PURIPHARM CO. LTD.
PuriActives® ZnHC
Zinc Hydrolyzed Collagen
The Science and Technology of Skin & Hair-Fiber Conditioning
“Condition the surface, reshape the environment.”
INCI NAME ZINC HYDROLYZED COLLAGEN
01 · PLATFORM POSITIONING
A New Perspective on Protein Conditioning
More than hydrolyzed collagen
The value of conventional hydrolyzed collagen centers on conditioning, hydration, and surface interaction. PuriActives® ZnHC adds zinc functionality on top of this peptide platform — building a differentiated ingredient story that extends from skin conditioning to sebum balance and scalp care.
Six directions: skin conditioning · water management · sebum balance · pore appearance · hair-fiber conditioning · scalp care
Figure 01 — Conceptual fusion of two functional platforms. Chemical concept illustration only; not a specific molecular structure.
01 · PLATFORM POSITIONING
What Is Zinc Hydrolyzed Collagen?
Zinc hydrolyzed collagen is the zinc-bound derivative of hydrolyzed collagen peptides — uniting a peptide-rich conditioning base with the functionality of Zn2+.
Controlled hydrolysis
Native collagen is degraded under controlled conditions into lower-molecular-weight peptide fractions — improving processability in aqueous systems and surface-interaction capability.
Zinc binding
Side-chain functional groups on the peptide backbone — carboxyl, amino, and hydroxyl — offer potential coordination environments for Zn2+ ions. No single defined molecular formula is implied.
Figure 02 — From collagen fiber to zinc-bound peptide network. Dashed lines indicate coordination — conceptual illustration, not a structural formula.
01 · PLATFORM POSITIONING
The Functional Architecture of PuriActives® ZnHC
Four functions, one peptide–mineral architecture — across skin, scalp, and hair fiber
Figure 03 — The four-function mechanistic architecture of the PuriActives® ZnHC platform.
02 · COLLAGEN PEPTIDE PLATFORM
Hydrolyzed Collagen — the Functional Peptide Base
Hydrolyzed collagen is not intact dermal collagen, but a mixture of collagen-derived peptide fractions whose performance is expressed at the skin-surface level — hydration, film formation, and conditioning.
Functional Highlights
› Hygroscopic amino-acid and peptide functional groups › Interaction with skin-surface water › Film-forming potential and surface affinity › Softness and conditioned after-feel › Hair-fiber affinity and anti-static performance › Established cosmetic biomaterial compatibility
Figure 04 — Peptide fraction distribution of hydrolyzed collagen (schematic). Topically applied hydrolyzed collagen does not rebuild the dermal collagen network.
“Hydrolyzed collagen acts mainly at the cosmetic contact interface — supporting hydration, conditioning, and surface quality.”
Aguirre-Cruz G, et al. Antioxidants (Basel). 2020;9(2):181. PMID: 32098294.
02 · COLLAGEN PEPTIDE PLATFORM
Water Management in the Stratum Corneum
Figure 05 — The “brick-and-mortar” model of the stratum corneum with a peptide-rich hydrating surface film (schematic).
Benefit Statements
› Supports skin hydration › Enhances softness › Improves conditioned after-feel › Helps reduce the perception of dryness and roughness
1 Collagen-derived peptides → 2 Water association + surface affinity
3 Hydrated interface → 4 Softer / smoother skin feel
A hydrated interface is a surface phenomenon — peptides associate with water and the stratum corneum to improve the conditioned feel of skin.
Supporting evidence: topical collagen literature — see References (03).
03 · ZINC FUNCTIONAL PLATFORM
Zinc — a Trace Element of Biological Significance
Zinc is a multifunctional bio-ion. Its biology spans enzyme catalysis, protein structure, cellular homeostasis, and epidermal function — a breadth rarely found in a cosmetic mineral ingredient.
Figure 06 — The zinc biology network relevant to cosmetic science (overview schematic).
“In cosmetic science, zinc chemistry builds a compelling bridge between skin-surface management and cellular stress biology.”
This page is presented as biological background for cosmetic innovation — not as medical dermatology.
03 · ZINC FUNCTIONAL PLATFORM
Zinc and Dermal-Matrix Stress Biology
Mechanistic evidence from a related zinc salt — in vitro human dermal fibroblasts: mechanistic context for zinc, not ingredient-specific data
Figure 07 — UVA / AP-1 / MMP-1 pathway and zinc intervention nodes, redrawn from the cited literature.
