commercialization of high-performance functional bioactive ingredients. With a strong foundation in pharmaceutical science, biotechnology, and advanced formulation technologies, PuriPharm is dedicated to delivering safe, effective, and innovative active ingredient solutions for the global cosmetics, personal care, and biomedical industries.
PuriPharm operates two core product platforms:
• PuriActives® – a portfolio of high-quality functional bioactives derived from natural, bio-based, and scientifically validated sources.
• NanoActive® – an advanced nano-delivery ingredient platform designed to enhance the stability, bioavailability, and efficacy of sensitive active compounds through cutting-edge encapsulation technologies.
NanoActive® RAL (Liposomal Retinal) is a flagship product of the NanoActive® series, representing PuriPharm’s expertise in vitamin A chemistry, lipid delivery systems, and skin bioavailability optimization.
Retinal, also known as retinaldehyde (RAL), is a highly active form of vitamin A and a direct biochemical precursor of retinoic acid, the biologically active molecule responsible for many of vitamin A’s well-known skin benefits.
Unlike retinol, which requires a two-step enzymatic conversion process in the skin, retinal converts to retinoic acid in only one step. As a result, retinal delivers faster and more efficient biological activity at significantly lower concentrations.
Scientific and clinical studies have demonstrated that:
• Retinal converts to retinoic acid approximately 11 times faster than retinol
• Retinal offers efficacy comparable to retinoic acid but with significantly improved skin tolerance
• Retinal provides powerful anti-aging, skin-renewing, and collagen-stimulating effects with reduced irritation
For these reasons, retinal is widely recognized as one of the most advanced and effective vitamin A forms available for modern skin care formulations.
Why Choose Retinal Instead of Retinol?
Although retinol has long been used in cosmetic formulations, it presents several inherent limitations, including instability, oxidation, discoloration, and slow biological conversion.
Retinal offers distinct advantages:
• Faster efficacy – 11-fold faster conversion to retinoic acid compared with retinol
• Higher biological efficiency – closer to retinoic acid in the vitamin A metabolic pathway
• Improved skin tolerance – lower irritation potential compared with retinoic acid
• Broader functionality – supports anti-aging, acne control, skin tone improvement, and barrier repair
However, retinal itself is a chemically sensitive molecule that is prone to oxidation, light degradation, and discoloration. These challenges have historically limited its widespread use in cosmetic formulations.
NanoActive® RAL: Liposomal Retinal Technology
NanoActive® RAL overcomes the traditional limitations of retinal through an advanced liposomal nano-delivery system, enabling formulators to fully unlock the benefits of retinal in a stable, effective, and user-friendly form.
NanoActive® RAL is a lipid-encapsulated retinal, engineered using phospholipid bilayer technology that mimics the structure of biological cell membranes. This delivery system provides comprehensive protection and controlled release of retinal in the skin.
Key Features of NanoActive® RAL
• High stability – protected from oxidation, light exposure, and thermal degradation
• No discoloration – maintains formulation clarity and color stability over time
• Enhanced skin absorption – liposomal structure improves penetration and bioavailability
• Controlled release – gradual delivery minimizes irritation while maximizing efficacy
• Superior compatibility – easy to formulate into a wide range of cosmetic systems
Through nano-encapsulation, NanoActive® RAL ensures that retinal remains active, effective, and safe throughout the product’s shelf life and during skin application.
11 Times Faster Conversion to Retinoic Acid
One of the most important advantages of NanoActive® RAL is the intrinsic metabolic efficiency of retinal.
In the skin:
• Retinol → Retinal → Retinoic Acid (two-step conversion)
• Retinal → Retinoic Acid (one-step conversion)
This simplified pathway allows retinal to deliver results approximately 11 times faster than retinol, leading to quicker improvements in skin texture, tone, and visible signs of aging.
Because NanoActive® RAL enhances retinal delivery and stability, this rapid conversion can occur more efficiently and consistently within the skin.
Skin Benefits of NanoActive® RAL
NanoActive® RAL delivers a comprehensive range of clinically supported skin benefits:
Anti-Aging & Wrinkle Reduction
• Stimulates collagen and elastin synthesis
• Improves skin firmness, elasticity, and density
• Reduces the appearance of fine lines and wrinkles
Skin Renewal & Texture Improvement
• Accelerates epidermal cell turnover
• Smooths rough skin texture
• Promotes a more even and refined complexion
Brightening & Tone Correction
• Inhibits tyrosinase activity and melanin formation
• Enhances skin radiance and uniformity
• Helps fade hyperpigmentation and discoloration
Acne & Blemish Control
• Exhibits direct antibacterial activity against acne-causing bacteria
• Regulates sebum production
• Supports pore refinement and blemish recovery
Barrier Support & Repair
• Improves skin barrier integrity
• Enhances resilience against environmental stressors
• Supports long-term skin health and comfort
Superior Stability and Color Performance
Traditional retinal and retinol formulations often suffer from:
• Rapid degradation
• Yellowing or browning over time
• Loss of activity during storage
NanoActive® RAL is specifically designed to address these issues. The liposomal encapsulation effectively isolates retinal from environmental stress factors, resulting in:
• Excellent formulation stability
• Minimal color change over time
• Consistent performance throughout shelf life
This makes NanoActive® RAL ideal for premium skin care products where visual appearance, product consistency, and long-term efficacy are critical.
