PURIPHARM CO., LTD.
NanoActive™ BatyCer™
Batyl Alcohol Liposome
Advanced Biomimetic Skin Barrier Lipid Platform
Next-Generation Biomimetic Lipid Barrier Repair Technology
INCI NAME: BATYL ALCOHOL
SCIENTIFIC MARKETING DECK · INNOVATION FOR HEALTH & BEAUTY
02 · PARADIGM SHIFT
From Active Ingredients to Lipid Platform Innovation
Modern skincare is evolving from “hydration and moisturization” to skin-barrier lipid reconstruction.
From Hydration to Skin Barrier Lipid Reconstruction.
Core Trend
| Replenish lipid structural units | → | Restore the skin lipid ecosystem |
| Keyword | Meaning |
|---|---|
| Skin Barrier Science | Understanding skincare through barrier structure and function |
| Biomimetic Lipid | Mimicking the composition and environment of natural skin lipids |
| Lipid Architecture | Focusing on lipid composition, arrangement, and organization |
03 · SKIN BARRIER BIOLOGY
Stratum Corneum: The Body’s Natural Lipid Barrier System
The stratum corneum is composed of corneocytes and an intercellular lipid matrix, forming the classic brick-and-mortar structure. Corneocytes are the “bricks,” and intercellular lipids are the “mortar.” Lipid composition and organization directly determine barrier integrity and stability.
| Key Lipids | Barrier Functions |
|---|---|
| Ceramide | Moisture retention |
| Cholesterol | Protection against external stressors |
| Free fatty acid | Maintenance of softness |
Reference: van Smeden J, et al. Stratum Corneum Lipids: Their Role for the Skin Barrier. Biochim Biophys Acta.
04 · LIPID MATRIX SCIENCE
The Stratum Corneum Lipid Matrix: Synergy among Three Lipids
| Lipid | Structural Role |
|---|---|
| Ceramide NP | Forms highly ordered lipid layers and the structural backbone of the barrier |
| Cholesterol | Regulates lipid organization and fluidity to maintain dynamic matrix balance |
| Stearic Acid | Enhances lamellar stability and reinforces lipid-matrix morphology |
05 · HERO LIPID
Batyl Alcohol: Innovation through a Distinctive Ether-Lipid Structure
INCI Name: Batyl Alcohol
| 01 | Glycerol ether-lipid backbone: a glycerol lipid structure connected by an ether bond |
| 02 | Long-chain hydrophobic structure: high affinity with skin lipids |
| 03 | High lipid compatibility: readily integrates into a biomimetic lipid matrix |
| 04 | Biomembrane-related structure: derived from natural membrane-lipid chemistry |
Batyl Alcohol is not a conventional emollient lipid; it is a distinctive lipid with the potential to modulate membrane architecture.
Keywords: Ether Lipid · Membrane Architecture · Lipid Organization
06 · WHY BATYL ALCOHOL
Why Choose Batyl Alcohol?
| Conventional Lipid | Batyl Alcohol: Distinctive Ether Lipid |
|---|---|
| Provides an emollient skin feel; its effect remains at the sensory-modification level and does not participate in building the barrier-lipid structure. | 1. Lipid organization2. Membrane stabilization3. Biomimetic lipid-environment construction |
Core value: connecting natural membrane-lipid science with modern delivery technology.
07 · TECHNOLOGY ARCHITECTURE
How the NanoActive™ BatyCer™ Technology Is Built
Step 1: Lipid Composition
| Batyl Alcoholether-lipid anchor | → | Ceramide NP | → | Cholesterol | → | Phospholipid | → | Stearic Acid |
Step 2: Matrix Construction and Nano Delivery
| Biomimetic Stratum-CorneumLipid Matrix | → | PURISOME® LiposomeDelivery System | → | Skin BarrierLipid Platform |
Using Batyl Alcohol as the distinctive ether-lipid anchor, four classic barrier lipids are combined to build a biomimetic lipid matrix. The matrix is then delivered through the PURISOME® liposome system, forming a complete skin-barrier lipid platform.