“Appropriately delivered zinc can engage pathways related to collagen homeostasis and photo-stress biology.”
Takino Y, Okura F, Kitazawa M, Iwasaki K, Tagami H. Int J Cosmet Sci. 2012;34(1):23–28. doi:10.1111/j.1468-2494.2011.00676.x — the study used zinc pyrrolidone carboxylate (Zinc PCA), not zinc hydrolyzed collagen.
04 · DIRECT INGREDIENT EVIDENCE
Direct Evidence for Zinc Hydrolyzed Collagen
KR20250138932A
Cosmetic composition comprising hydrolyzed collagen and zinc
Published September 23, 2025 · cited by publication number only
The patent explicitly describes zinc hydrolyzed collagen and benchmarks it directly against hydrolyzed collagen in paired toner, serum, and cream formulations — reporting superior oil-control and pore-related performance at equal addition levels.
Experimental Design
Zinc hydrolyzed collagen vs hydrolyzed collagen — tested across formulation formats: toner · serum · cream
Addition levels evaluated (as % of the tested collagen composition): 0.1% · 1% · 3% · 10%
Compared with matched hydrolyzed-collagen formulas at equal levels, the zinc hydrolyzed collagen formulas performed better on oil-control and pore-related measures.
One of the strongest pieces of ingredient-level direct evidence in this dossier.
Applicant information deliberately omitted; this dossier cites the patent literature by publication number only.
04 · DIRECT INGREDIENT EVIDENCE
Sebum Balance — Direct Ingredient Evidence
Formula-comparison data reported in the patent
Method — as reported in the patent
1 Full-face imaging under standardized conditions 2 T-zone selected for sebum-related analysis
3 ZnHC formula versus matched hydrolyzed-collagen formula 4 Toner, serum, and cream formats evaluated in parallel
Figure 08 — Directional schematic drawn from the comparative sebum evaluation reported in Figure 1 of KR20250138932A. Effect direction per the patent report; axis values not reproduced.
“Across toner, serum, and cream architectures, zinc binding moves hydrolyzed collagen beyond a conditioning position toward a broader oil-balance platform.”
04 · DIRECT INGREDIENT EVIDENCE
Visible Pore Care — a Differentiated Skin Opportunity
Figure 09 — Directional schematic drawn from the pore evaluation reported in Figure 2 of KR20250138932A. Effect direction per the patent report; axis values not reproduced.
Method — as reported in the patent
1 Full-face imaging before / after product use 2 Cheek and nose regions analyzed
3 Pore-related image metrics evaluated 4 ZnHC versus matched hydrolyzed-collagen formulas
From hydration → hydration + pore appearance + sebum balance
Cosmetic Benefit Statements
› Visible pore refinement › Finer-looking skin texture › Oil-balance support › A more refined skin appearance
Cosmetic appearance positioning only — no therapeutic claims such as acne treatment.
04 · DIRECT INGREDIENT EVIDENCE
How Zinc Rewrites the Hydrolyzed-Collagen Story
“From passive conditioning to multifunctional conditioning.”
| Functional Dimension | Hydrolyzed collagen | Zinc hydrolyzed collagen |
|---|---|---|
| Hydration & water support | ● | ● |
| Surface conditioning & film formation | ● | ● |
| Softness & smoothness | ● | ● |
| Hair-fiber affinity | ● | ● |
| Sebum-management opportunity | — | ● |
| Visible pore-care positioning | — | ● |
| Zinc-related biological significance | — | ● |
| Skin + scalp multifunctionality | — | ● |
The added dimensions are evidence-driven — anchored in the KR20250138932A comparison data and the zinc mechanism literature, not in claim language.
05 · PORE & TEXTURE CARE
Pore Care Is More Than “Astringency”
Five factors behind visible pores
01 Sebaceous gland activity — the flux of oil through the follicle
02 Surface topography — light reflection and micro-texture
03 Hydration status — stratum-corneum hydration and surface plumpness
04 Elasticity & structural support — firmness and recoil around the follicle
05 Follicle structure — the size, shape, and density of pore openings
Figure 10 — Follicle cross-section (schematic). Pore appearance is managed at the surface level; no permanent anatomical change is claimed.