Easy Absorption & Skin Compatibility
The phospholipid-based nano-carriers used in NanoActive® RAL closely resemble the lipid structure of human skin. This biomimetic design allows for:
• Improved skin affinity
• Efficient penetration through the stratum corneum
• Targeted delivery to deeper skin layers
As a result, NanoActive® RAL is easily absorbed, non-greasy, and well tolerated, even in long-term use formulations.
NanoActive® RAL is suitable for a wide range of cosmetic and personal care applications, including:
• Anti-aging serums and creams
• Brightening and skin renewal products
• Acne treatment formulations
• Eye care products
• Barrier repair and post-treatment care
Its excellent compatibility allows formulators to incorporate NanoActive® RAL into emulsions, gels, lotions, and advanced delivery systems with ease.
A New Generation of Vitamin A Actives
By combining the proven biological power of retinal with state-of-the-art nano-delivery technology, NanoActive® RAL represents a new generation of vitamin A active ingredients.
It offers:
• Faster results than retinol
• Better tolerance than retinoic acid
• Greater stability than conventional retinal
• Enhanced user experience and formulation reliability
Conclusion
NanoActive® RAL (Liposomal Retinal) embodies PuriPharm Co. Ltd.’s commitment to scientific excellence, innovation, and performance. As a key product within the NanoActive® platform and a natural extension of the PuriActives® philosophy, NanoActive® RAL provides formulators and brands with a powerful, stable, and advanced vitamin A solution for next-generation skin care.
By delivering stable, non-discoloring, easily absorbed liposomal retinal with an 11-fold faster conversion to retinoic acid compared with retinol, NanoActive® RAL sets a new benchmark for efficacy, safety, and formulation sophistication in modern cosmetic science.
PuriActives®PuriVitin™
The Global Hydration Challenge
What Consumers Really Expect
The Problem with Conventional Humectants
A New Hydration Strategy
From temporary surface moisturization…
To skin-identical, biomimetic hydration.
Introducing PuriVitin™
What Is PuriVitin™?
Origin & Sustainability
Science Insight: Saccharide Isomers
Mechanism of Action
Hydration That Stays
Short & Long-Term Benefits
Visible Skin Improvements
FACIAL COLOR MAPPING TECHNOLOGY
Makes PURIVITIN benefits visible
3-HOUR after single applicationof 1% PURIVITIN dry cheek area is already betterhydrated.
Used for 28-DAYS, 1% PENTAVITIN®brings tired, dry skin back to life.
3% PURIVITIN compared to placebo
Three hours after single application of3%PURIVITIN significant hydration boost of forehead, eye region and cheek area.
After twice daily application for 28 days of 3% PURIVITIN®, there is highly significant hydration power to all facial areas.
PURIVITIN Reverse the 5 symptoms of dehydrated skin: roughness,dullness, flakiness, tightness, redness
PURIVITIN Reverse the 5 symptoms of dehydrated skin: roughness,dullness, flakiness, tightness, redness
PREBIOTIC SCALP MODULATION
PURIVITIN Rebalances scalp microbiomeinteraction in vitro
PURIVITIN For a well balanced scalp microbiome interaction
Consumer-Relevant Benefits
Conceptual Comparison
Versatile Application Areas
Formulation Advantages
Dosage & Use Level
Clean Beauty & Market Fit
Why Partner with PuriActives®?
PuriActives® PuriVitin™
1. PRODUCT IDENTITY
Trade Name: PuriActives® PuriVitin™
INCI Name (EU/US): Saccharide Isomerate, Aqua, Citric Acid, Sodium Citrate
CAS No.: 100843-69-4, 7732-18-5, 77-92-9, 68-04-2
Origin: 100% Plant-derived
General Description
PuriVitin™ is a highly effective, 100% plant-derived carbohydrate complex designed to provide deep, long-lasting hydration. Its unique composition is chemically similar to the carbohydrate fraction of the Natural Moisturizing Factor (NMF) found in human skin.