08 · PURISOME® DELIVERY
PURISOME® Liposome Delivery Technology
| 01 | Nanoscale lipid carrier: nanoscale particle size suited to the skin-lipid environment |
| 02 | Mimics natural membrane architecture: a phospholipid-bilayer structure homologous to biological membranes |
| 03 | Improves lipid dispersion stability: addresses formulation challenges associated with high-melting-point lipids |
| 04 | Optimizes the application value of actives: enables lipid actives to be incorporated into formulations in a more favorable state |
Scientific Logic
| Lipid Active | → | Nano Encapsulation | → | Enhanced Delivery |
09 · BIOMIMETIC MECHANISM
Formation of the Biomimetic Lipid Matrix
| Natural Stratum Corneum | NanoActive™ BatyCer™ |
|---|---|
| CeramideCholesterolFatty acid | Batyl Alcohol (ether lipid)Ceramide NPCholesterolPhospholipidStearic Acid |
| The natural barrier-lipid combination provides the structural blueprint for biomimetic design. | A five-component biomimetic lipid combination strengthens the natural lipid paradigm with a distinctive ether lipid. |
NanoActive™ BatyCer™ mimics the natural lipid environment, using the lipid composition of the natural stratum corneum as a blueprint to reconstruct the structural order of a biomimetic lipid matrix.
10 · REPAIR MECHANISM
Four Mechanisms of Skin-Barrier Repair
| 01 | Lipid Replenishment: supplies key lipid structural units required by the stratum corneum |
| 02 | Lipid Organization: supports ordered lamellar organization of intercellular lipids |
| 03 | Moisture Retention: a complete lipid matrix helps reduce transepidermal water loss |
| 04 | Skin Comfort: improves tightness and discomfort associated with dryness and roughness |
The four mechanisms work together across the complete “replenish—organize—retain—comfort” pathway, intervening at the lipid-structure level rather than merely modifying surface feel.
11 · BEYOND HYDRATION
Beyond Hydration: From Hydration to Barrier Restoration
| Conventional Hydration | Barrier Lipid Care |
|---|---|
| Raises surface water content; the effect is concentrated in the upper stratum corneum and diminishes as water evaporates. | Improves lipid architecture by rebuilding order in the intercellular lipid matrix. |
| Hydration is the starting point of barrier care, but it cannot replace improvement of the lipid structure. | Reduces water loss because an intact lipid layer limits water escape. |
| — | Improves long-term comfort as barrier homeostasis supports lasting comfort. |
Moving from a temporary increase in water content to structural improvement of the barrier.
12 · CERAMIDE SCIENCE
The Scientific Value of Ceramide NP
| 01 | A core stratum-corneum lipid: ceramides are the most abundant lipid class in the intercellular lipid matrix |
| 02 | Maintains barrier integrity: supports the lamellar organization of intercellular lipids and continuity of the barrier structure |
| 03 | Supports skin softness: adequate ceramide levels are directly associated with a soft and supple skin feel |
Research indicates that a properly designed ceramide-delivery system can promote restoration of the skin-lipid structure.
Ceramide NP Structure
Ceramide NP consists of a sphingoid base linked to a fatty-acid chain through an amide bond. Its two long chains naturally suit the lamellar organization of intercellular lipids. In the BatyCer™ system, Ceramide NP works with Batyl Alcohol, cholesterol, phospholipid, and stearic acid to build a biomimetic lipid matrix.
| Fatty Acid Chain | → | Amide Bond | → | Sphingoid Base |
Reference: Coderch L, et al. Ceramides and Skin Function. American Journal of Clinical Dermatology.
13 · NANO DELIVERY VALUE
Nano Delivery Enhances the Application Value of Lipids
Traditional Route
| Ceramide Raw Material | → | Dispersion Challenge |
Ceramides have a high melting point and poor water solubility. Direct addition to a formula can cause crystallization and uneven dispersion, limiting the formulation window.
NanoActive™ Liposome Route
| Ceramide NP | → | Liposome Encapsulation | → | Uniform Lipid Environment |
PURISOME® liposomes encapsulate ceramides and other barrier lipids within a biomimetic phospholipid bilayer, creating a uniform and stable lipid-dispersion system in the formula and allowing barrier lipids to enter the development process in a more formulation-friendly form.
14 · EFFICACY MATRIX
Skincare Efficacy Matrix
| Core Efficacy | Applications |
|---|---|
| Barrier Strengthening | Barrier Repair Cream |
| Deep Moisturization | Barrier Serum |
| Skin Conditioning | Sensitive Skin Care |
| Dryness Improvement | Mature Skin Care |
| Skin Comfort | Product-development scenarios addressing barrier damage, dryness, and roughness |
15 · MATURE SKIN CARE
A Lipid-Care Direction for Mature Skin
Scientific Logic
| Aging | → | Lipid Profile Shift | → | Barrier Decline | → | Dryness & Roughness |
Barrier changes in mature skin are fundamentally changes in lipid composition and architecture—precisely where lipid care can intervene.
NanoActive™ BatyCer™ supports lipid care for mature skin by replenishing age-related lipid structural units through a biomimetic lipid matrix and pairing them with nano delivery to improve the application experience.