Where ZnHC Fits
Sebum balance + surface conditioning + hydration + skin texture
✓ ”Helps refine the appearance of visible pores” ✕ ”Closes pores”
Positioning targets the cosmetic appearance of pores — not permanent pore reduction.
05 · PORE & TEXTURE CARE
A Texture Platform for Combination and Oily Skin
Translating scientific language into formulation and marketing language
Target Skin Profiles
Oily · combination · visible pores · rough texture · dehydrated-oily · urban-stressed skin
Balance Sebum-balance support in oily zones
Refine Refinement of visible pores and texture
Hydrate Peptide-based water management
Smooth A softer, smoother conditioned skin feel
Product Concepts for Formulators
› Pore-refining serum › Balancing serum › Lightweight gel-cream › Hydrating oil-control toner › Texture-conditioning treatment › Post-cleanse conditioning essence
Positioning language stays B2B and cosmetic in nature; final claims depend on the finished formulation.
06 · HAIR-FIBER CONDITIONING
From Skin to Hair — Why Protein Affinity Matters
“Hydrolyzed proteins are valued in hair care because low-molecular-weight peptide fractions can interact with damaged keratin surfaces.”
Damaged cuticle — bleaching, heat, and combing lift and erode the cuticle scales.
Peptide adsorption — peptide fractions preferentially adsorb at damaged surface sites.
Conditioned surface — a conditioned surface with improved feel and manageability.
Figure 11 — Peptide affinity at the damaged cuticle (schematic).
Classic substantivity evidence: Turowski A, et al. Substantivity to hair and skin of 125I-labelled collagen hydrolysates under application-simulating conditions. Int J Cosmet Sci. 1985;7:71–84. doi:10.1111/j.1467-2494.1985.tb00398.x
Surface adsorption is a cosmetic conditioning mechanism — not permanent structural repair.
06 · HAIR-FIBER CONDITIONING
Hair-Fiber Conditioning — Surface Science in Practice
Figure 12 — SEM-style cuticle schematic (redrawn illustration, not micrograph data). Peptide deposition preferentially occurs at damaged sites.
Protein-hydrolysate conditioning is a surface materials-science question — deposition, affinity, and film behavior at the fiber surface, unrelated to follicle biology.
Conditioning Outcomes
› Anti-static conditioning › Improved surface feel › Reduced roughness › Better combability › Softness and shine potential › Conditioning of damaged hair
Outcomes Are Modulated By
Molecular-weight distribution · peptide charge and degree of fiber damage · formulation environment · rinse-off versus leave-on contact
06 · HAIR-FIBER CONDITIONING
Damaged Hair Needs More Conditioning
Processing & Treatment Stressors
Bleaching · coloring · perming · heat · UV · mechanical combing
What Increases at the Fiber Surface
Cuticle irregularity · surface friction · porosity · protein loss · static charge · roughness
The Conditioning Response
Peptide-rich conditioning — preferential interaction with damaged surfaces
Improvement in cosmetic surface quality
Supported by the peer-reviewed hair-fiber conditioning literature (see References). Oral collagen-supplementation studies are not used as evidence for topical hair-fiber claims.
07 · SCALP & PORTFOLIO
Scalp Care — Where Skin Science Meets Hair Science
“The scalp is skin — with an active sebaceous environment.”
Figure 13 — Scalp mechanism map: four converging care pathways.
Positioning
› Oily-scalp care › Scalp hydration › Scalp conditioning › Sebum-balance concepts › Scalp comfort › Hair-root environment
Potential Applications
Scalp serums · shampoos · scalp treatments · conditioners · hair masks · leave-on care
No claims are made regarding the treatment of seborrheic dermatitis, hair loss, or dandruff.
07 · SCALP & PORTFOLIO · SIGNATURE
One Ingredient — Two Beauty Territories
“One peptide–mineral platform connecting skin science and hair science.”