Unlike conventional humectants that can be easily washed off, PuriVitin™ binds physically to the skin’s keratin, creating a moisture reservoir that lasts for up to 72 hours. It is an essential active for formulations targeting instant hydration, barrier repair, and scalp comfort.
2. KEY BENEFITS & CLAIMS
“Magnet-Like” Skin Affinity
●Unique Binding Mechanism: PuriVitin™ binds to the epsilon-amino group of lysine in keratin. This unique binding mechanism ensures the active is not washed off by water, making it ideal for both leave-on and rinse-off products (e.g., shower gels, face cleansers).
●Long-Lasting Hydration: Provides sustained hydration for up to 72 hours, breaking the dry-skin cycle.
Skin Barrier Support
●Strengthens Barrier Function: Improves the skin’s defense against external aggressors (pollution, cold weather, dry air).
●Soothing Effect: Visible reduction in dryness, flakiness, and tightness associated with dehydrated skin.
●Scalp Care: effectively hydrates the scalp, reducing itchiness and improving the overall health of the scalp microbiome environment.
Sensory Profile
●Leaves skin feeling soft, plump, and smooth without stickiness.
3. COMPOSITION DATA
4. TECHNICAL SPECIFICATIONS
Physical & Chemical Properties
Microbiological Standards
5. MECHANISM OF ACTION
PuriVitin™ functions differently from traditional polyols (like glycerin) or macromolecules (like hyaluronic acid).
1.Isomerization: The glucose and fructose from plant kernels are isomerized to create a unique carbohydrate complex.
2.Bio-Mimicry: This complex mimics the composition of carbohydrates found naturally in the Stratum Corneum.
3.Keratin Binding: Upon application, PuriVitin™ forms a permanent bond with the keratinocytes. This bond is so strong that the moisture-locking effect persists until the dead skin cells naturally exfoliate (desquamation), ensuring hydration that outlasts washing.
6. APPLICATIONS & DOSAGE
Recommended Use Level: 1.0 – 5.0%
PuriVitin™ is suitable for a wide range of cosmetic applications:
Skin Care
●Daily Moisturizers: Day and night creams for instant and long-term hydration.
●Serums & Essences: Intensive hydration boosters.
●Anti-Aging: Plumps skin to reduce the appearance of fine lines caused by dehydration.
Rinse-Off Products
●Cleansers & Body Wash: Provides hydration that stays on the skin even after rinsing.
●Hand Soaps: Protects hands from dryness caused by frequent washing.
Hair & Scalp Care
●Shampoos & Conditioners: Hydrates the scalp to prevent flakes and itchiness.
●Hair Masks: Improves moisture retention in the hair shaft.
Body Care
●Body Lotions: For long-lasting comfort on dry areas (elbows, knees, heels).
7.FORMULATION GUIDELINES
●Solubility: Freely soluble in water. Insoluble in oils.
●Incorporation: Can be added to the water phase or at the end of the formulation process (cooling phase).
●Processing Temperature: Stable at temperatures up to 80°C. Can be processed hot or cold.
●pH Stability: Stable across a wide pH range (3.0 – 7.0 recommended for final formulation efficacy).
●Compatibility: Compatible with most cosmetic ingredients, including high concentrations of ethanol and electrolytes.
8. REGULATORY & STORAGE
Storage Conditions
●Store in the original, unopened container.
●Protect from direct sunlight and heat.
●Store at room temperature (15°C – 25°C).
Shelf Life
●36 months from the date of manufacture when stored under recommended conditions.
Packaging
●Standard industrial plastic containers (Drum/Jerry can).
Safety & Regulatory Status
●Vegan: Suitable for vegan formulations.
●Non-GMO: Produced from non-GMO plant sources.
●Preservative Status: Preservative-free (Self-preserving due to high solid content and osmotic pressure).
Disclaimer:
The information provided in this data sheet is based on our current knowledge and experience. It does not relieve the processor from carrying out their own tests and trials. A legally binding assurance of certain properties or suitability for a specific purpose cannot be derived from this data.
Manufacturer:
PuriPharm Co., Ltd.
PuriActives® is a registered trademark of PuriPharm Co., Ltd.
Nanao Active MN Overview
If you are Chinese, or if reading in Chinese is more convenient for you, you can access the Chinese product introduction PPT through this link.纳米包裹肉豆蔻醇烟酸酯
Nanao Active MN Overview
——Advanced Bioactive Ingredient for Skin and Haire Care
NanoActive RETINAMIDE
NanoActive RETINAMIDE is an innovative ingredient that combines the anti-aging benefits of retinamide with the advantages of nano-technology, designed to enhance skin penetration, stability, and bioavailability.Continue reading