Keywords: Mature Skin · Lipid Replenishment · Barrier Care · Comfort
16 · SCALP SCIENCE
Scalp Barrier Science
The scalp is an extension of facial skin and likewise depends on an intact barrier system to maintain a healthy condition and comfortable feel.
| 01 | Stratum-corneum structure: the scalp surface also contains corneocytes and intercellular lipids |
| 02 | Lipid barrier: the lipid matrix maintains the integrity and stability of the scalp barrier |
| 03 | Moisture-regulation system: scalp moisture balance is closely linked to the state of barrier lipids |
Application Direction: Scalp Barrier Care—the extension of barrier-lipid science into scalp applications.
The scalp barrier shares its lipid environment with facial skin, so the biomimetic lipid-care logic can be transferred directly to scalp-care products.
17 · HAIR CARE VALUE
Value in Hair-Care Applications
Action Path
Hair Surface Lipid Conditioning
The lipid layer on the hair surface affects friction and fiber alignment. Conditioning this surface environment with biomimetic lipids can provide a smoother, glossier tactile and visual experience during hair care.
| Outcome | Application |
|---|---|
| Smoothness | Premium Shampoo & Conditioner |
| Shine | Hair Mask |
| Care Experience | Scalp Essence |
Extending barrier-lipid science from facial care to scalp and hair-fiber care.
18 · FORMULATION
Formulation Directions
| Recommended Formats | Synergistic Pairings |
|---|---|
| Barrier Cream | Ceramide: reinforces the barrier-lipid combination |
| Serum | Peptide: combines anti-aging and barrier care |
| Lotion | Retinoid: pairs with barrier care to improve formulation tolerability |
| Mask | Botanical Active: combines soothing action with barrier care |
| Scalp Essence | — |
The liposomal format is compatible with various aqueous and emulsified systems, giving formulation engineers flexibility in product development.
19 · TECHNICAL EDGE
Summary of Technical Advantages
| 01 | Batyl Alcohol ether-lipid platform: anchors membrane-lipid science in an ether-lipid structure to create a differentiated lipid core |
| 02 | Biomimetic stratum-corneum lipid matrix: combines Ceramide NP, cholesterol, phospholipid, and stearic acid to mimic the natural lipid environment |
| 03 | Ceramide NP synergy: replenishes a core barrier lipid and supports structural integrity of the stratum corneum |
| 04 | PURISOME® nano delivery: liposome-carrier technology improves lipid-dispersion stability and application value |
| 05 | Skin Barrier Lipid Platform: a platform-based barrier-care solution spanning skincare, scalp care, and hair care |
20 · INNOVATION VALUE
Scientific Innovation Value
| Traditional Approach | Upgraded Approach |
|---|---|
| Ingredient-Based Solution | Platform-Based Solution |
| Single-ingredient thinking · single-point efficacy narrative | Lipid-platform thinking · structured barrier solution |
NanoActive™ BatyCer™ redefines barrier-care ingredients: moving from providing one ingredient to providing a reusable skin-barrier lipid platform.
21 · SCIENTIFIC FOUNDATION
Scientific Research Foundation
| Research Pillars | References |
|---|---|
| Stratum Corneum Lipid Organization | [1] van Smeden J, et al. Stratum Corneum Lipids: Their Role for the Skin Barrier. Biochim Biophys Acta. |
| Ceramides & Skin Barrier Function | [2] Coderch L, et al. Ceramides and Skin Function. American Journal of Clinical Dermatology. |
| Liposome Delivery Systems | [3] Berkers T, et al. Lipid organization model studies. Langmuir. |
| Biomimetic Lipid Systems | [4] Ceramide liposome delivery studies. Pharmaceutics. |
The product-design logic is derived from the public skin-science literature. Complete bibliographic information can be provided separately.
22 · VALUE EQUATION
NanoActive™ BatyCer™ Technology Value Summary
| Batyl AlcoholEther Lipid Innovation | → | Ceramide NPBarrier Lipid Reconstruction | → | PURISOME®Advanced Delivery |
＝ Next-Generation Skin Barrier Lipid Platform
23 · MARKET LANDSCAPE
Application Markets
| 01 | Luxury Skincare |
| 02 | Dermocosmetics |
| 03 | Sensitive Skin Care |
| 04 | Premium Hair Care |
| 05 | Scalp Care |
One lipid platform spanning premium-care markets from face to scalp.
24 · COMPANY
PuriPharm Co., Ltd.
Innovation for Health & Beauty
Biotech · Dermocosmetics · Lipid Science · Nanotechnology
Website: www.puriactives.com
25 · CLOSING
NanoActive™ BatyCer™
The Future of Biomimetic Lipid Barrier Technology
PURIPHARM CO., LTD. · Innovation for Health & Beauty