08 · FORMULATION & EVIDENCE MAP
Formulation Opportunities
One ingredient, three formulation territories — from daily skincare to targeted scalp and hair systems
| Skin Care | Scalp Care | Hair Care |
|---|---|---|
| Toners | Scalp essence water | Shampoos |
| Essence waters | Scalp serums | Conditioners |
| Serums | Balancing lotions | Hair masks |
| Gel-creams | Pre-wash treatments | Leave-in conditioners |
| Creams | Repair serums / sprays | |
| Masks |
Published Formulation Precedent
KR20250138932A evaluated collagen compositions containing zinc hydrolyzed collagen in toner, serum, and cream prototypes at 0.1–10% addition. This range is cited as a published precedent only — it is not the official recommended dosage for PuriActives® ZnHC. Please refer to PuriPharm technical specifications.
08 · FORMULATION & EVIDENCE MAP
Formulator’s Scientific Snapshot
| Trade name | PuriActives® ZnHC |
| INCI | ZINC HYDROLYZED COLLAGEN |
| Product platform | Zinc-functionalized collagen-peptide conditioning system |
| Core benefits | Skin conditioning · water support · visible pore-care positioning · sebum-balance positioning · hair-fiber conditioning · scalp-care support |
| Target applications | Skin care · scalp care · hair care |
| Evidence platform | Direct patent evidence for zinc hydrolyzed collagen · hydrolyzed-collagen literature · zinc-mechanism literature · hair-substantivity literature |
Technical Specifications
pH, solids content, molecular-weight distribution, zinc content, preservation system, appearance, recommended dosage, and stability data are governed by PuriPharm technical documentation. They are deliberately not reproduced in this presentation.
08 · FORMULATION & EVIDENCE MAP
The Evidence Map — from Direct Data to Mechanistic Support
Level 1 — Direct ZnHC evidence KR20250138932A — oil-control and pore-related performance in toner, serum, and cream formulations.
Level 2 — Hydrolyzed-collagen evidence Topical hydration, surface conditioning, skin and hair substantivity (Aguirre-Cruz 2020; Turowski 1985).
Level 3 — Zinc-mechanism evidence Matrix-stress and sebaceous-biology context (Takino 2012 — Zinc PCA, in vitro).
Level 4 — Formulation science Peptide adsorption, hair-fiber interaction, and surface-conditioning science.
Indirect evidence supports mechanism and ingredient-class context — it is not clinical proof of finished-product performance.
08 · FORMULATION & EVIDENCE MAP · ONE-PAGE STORY
PuriActives® ZnHC — the Product Story on One Page
Condition — collagen-derived peptides support the surface quality of skin and hair.
Hydrate — a peptide-rich interface supports water retention and softness.
Balance — zinc functionality extends the platform to sebum and pore care.
Connect — one ingredient linking skin, scalp, and hair-care innovation.
“Peptide conditioning, empowered by zinc.”
09 · REFERENCES
Scientific References
Core literature supporting this dossier, ranked by evidentiary proximity to zinc hydrolyzed collagen
01 KR20250138932A. Cosmetic composition comprising hydrolyzed collagen and zinc. Korean patent publication, September 23, 2025 — cited by publication number only. Ingredient-level direct evidence: comparative oil-control and pore-related evaluation in toner, serum, and cream formulations.
02 Takino Y, Okura F, Kitazawa M, Iwasaki K, Tagami H. Zinc L-pyrrolidone carboxylate inhibits the UVA-induced production of matrix metalloproteinase-1 by in vitro cultured skin fibroblasts, whereas it enhances their collagen synthesis. International Journal of Cosmetic Science. 2012;34(1):23–28. doi:10.1111/j.1468-2494.2011.00676.x
03 Aguirre-Cruz G, León-López A, Cruz-Gómez V, Jiménez-Alvarado R, Aguirre-Álvarez G. Collagen Hydrolysates for Skin Protection: Oral Administration and Topical Formulation. Antioxidants (Basel). 2020;9(2):181. doi:10.3390/antiox9020181. PMID: 32098294
04 Turowski A, et al. Substantivity to hair and skin of 125I-labelled collagen hydrolysates under application-simulating conditions. International Journal of Cosmetic Science. 1985;7:71–84. doi:10.1111/j.1467-2494.1985.tb00398.x
05 Burnett CL, Bergfeld WF, Belsito DV, et al. Safety Assessment of Skin and Connective Tissue-Derived Proteins and Peptides as Used in Cosmetics. International Journal of Toxicology. 2022. doi:10.1177/10915818221104783
For further literature on topical collagen hydrolysates, zinc biology, and hair surface science, see the complete PuriPharm technical dossier.
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